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HES-SO Valais-Wallis
Page 1
Centre d’innovation des
technologies de la sante
HES-SO Valais Wallis
Un support pour les deci...
HES-SO Valais-Wallis
Page 2
Health Technology
Innovation Center (HTIC)
•  Systems Engineering Institute:
Prof. Martial Gei...
HES-SO Valais-Wallis
Page 3
Vision
To position HES-SO Valais Wallis
as a leader in Switzerland & internationally
in Sustai...
HES-SO Valais-Wallis
Page 4
Motivation
•  Situation:
•  aging society, increasing numbers of patients with chronic disease...
HES-SO Valais-Wallis
Page 5
Mission of HTIC
•  Create an interdisciplinary research Center on health
technology with a suf...
HES-SO Valais-Wallis
Page 6
Positioning
Fundamental
Research
(EPFL Valais)
aR&D
(HES-SO VS)
Valorisation
(The Ark)
Industr...
HES-SO Valais-Wallis
Page 7
Stategic Axes: full value chain
•  Early diagnostics tools
•  Sensor developments
& integrated...
HES-SO Valais-Wallis
Page 8
eHealth Unit Sierre
27 collaborators
3 professors, 7 engineers, 6 postdocs, 11 PhD students
Ma...
HES-SO Valais-Wallis
Page 9
Physio-
logical
values
Monitoring
Decision
support
Electronic Health Records:
(Patient history...
HES-SO Valais-Wallis
Page 10
HTIC
Example projects
HES-SO Valais-Wallis
Page 11
Gestational Diabetes Mellitus
GDM occurs during pregnancy (4%)
due to increased resistance to...
HES-SO Valais-Wallis
Page 12
Demo
HES-SO Valais-Wallis
Page 13
MIRTH
MIRTH
BodyTel
Body
Area Network
Interoperability
Middleware
Intelligent Agents (GOLEM)
...
HES-SO Valais-Wallis
Page 14
Commodity12 DEMO: Hypoglicemia
•  BodyTel Body Area Network, with glucose value sent the inte...
HES-SO Valais-Wallis
Page 15
DiagnosticAID (2012-2014)
Objective:
•  Interoperability with external health systems
•  Clin...
HES-SO Valais-Wallis
Page 16
Measure of the Knie Deviation
•  Goal: Diagnostic of arthritis
•  Means:
•  System to measure...
HES-SO Valais-Wallis
Page 17
NinaPro: Non Invasive Adaptive Hand Prosthetics
GOALS
1.  Augment Dexterity of Robotic Prosth...
HES-SO Valais-Wallis
Page 18
Step 1: Nina-Pro Electro Myography Database
Step 2: Posture Classification
Step 3: Natural Co...
HES-SO Valais-Wallis
Page 19
Project „ISyPeM II“
Ø  Evolution in TDM
0	
   1	
   2	
   3	
   4	
   5	
   6	
   7	
   8	
 ...
HES-SO Valais-Wallis
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Project „ISyPeM II“
Ø  Point-of-care (POC) solution
HES-SO Valais-Wallis
Page 21
INTERPRETATION AND DOSE
ADJUSTMENT

§  Is the result expected ?
§  Is the drug still suitab...
HES-SO Valais-Wallis
Page 22
Project Idea „Breathx“
Ø  Mobile breath analysis
Air composition incl. metabolites change:
•...
HES-SO Valais-Wallis
Page 23
Project Idea „Breathx“
Ø  Mobile breath analysis
Goal:
•  Understand relationship breathing ...
HES-SO Valais-Wallis
Page 24
Thank you
Picture:http://
biomedicalcomputationreview.org
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Centre d’innovation des technologies de la santé HES-SO Valais-Wallis

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A l'occasion de la 2ème journée valaisanne de recherche translationnelle en réadaptation, Prof. Dr. Schumacher a présenté le nouveau Centre d’innovation des technologies de la sante HES-SO Valais-Wallis.

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Centre d’innovation des technologies de la santé HES-SO Valais-Wallis

  1. 1. HES-SO Valais-Wallis Page 1 Centre d’innovation des technologies de la sante HES-SO Valais Wallis Un support pour les decisions liées à la santé Prof. Dr. Michael Schumacher & Prof. Dr. Marc Pfeifer 2ème journée valaisanne de recherche translationnelle en réadaptation, Sion, 3.3.2014
  2. 2. HES-SO Valais-Wallis Page 2 Health Technology Innovation Center (HTIC) •  Systems Engineering Institute: Prof. Martial Geiser & Prof. Pierre Roduit •  Institute of Life Technologies: Prof. Marc Pfeifer & Prof. Jean-Manuel Segura •  Institute of Information Systems: Prof. Michael Schumacher & Prof. Henning Müller •  Institut de recherche Santé-Social: Prof. Roger Hilfiker & Patricia Pham & Peter Voll •  IEM: Prof. Eric Michellod & Prof. Alexandra Hugo •  Institute of Tourisme: Prof. Marc Schnyder & Rafael Matos Bottom-up! initiative!
  3. 3. HES-SO Valais-Wallis Page 3 Vision To position HES-SO Valais Wallis as a leader in Switzerland & internationally in Sustainable Health Technology
  4. 4. HES-SO Valais-Wallis Page 4 Motivation •  Situation: •  aging society, increasing numbers of patients with chronic diseases, and late-stage and expensive treatments •  Paradigm shift is needed to enhance: •  Early detection and prevention of diseases •  Healthy behavior & nutrition •  Patient empowerment & health literacy •  Chronic disease management •  Socially integrated care and independent living Picture source: http://www.sustainablehealth.org/sustainable-health/our-approach/
  5. 5. HES-SO Valais-Wallis Page 5 Mission of HTIC •  Create an interdisciplinary research Center on health technology with a sufficient critical mass •  Acquire national and international research projects •  Translate fundamental research to aR&D •  Transfer innovation to industry (prototype developement) •  Transfer competencies to our students •  Position HES-SO Valais towards EPFL Valais & HES-SO
  6. 6. HES-SO Valais-Wallis Page 6 Positioning Fundamental Research (EPFL Valais) aR&D (HES-SO VS) Valorisation (The Ark) Industry Health Technology Innovation Center (HTIC) Translate fundamental research into industrial practice (Science to Market)
  7. 7. HES-SO Valais-Wallis Page 7 Stategic Axes: full value chain •  Early diagnostics tools •  Sensor developments & integrated devices •  eHealth applications •  Healthy food Institute of Life Technologies Systems Engineering Institute Institute of Information Systems Institute of Life Technologies ß  Focus on health innovation mainly outside hospital à ß  Ethically-driven technology development to fully respect & serve human life à InstitutSantéSocial InstituteofTourism InstituteofMangement
  8. 8. HES-SO Valais-Wallis Page 8 eHealth Unit Sierre 27 collaborators 3 professors, 7 engineers, 6 postdocs, 11 PhD students Many visiting researchers and exchanges with other research groups & companies 60 peer reviewed publications in 2012 1 startup company in 2013. Possible others startups in preparation Projects 2013: 8 EU FP7 projects 4 FNS + 2 Nano-Tera CTI, TheArk, Hasler, … Mandates
  9. 9. HES-SO Valais-Wallis Page 9 Physio- logical values Monitoring Decision support Electronic Health Records: (Patient history) Individualized multi-parametric data analysis Bio-markers & Sensors Models (Formal reasoning and machine learning) Medical guidelines Medical litterature Hospitals GPs & Nurses Labs Interoperability Coordination of care Acute & Chronic individual care management Medical data warehouse Signal processing Multiparametric Decision Support
  10. 10. HES-SO Valais-Wallis Page 10 HTIC Example projects
  11. 11. HES-SO Valais-Wallis Page 11 Gestational Diabetes Mellitus GDM occurs during pregnancy (4%) due to increased resistance to insulin Goal of the project: 1.  Constant monitoring and recording to ease treatment adjustment 2.  Automatic alerts to medical staff Technologies: Market sensors (glucometers) Smart phones & Web Apps Expert Systems
  12. 12. HES-SO Valais-Wallis Page 12 Demo
  13. 13. HES-SO Valais-Wallis Page 13 MIRTH MIRTH BodyTel Body Area Network Interoperability Middleware Intelligent Agents (GOLEM) Arrhythmia Detection Breathing Detection Noise Detection Temporal Reasoning Guidelines Reasoning Physio- logical Signals HL7 Portavita Care Management System Events/Findings/Alerts Alerts Similar patient search Visualisation HL7 HL7 Continuous Multi-parametric and Multi-layered analysis of Diabetes 1 & 2
  14. 14. HES-SO Valais-Wallis Page 14 Commodity12 DEMO: Hypoglicemia •  BodyTel Body Area Network, with glucose value sent the interoperability layer •  The expert systems applies a set of rules to deal with hypoglicemia: •  The alert is displayed in PortaVita Care Management System
  15. 15. HES-SO Valais-Wallis Page 15 DiagnosticAID (2012-2014) Objective: •  Interoperability with external health systems •  Clinical decision support system backed by computerized clinical guidelines for Mediway
  16. 16. HES-SO Valais-Wallis Page 16 Measure of the Knie Deviation •  Goal: Diagnostic of arthritis •  Means: •  System to measure knie deviation •  Data acquisition •  Software for physiotherapists with data acquisition, visualization and analysis •  HES-SO Partners: •  Systems Engineering Institute (Pierre Roduit) •  Institute of Health (Roger Hilfiker) •  Institute of Information Systems (Michael Schumacher) Used sensors: gyroscope, accelerometer, compass
  17. 17. HES-SO Valais-Wallis Page 17 NinaPro: Non Invasive Adaptive Hand Prosthetics GOALS 1.  Augment Dexterity of Robotic Prosthesis 2.  Reduce Training Time
  18. 18. HES-SO Valais-Wallis Page 18 Step 1: Nina-Pro Electro Myography Database Step 2: Posture Classification Step 3: Natural Control Step 4: Adaptive Learning NinaPro: Steps
  19. 19. HES-SO Valais-Wallis Page 19 Project „ISyPeM II“ Ø  Evolution in TDM 0   1   2   3   4   5   6   7   8   9   10   11   12   Treatment  dura5on  (days)   Drug  Concentra5on   (μg/mL)   0.0   0.4   0.8   1.2   1.6   2.0   2.4   Pa5ent   Target   800  mg  qd   Risk  of  adverse  effects     Risk  of  inefficacy   Ima5nib  400  mg  qd  
  20. 20. HES-SO Valais-Wallis Page 20 Project „ISyPeM II“ Ø  Point-of-care (POC) solution
  21. 21. HES-SO Valais-Wallis Page 21 INTERPRETATION AND DOSE ADJUSTMENT §  Is the result expected ? §  Is the drug still suitable ? §  Prediction and dose adjustment Project „ISyPeM II“ Ø  Point-of-care (POC) solution DATA EXCHANGE AND INTEROPERABILITY §  Upload patient’s data §  Extension of eHealth medical standards §  Data integrity
  22. 22. HES-SO Valais-Wallis Page 22 Project Idea „Breathx“ Ø  Mobile breath analysis Air composition incl. metabolites change: •  Infection (bacterial, fungi, viral) •  Injury and / or inflammation •  Disease (lung cancer, …) •  Pharmaceutical and food / beverage intake •  During exercise or rest (ventilated) •  Fitness
  23. 23. HES-SO Valais-Wallis Page 23 Project Idea „Breathx“ Ø  Mobile breath analysis Goal: •  Understand relationship breathing ↔ recovery •  Optimize recovery / rehabilitation Approach: •  Select metabolic markers •  Select or develop wearable sensor device •  Software and Data management •  Clinical result evaluation
  24. 24. HES-SO Valais-Wallis Page 24 Thank you Picture:http:// biomedicalcomputationreview.org

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