What is Xerostomia?
 
Xerostomia is the medical term for a dry mouth due to the
lack of saliva

Xerostomia can lead to a b...
Types of Xerostomia
Salivary glands

1

IRREVERSIBLE
Salivary glands produce NO
saliva (Sjögren’s Syndrome,
radiotherapy t...
How to relief Xerostomia?
Chewing

Xylitol

+

Chewing sugarfree
gum, increases
salivary flow in patients
with xerostomia ...
Which active ingredients can help with
Xerostomia?
1

ACIDS
Like malic acid or ascorbic
acid

2

ENZYMES
Like lactoperoxid...
Is chewing gum effective in stimulating
salivary flow?
Mastication is agreed to be the main reason for saliva stimulation
...
Studies: chewing gum and salivary flow rate
A study into the effects of chewing duration and frequency
on the flow rate of...
Studies: chewing gum and salivary flow rate
The flow rate was independent of chewing frequency within
a range of 35 to 130...
Conclusion
Chewing gum is a potent and fast stimulant of salivary flow
rate, being a very effective way to relief Xerostom...
Sources:
EFSA Journal
Cro.sagepub.com
Dentaid.com
Medicalnewstoday.com
Wrigley
Benefits of medicated chewing gum in patients with Xerostomia
Benefits of medicated chewing gum in patients with Xerostomia
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Benefits of medicated chewing gum in patients with Xerostomia

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Health in Gum is the best option to your new medicated chewing gum against Xerostomia

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Benefits of medicated chewing gum in patients with Xerostomia

  1. 1. What is Xerostomia?   Xerostomia is the medical term for a dry mouth due to the lack of saliva Xerostomia can lead to a bad breath, a dramatic rise in the number of cavities as the protective effect of saliva is no longer present, and can make the mouth more vulnerable to infection and ulceration
  2. 2. Types of Xerostomia Salivary glands 1 IRREVERSIBLE Salivary glands produce NO saliva (Sjögren’s Syndrome, radiotherapy treatment) 2 REVERSIBLE Reduction in salivary gland function
  3. 3. How to relief Xerostomia? Chewing Xylitol + Chewing sugarfree gum, increases salivary flow in patients with xerostomia by up to 7 times Xylitol is proven to prevent harmful bacteria from growing and harmful plaque from building up on teeth
  4. 4. Which active ingredients can help with Xerostomia? 1 ACIDS Like malic acid or ascorbic acid 2 ENZYMES Like lactoperoxidase, lysozyme or lactoferrin
  5. 5. Is chewing gum effective in stimulating salivary flow? Mastication is agreed to be the main reason for saliva stimulation during gum chewing Furthermore intensity of mastication is positively related to salivary flow
  6. 6. Studies: chewing gum and salivary flow rate A study into the effects of chewing duration and frequency on the flow rate of whole saliva, by the International and American Association for Dental Research, revealed that salivary flow rate peaked during the first minute of chewing
  7. 7. Studies: chewing gum and salivary flow rate The flow rate was independent of chewing frequency within a range of 35 to 130 chewing maneuvers per minute The influence of sample size (weight) of chewing gum on saliva flow was assessed by means of gums weighing from 1 to 9 g The 1-g piece led to a four-fold, the 9-g piece to a 13-fold increase in salivary flow The size of a piece of chewing gum can have a significant influence on salivary flow rate
  8. 8. Conclusion Chewing gum is a potent and fast stimulant of salivary flow rate, being a very effective way to relief Xerostomia The addition of specific active ingredients- acids or enzymes- in the gum can also improve such positive effects Cafosa presents Health in Gum®, the ideal excipient to formulate and produce medicated chewing gum by direct compression, using standard pharmaceutical equipment The best option to your new medicated chewing gum against Xerostomia
  9. 9. Sources: EFSA Journal Cro.sagepub.com Dentaid.com Medicalnewstoday.com Wrigley

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