Antibiotics

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synthetic antbiotics

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Antibiotics

  1. 1. Start with the name of Allah ,the most Beneficent and most Merciful
  2. 2. Presented By: Hina Mahmood Supervisor: Dr. Shaukat Ali Registration No. 2012-ag-1546 University of agriculture, Faisalabad
  3. 3.  Definition  Composition/structure  Mechanism of action  Application  Advantages  Disadvantages  conclusion
  4. 4. Antibiotics : Substance (such as penicillin) that destroys or inhibits the growth of other pathogenic microorganisms and is used in the treatment of external or internal infections.
  5. 5. Synthetic antibiotics: Penicillin Cephalosporin Chloramphenicol Vancomycin Polymycin Bacitracin  Aminoglycosides (gentamycin) Tetracycline Macrolides  Clindamycin  Streptogramins  Fluoroquinolones (ciprofloxacillin)  Metronidazole  Rifampin  Isoniazid  Sulfonamides  Trimethoprim
  6. 6. Synthetic antibiotics: general structure of penicillin
  7. 7. Members of penicillin class: Penicilin G ampicillin, penicilin v ticarcillin
  8. 8. Members of penicillin class:  Cloxacillin amoxicillin oxacillin, nafcillin
  9. 9. Member of Cephalosporin class  cefadroxil, cephalexin, cefazolin, cephapirin
  10. 10. Classification of antibiotics : Antibiotics are classified several ways.  On the basis of mechanism of action  On the basis of spectrum of activity  On the basis of mode of action
  11. 11. Chloramphenicol
  12. 12. Mechanism for the synthesis of Chloramphenicol
  13. 13. Chloramphenicol  First isolated from Streptomyces Venezuelae  Useful for eye infections  Cause bone marrow depression  Broad-spectrum antibiotic  Interfering with bacterial protein synthesis  bacteriostatic  aplastic anemia  Through oral route
  14. 14. Inhibition of protein synthesis
  15. 15.  Do not use Antibiotics in viral disease
  16. 16.  Viral diseases diarrhea FeverFlu or Cold Pneumonia
  17. 17. Advantages  treat many diseases  selectively toxic to microorganisms  for treatment of cancer  Also used to treat infectious diseases in animals  to control bacteria and fungi that damage fruit and grain  as food preservatives  help the body fight off infections or other bacterial issues  in some cases prevent, bacterial infections
  18. 18. Disadvantages  Can react with other medications  Cause resistance  Side effects
  19. 19. Antibiotics side effects: Diarrhoea Bloating and indigestion Abdominal pain Loss of appetite Feeling sick Itchy skin rash Coughing life-threatening allergic reaction
  20. 20. Unconsciousness of Patient • Intake of antibiotic without proper direction • Dosage intervals and completion of the dose. •Patient stop the drug when feel better.
  21. 21. What Is The Rules Of Pharmacist The pharmacist should review:  the previous diseases history.  Hypersensitivity reaction of Drug  Drug-drug interaction  Exact dose and frequency of the drug  Timing of the drug.  Ending of the drug
  22. 22. My Opinion The doctor should:  concern the disease.  concern the prescription of the drug The pharmacist should be conscious:  about the dose  drug interaction  resistant  hypersensitivity of the drug . The patient should:  strictly maintain the suggestion of the pharmacist.

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