Vehicles For Pharmaceutical
Substance which are of little or no therapeutic
value but which are added to the formulation in
order to :-
Help the production.
Maintain physiologically stability.
Improve patient acceptability.
To improve the functioning of the dosage form
as a DDS.
Pharmceuticals aids necessities adjuvants or
Do not impart any undesired taste , colour, and
Non toxic , Non irritant , Non sensitizing
Effective in low concentration
Free from microorganism
Not interfere with bioavailability of the drug
Accepted by regulatory authorities
Medium in which ingredients of a formulation are
dissolve suspended or dispersed.
Pharmaceuticals vehicles can be classified as under-
Vehicles can be of many types depending their use
and route of administration.
The vehicle can be of any type oily , aqueous , solid
and semi solid type
Water , Aromatic water , Alcohol , Glycerine ,
Vegetables oils , Minerals oils , Organic oils
bases Or Emulsified bases.
Vehicles in liquid dosage form
Cacao butter , Adeps neutralis
PEGs or Glycerinated , gelatine
Solid and Semi Solid
Sugar and gum
Semi solid dosage form
Creams and Gels
White petroleum , lanolin, cholesterol
Hydro alcoholic , Alcoholic and Non aqueous