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Global HealthResearch inSan FranciscoCasting the NetPaul Volberding
Perspectives on GlobalHealth Research and UCSFPast, Present, Future Pre-HIV epidemic: TB, reproductive rights, parasitic ...
Recent History Haile Debas steps down from GHS, Jaime  Sepulveda recruited Strategic planning begun immediately and to s...
Charge to CollectInformation GHS Research Team appointed:    Craig Cohen, Paul Volberding: Co-Chairs    Colin Boyle   ...
GHS Research Community Discussions Parameters, objectives:  Site: All at Mission Bay to reinforce as “home”  Three meet...
The Community Discussions Basic Science: August 28th. Genentech Hall. 25  attendees representing  UCSF, Gladstone, GB3, C...
Guide for CommunityDiscussions   Global Health Research at UCSF Community Discussion Guide   Vertical Priorities and Hor...
Strategic Planning:Verticals, Horizontals
Take-Homes for Today’sConsideration: Meeting 1   The perception of a separation between that community and the clinical a...
Take-Homes for Today’sConsideration: Meeting 2   Vigorously endorsed cross-disciplinary collaboration   The “verticals” ...
Take-Homes for Today’sConsideration: Meeting 3 Most institutions have given up the vertical /horizontal model in the 70’s...
Take-Homes for Today’sConsideration: Meeting 3   IRAC summarized as example of attempt to break down barriers and engage ...
Where Next? Community of global health research large, broad,  complex Strong desire to work together and decrease isola...
Improvement Opportunities Time-limited community discussions with regional  or discipline focus Ongoing discussion group...
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Volberding GHS Research 10 11 12

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Dr Paul Volberding addressing the GHS/CFAR retreat, identifying opportunities for GHS to support and abut the research undertaken by UCSF faculty in an international context.

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Volberding GHS Research 10 11 12

  1. 1. Global HealthResearch inSan FranciscoCasting the NetPaul Volberding
  2. 2. Perspectives on GlobalHealth Research and UCSFPast, Present, Future Pre-HIV epidemic: TB, reproductive rights, parasitic infections, others. (Department of Epidemiology and International Health) GHS: Focused program with aspirations. Investigative group. Educational effort. HIV not a central focus as Haile had established ARI in 1996. HIV: ARI established to counter perception of fracturing, competing effort. ARI as a loose, minimally resourced “umbrella” charged with creating/sustaining a community of science encompassing individual PIs and larger groups (CFAR, CAPS, HIV/AIDS Division, GIVI and, later, DEM).
  3. 3. Recent History Haile Debas steps down from GHS, Jaime Sepulveda recruited Strategic planning begun immediately and to some degree still in progress Research a key element of planning along with education and other elements. Structure TBD. Directions open for adding to GHS research portfolio:  Grow within existing GHS  Add programs to GHS (GHS as center of “federation”)  GHS as ARI-like umbrella  Combination of above
  4. 4. Charge to CollectInformation GHS Research Team appointed:  Craig Cohen, Paul Volberding: Co-Chairs  Colin Boyle  Phil Rosenthal  Jim McKerrow  Madhavi Dandu  Dominic Montagu  Sarah Royce  Caryn Bern  Georgina Lopez Met to develop approach Produced three focused community discussions
  5. 5. GHS Research Community Discussions Parameters, objectives:  Site: All at Mission Bay to reinforce as “home”  Three meetings, each with discipline theme  Basic sciences (drug and assay discovery, etc.)  Clinical/translational sciences  Population, prevention, policy and implementation sciences  Participants: Wide. Slant to established investigators. All sites, schools, affiliates.  Objectives: Open but guided dialog, ideas sought, no input excluded.  Summaries prepared for further consideration.
  6. 6. The Community Discussions Basic Science: August 28th. Genentech Hall. 25 attendees representing UCSF, Gladstone, GB3, Cancer Center, others. Clinical Science: August 29th. Genentech Hall. 62 attendees representing SOM, SOP, GHS, CTSI, Cancer Center, others. Population Science: September 25th. CVRI. 45 attendees representing IHPS, orthopedics, OB/GYN, FCM, DGIM, others.
  7. 7. Guide for CommunityDiscussions Global Health Research at UCSF Community Discussion Guide Vertical Priorities and Horizontal Linkages (Cross-Cutting Programs) 1. What field(s) of research does UCSF have particular strength which is/has potential for expansion as a priority area in global health. Discuss why this particular field has promise for expansion. 2. What field(s) of research does UCSF not currently have considerable strength, but has potential for expansion in global health.  Include your perspective on why this particular field has promise for expansion. 3. What “horizontal linkages” (e.g. implementation research, drug discovery) does UCSF have strengths which have potential for further expansion in to global health. Discuss why this/these horizontal linkages have promise for expansion. 4. What “horizontal linkages” (e.g. implementation research, drug discovery) does UCSF not have strengths which have potential for further expansion in to global health. Discuss why this/these horizontal linkages have promise for expansion. 5. What does UCSF lack in regards to disciplines important to global health, and what strategies could be used to improve multi/interdisciplinary collaboration?
  8. 8. Strategic Planning:Verticals, Horizontals
  9. 9. Take-Homes for Today’sConsideration: Meeting 1 The perception of a separation between that community and the clinical and translational research programs, especially as contained within the CTSI Supporting graduate student and post-doctoral fellow participation in global health research GHS needs to approach more basic scientists to further inquire about areas of need, resources and collaboration Education plays a central role in the potential expansion of global health research in the basic science community at UCSF Potential value in UCSF taking the lead in rebuilding the infrastructure of basic science laboratories at academic medical universities in resource limited settings Opportunity for scientists interested in global health to teach basic science abroad Pilot research grants directed at global health research proposals from early career stage investigators Partnerships with private industry in the Bay Area Oncology was seen as an area where UCSF could become an international leader. It was advocated as an important disease area with a high burden, with limited strength in many of our comparison universities
  10. 10. Take-Homes for Today’sConsideration: Meeting 2 Vigorously endorsed cross-disciplinary collaboration The “verticals” in the clinical research discussion were already quite evolved and well- funded Primary task was thought to fall on finding “horizontals” that will make a greater impact on the community (greater return on investment) Critical to bridge basic science and clinical and translational research more than we have done to date Education and training needs were also identified as crucial areas where investment could yield a great competitive advantage to our efforts Clear that many participants were meeting for the first time Vertical suggestions: Oncology, tobacco control, mental health NCD, maternal/child health Horizontal suggestions: Education and remote learning, health disparities, low cost point of care tests, pathology and lab medicine, ethical and legal issues in global research
  11. 11. Take-Homes for Today’sConsideration: Meeting 3 Most institutions have given up the vertical /horizontal model in the 70’s Since UCSF has a chance to build a new model, we should offer a “way of doing Global Health” that is different A key theme of UCSF is evidenced based medicine and rigorous science. These could be a central means of differentiating our global health research identity from competitor institutions. What made the UCSF response to HIV so effective? It worked because the trans-disciplinary collaborations worked well UCSF expertise in HIV/AIDs grew out of both the fundamental basic science of the university, and the ongoing active interaction of many people in many disciplines working on HIV issues Focus on building the infrastructure that facilitates the kind of interaction that made us HIV leaders.
  12. 12. Take-Homes for Today’sConsideration: Meeting 3 IRAC summarized as example of attempt to break down barriers and engage broader community in dialog aimed at identifying and reducing barriers to research conduct Create programs that think about positive outcomes in new ways, in which interventions do not have to be a set of numbers that often times does not tell us the whole story but set against a larger frame of health and culture. Orthopedics/trauma could be a vertical given vibrant program and limited external competition Education, clinical / research integration, humanitarian research and policy research proposed as possible “horizontal” linker. UCSF has content expertise, methodological expertise, expertise in a continuum of care (prevention thru treatment), expertise in participatory research and community building and engagement. We need to diffuse this expertise across disciplines, while addressing scalability Implementation science is important because it can identify gaps in care. UW has a PhD in implementation sciences aimed at operation efficiencies, where they use expertise from business and engineering schools to identify efficiencies. UCSF is a great discoverer. We just need to add in the pragmatism of Implementation science Policy is addressed at UCSF in pockets- and needs to be brought together. We need to build stronger links among ourselves and other disciplines
  13. 13. Where Next? Community of global health research large, broad, complex Strong desire to work together and decrease isolated efforts Suggestion to continue discussions with country, discipline etc. focus Broad agreement that education and training crucial HIV as model of cross-disciplinary collaboration Structure of GHS as it relates to entire global research effort evolving and needs clarification and communication
  14. 14. Improvement Opportunities Time-limited community discussions with regional or discipline focus Ongoing discussion group for concentrated programs (E. Africa) Support TAG for new funding opportunities and use RDO Convene administrative group to compare models, influence policies Work with departments re: promotion barriers for GH investigators

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