Successfully reported this slideshow.
We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. You can change your ad preferences anytime.

Maintaining or Improving your health status in CPA (Khaled Al-shair)

746 views

Published on

Khaled summarises why many people do not improve as much as they could while being treated for chronic pulmonary aspergillosis, what they can do to help themselves if they are not already doing it.

Published in: Health & Medicine
  • Be the first to comment

  • Be the first to like this

Maintaining or Improving your health status in CPA (Khaled Al-shair)

  1. 1. Support Meeting for Aspergillosis Patients LED BY GRAHAM ATHERTON SUPPORTED BY GEORGINA POWELL, DEBBIE KENNEDY & DEBORAH HAWKER NAC CENTRE MANAGER CHRIS HARRIS FACTORS EFFECTING HEALTH STATUS IN CHRONIC PULMONARY ASPERGILLOSIS LESSONS WE HAVE LEARNED BY DR KHALED AL-SHAIR NATIONAL ASPERGILLOSIS CENTRE UHSM MANCHESTERFungal Research Trust
  2. 2. Factors affect health status in Chronic pulmonary aspergillosis (CPA): lessons we have learned Dr Khaled Al-shair MD PhD National Aspergillosis Centre South Manchester University Hospital2
  3. 3. I’ve been told that my case is poor/very poor, can I get better?3
  4. 4. Patients gained therapeutic benefit irrespective of their illness severity where >50% of those who had “poor” and “very poor” at baseline improved with reduction of ≥4 scores after 6 months of treatment.4
  5. 5. Do all patients get improved?5
  6. 6. After treatment:- Approximately 70% responded, - Approximately 30% deteriorated after 6 months oftreatment,6
  7. 7. Important factors that affect response to anti-fungal treatment and overall health in CPA: 1. Underlying disease(s) 2. Precipitating factors eg., smoking, 3. Physical activity 4. Other factors A- Age B- Nutritional status C- Acute chest infections7
  8. 8. Underlying disease(s): Disease Frequency (n, (%) Previous classical tuberculosis 15 (17) Previous non- tuberculous 10 (11.4) mycobacterium infection Asthma 12 (13.6) ABPA 11 (12.5) COPD (± bullae) 33 (37.6) Previous pneumothorax 17 (19.3) Bronchiectasis 25 (28.4) Lung cancer survivor 9 (10.3) Pneumonia (with hospital 15 (17) admission) Sarcoidosis 5 (5.7) 8 Al-shair et al., Chest 2012 Felton et al., CID. 2010
  9. 9. Smoking effect on lung function:9 Fletcher & Peto Br Med J. 1977
  10. 10. 10
  11. 11. The importance of physical activity:11 Al-shair et al., Res. Med. 2009
  12. 12. Other Factors: Nutritional status Frequent Chest infections12
  13. 13. Thank you13
  14. 14. Thank You“The best chance we have of beating this illness is to work together” Living with it, Working with it, Treating it Fungal Infection Trust

×