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USES AND MODE OF ACTION AC

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USES AND MODE OF ACTION AC

  1. 1. USES AND MODE OF ACTION OF ACTIVATED CHARCOAL SEMINAR PRESENTED BY ONASANYA, IDOWU FRANCIS MATRIC NO: 115042086 SCIENCE LABORATORY TECHNOLOGY (HND II ENVIRONMENTAL BIOLOGY) SUPERVISED BY: MRS. V.T SANYAOLU
  2. 2. OUTLINE  Introduction  Objective  Uses of activated charcoal  General characteristics of activated charcoal  Mode of action of activated charcoal  Mechanism of absorption  Substances absorb by activated charcoal  Forms of activated charcoal  Mode of Administration  Safety of activated charcoal  Conclusion  Recommendation  References
  3. 3. INTRODUCTION Activated charcoal is a dark grey residue consisting of carbon and ash obtained by slow pyrolysis. (Timber, 2012) Activated charcoal is not the same as the regular charcoal. Activated charcoal is produced using steam or air at high temperature to oxidize charcoal in a controlled environment. (NHR, 2012)
  4. 4. Activated charcoal can adsorb thousands of its own weight in gases, toxic metals, poisons and other chemicals, thus making them ineffective or harmless. (Thrash et al, 1998) Today, Activated charcoal has been recommended by the poison control centers of America, including the animal poison control center because of its high value as a universal antidote (Bradberry and Vale, 1995)
  5. 5. OBJECTIVE  To discuss the uses and mode of action of activated charcoal.
  6. 6. USES OF ACTIVATED CHARCOAL TREATMENT OF AILMENTS SUCH AS •LIVER CANCER •HEART BURN stomach acid and irritating sub from food •PEPTIC ULCER(stomach acid(gastrin) ) •DENTAL INFECTION  TREATMENT OF WOUNDS (INJURY)
  7. 7. ANTIDOTE AGAINST; • POISON (PLANT TOXINS) • DRUG OVERDOSE (ASPIRIN,PARACETAMOL, COCAINE) • BEE STING • SNAKE BITE (VENOM) WATER PURIFICATION
  8. 8. PLATE 1: Red colobus monkeys eating activated charcoal. (Struhsaker et al, 1997)
  9. 9. GENERAL CHARACTERISTICS LARGE SURFACE AREA SMALL PORE SIZE HIGH ADSORPTION ABILITY Robert et al, 2012
  10. 10. PLATE 2: MECHANISM FOR ADSORTION IN ACTIVATED CHARCOAL (FRANCIS,2012) Activated charcoal is subjected to steam and oxygen, small pores are created. This pores are active at trapping chemicals, especially those that are not attracted to water such as organic compound. MODE OF ACTION OF ACTIVATED CHARCOAL
  11. 11. MECHANISM OF ABSORPTION Most xenobiotics are carbon based that may adhere to carbon compounds by chemical forces.  By supplying a large area of carbon surrounding the xenobiotics, are attracted to the carbon and the xenobiotics bind at a number of sites, effectively sticking to the charcoal. (American Academy of Clinical Toxicology, 1997)
  12. 12. SUBSTANCES ADSORBED BY ACTIVATED CHARCOAL Aspirin, Atropine, Chloroquine, Carbon dioxide, Congesprin, Dalmane, Darvon, Dilantin, Gasoline, Hemlock, Imipramine, Iodine, Ipecac, Kerosine, Lead Acetate, Malathion, Mercury, Methylene, Blue, Morphine, Multivitamins, Muscarin, Nacotics, Nacotine, Opium, Parathion, Penicillin, Pesticides, Phenol, Potassium Permanganate, Quinidine, Quinacrine, Radioactive substances, Herbicides. E.t.c Total Health Newsletter, 1998
  13. 13. FORMS OFACTIVATED CHARCOAL FRANCIS, 2013 PLATE 3:
  14. 14. PLATE: 4 ACTIVATED CHARCOAL FOR INDIGESTION FRANCIS,2013
  15. 15. MODE OF ADMINISTRATION ORAL TOPICAL
  16. 16. SCHEMATICDIAGRAMOFACTIVATEDCHARCOALGISYSTEMSHOWING XENOBIOTICSTRANSPORTSYSTEM Hill Healthcare publication, 1987 When activated charcoal is taken orally, it is dispersed throughout the digestive system, as it passes naturally through the digestive system. Substance are bound to the particles of activated charcoal forming complex. A large portion of the substance are adsorbed directly from the digestive system or blood vessel surrounding or supporting the digestive system, this process may occur by migration, secretion or diffusion. PLATE 5:
  17. 17. SAFETY OF ACTIVATED CHARCOAL Activated charcoal is simple to use and is a time-tested natural remedy that has many valuable uses  It has no dangerous side effects or contraindications, It is a very efficient cleaner of the body when taken orally and it also helps to purify the blood. (Kaufman, 2005) It is an odourless, tasteless, flavourless, powder but it texture is less appealing. (Medical world news, 1967)
  18. 18. CONCLUSION  Activated charcoal is an old natural remedy of medical proof.
  19. 19. RECOMMENDATION I join the pediatrician to recommend that every household should have some activated charcoal in their chest for first aid measure
  20. 20. REFRENCES  Richard C. Kaufman, Ph.D. THE UNIVERSAL ANTIDOTE AND DETOXIFIER THAT EXTENDS LIFE: ACTIVATED , Mega Health Society - July 1989.  Thrash, Agatha & Calvin Rx: Charcoal, New Lifestyle Books, 1998.  Tom Harrelson (Revised 4/17/08)An Article by HHR's Charles L. Church Published in Countryside Magazine  Donovan (1987) McGraw- Hill Healthcare publication  Palatnick W, Tenenbein M. Activated charcoal in the treatment of drug overdose. An update. Drug Safety 1992;7:3-7.  Bradberry SM, Vale JA. Multiple-dose activated charcoal: a review of relevant clinical studies. Journal of Toxicology - Clinical Toxicology 1995;33:407-416.  Chyka PA, Seger D. Position statement: single-dose activated charcoal. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists. J Toxicol Clin Toxicol 1997; 35(7):721-741.  Position statement and practice guidelines on the use of multi-dose activated charcoal in the treatment of acute poisoning. American Academy of Clinical Toxicology, European Association of Poisons Centres and Clinical Toxicologists. J Toxicol Clin Toxicol 1999; 37(6):731-751.  Bond GR. The role of activated charcoal and gastric emptying in gastrointestinal decontamination: a state- of-the-art review. Ann Emerg Med 2002; 39(3):273-286.
  21. 21. I APPRECIATE YOU ALL FOR LISTNING

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