2. +
The Newborn
APGAR
Calculated at 1 and 5 minutes
Appearance
Pulse
Grimace
Activity
Respiration
2
3. +
The Newborn
APGAR
1 minute reading
Tells how the newborn tolerated labor
5 minute reading
Tells the newborn’s response to resuscitation
Does NOT predict neurological outcome
3
5. +
The Newborn
On Physical Exam
Asymmetric Moro Reflex on a large for gestational
age infant and…
Left arm extended and medially rotated
Erb-Duchenne (C5-C6)
Refer if not better by 3-6 mo for neuroplasty
5
6. +
The Newborn
On Physical Exam
Asymmetric Moro Reflex on a large for
gestational age infant and…
Palpation of the clavicles shows crepitus
Clavicular fracture
6
13. +
The Newborn
On Physical Exam
Dermatologic findings
Nevus Sebaceous
Tx: Remove before adolescence
13
14. +
The Newborn
Neonatal Screening
Screening varies by state
Two disorders checked for in every state
Phenylketonuria
Deficient Phenylalanine Hydroxylase
Tx: Low phenylalanine diet
Galactosemia
Deficient G1P-uridyl-transferase
Tx: No lactose for life
14
15. +
The Newborn
Neonatal Jaundice
The following are scenarios designed to mimic patient
presentations in question stems
15
16. +
The Newborn
Yellow Babies
Three day old
Elevated Total Bilirubin and regular Direct Bilirubin
Baby is eating and pooping well!
Physiologic jaundice
Gone by 5th day
Liver conjugation not yet mature
16
17. +
The Newborn
Yellow Babies
Nine day old
Total Bilirubin less than 15 but Direct Bilirubin of 0.5
Dry mucous membranes and no weight gain
Breast feeding jaundice
Inadequate feeding = dehydration
Tx: Increase the number of feedings or duration
17
18. +
The Newborn
Yellow Babies
18 hour old
Elevated Total Bilirubin and Direct Bilirubin
No major complaints
Pathologic Jaundice
Jaundice under 24hr old is ALWAYS pathologic
Must rule out SEPSIS or other possible causes
Next best test: Coombs test
18
19. +
The Newborn
Yellow Babies
Eight day old
Normal Total Bilirubin but Markedly Elevated Direct Bilirubin
Dark urine with pale stool
Biliary atresia
Bile ducts cannot drain
Eventual liver failure
Increased liver function tests
Tx: Surgery
19
20. +
The Newborn
Yellow Babies
Jaundice’s major complication?
Kernicterus
Bilirubin deposits in the basal ganglia and
brain stem
Tx: for mild: Phototherapy
Tx: for severe: Double volume exchange transfusion
20
23. +
The Newborn
Respiratory Disorders
Diaphragmatic Hernia
Biggest Complication
Pulmonary hypoplasia
Best Tx:
If Dx prenatally use extracorporeal membrane oxygenation
to let lungs mature prior to surgery
23
25. +
The Newborn
Respiratory Disorders
TE Fistula
Best Dx Test:
Observation of a coiled feeding tube on CXR
Associated with:
VACTERL abnormalities
25
26. +
The Newborn
Respiratory Disorders
Choanal Atresia
Baby born with:
Cyanosis when feeding
Pink when crying
Associated with:
CHARGE syndrome
26
27. +
The Newborn
Respiratory Disorders
Neonatal Respiratory Distress Syndrome (NRDS)
Premature baby born with:
Dyspnea
High respiratory rate
Nasal flaring
Pathophysiology
Surfactant deficiency
Tx: 02 therapy with nasal CPAP
27
29. +
The Newborn
Respiratory Disorders
Transient Tachypnea of the Newborn (TTN)
Pathophysiology
Lung fluid not squeezed via vaginal birth
Tx: Oxygen therapy
29
30. +
The Newborn
Respiratory Disorders
Meconium Aspiration Syndrome
Baby born with:
Dyspnea
Low Oxygen saturation
Rupture of Membranes shows greenish-brown fluid
Next Best Step:
Intubate and suction
30
31. +
The Newborn
Respiratory Disorder Review
Diaphragmatic Hernia
Bowel sounds in thorax
Pulmonary hypoplasia
TE Fistula
Labored breathing
Coiled feeding tube on CXR
31
32. +
The Newborn
Respiratory Disorder Review
Choanal Atresia
Cyanotic when feeding Pink when crying
NRDS
Premature Babies
Surfactant deficiency
32
33. +
The Newborn
Respiratory Disorder Review
TTN
Occurs in LGA infants
Transient excess pulmonary fluid retention
Meconium Aspiration Syndrome
Rupture of Membranes yields a green-brown fluid
Tx: intubation and suction
33
34. +
The Newborn
GI Disorders
Gastroschisis
Defect lateral to the umbilicus
No sac covering GI contents
High maternal AFP
Complications:
Removal will lead to short gut syndrome
34
35. +
The Newborn
GI Disorders
Omphalocele
Defect in the midline
Sac covering GI contents
High maternal AFP
Associated with:
Trisomies
Beckwith-Wiedemann Syndrome
35
36. +
The Newborn
GI Disorders
Vomiting Babies
Pyloric Stenosis
Non-bilious and projectile
Palpable olive mass
Hypochloremic, hypokalemic, metabolic alkalosis
Tx:
Stabilize electrolyte imbalance
Surgical myotomy
36
37. +
The Newborn
GI Disorders
Vomiting Babies
Intestinal Atresia
Bilious
Pregnancy complicated by POLYhydramnios
Associated with Down’s
Tx:
Surgery
37
38. +
The Newborn
GI Disorders
Vomiting Babies
Malrotation and volvulus
Bilious
Baby draws legs towards abdomen
Abdominal distention
38
39. +
The Newborn
GI Disorders
Vomiting Babies
Malrotation and volvulus
Pathophysiology
Gut does not rotate fully around the superior
mesenteric artery (SMA)
Tx:
Surgery
39
40. +
The Newborn
GI Disorders
Pooping Problems
Meconium ileus
Delayed passage of meconium
Consider association with Cystic Fibrosis
Tx:
Gastrograffin enema is both Dx and Tx
40
41. +
The Newborn
GI Disorders
Pooping Problems
Hirschsprung’s Disease
Failure of neural crest cells migration
Explosion of meconium on digital rectal exam
Rectal biopsy is GOLD STANDARD for Dx
No ganglia present
41
42. +
The Newborn
GI Disorders
Pooping Problems
Necrotizing Enterocolitis
Common in prematurity
Bloody diarrhea
Pneumocystis intestinalis seen on x-ray
Tx:
Nil per os “nothing per mouth”
Total parenteral nutrition
Antibiotics and possible resection of necrotic bowel
42
43. +
The Newborn
GI Disorders
Pooping Problems
Intussusception
Currant jelly stool
Sausage shaped mass in Right Upper Quadrant
Colicky abdominal pain
Tx:
Barium enema
43
44. +
The Newborn
GI Disorder Review
Gastroschisis
Defect lateral to the umbilicus
No sac covering GI contents
Omphalocele
Defect in the midline
Sac covering GI contents
44
45. +
The Newborn
GI Disorder Review
Pyloric Stenosis
Palpable olive mass
Hypochloremic, hypokalemic, metabolic alkalosis
Intestinal Atresia
Pregnancy complicated by POLYhydramnios
Associated with Down’s Syndrome
45
46. +
The Newborn
GI Disorder Review
Malrotation and volvulus
Bilious Vomiting
Baby draws legs towards abdomen
Meconium ileus
Delayed passage of meconium
Consider association with Cystic Fibrosis
46
47. +
The Newborn
GI Disorder Review
Hirschsprung’s Disease
Failure of neural crest cells migration
Rectal biopsy is GOLD STANDARD for Dx
Necrotizing Enterocolitis
Common in prematurity
Bloody diarrhea
47
48. +
The Newborn
GI Disorder Review
Intussusception
Currant jelly stool
Sausage shaped mass in Right Upper Quadrant
48
49. +
The Newborn
GU Disorders
Cryptorchidism
Male with no palpable testes
Usually found in the inguinal canal
Next best step: Ultrasound to confirm
Tx: Surgery if not descended by one year
49
54. +
The Newborn
Neonatal Fever
Sepsis
Most common causes:
Group B Strep
E. Coli
Lysteria monocytogenes
Empiric Tx:
Ampicilin and gentamycin until 48 hr CXR are negative
54
60. +
The Newborn
Conjunctivitis
First – Third Day of Life
Chemical conjunctivitis
Red and tearing
Caused by silver nitrate drops
Uncommon because erythromycin now used
60
61. +
The Newborn
Conjunctivitis
Third – Fifth Day of Life
Gonococcal conjunctivitis
Bilateral purulent discharge
Can cause corneal ulceration
Tx:
Topical erythromycin
IV 3rd generation cephalosporin
61
62. +
The Newborn
Conjunctivitis
Seventh Day – 2nd Week of Life
Chlamydia conjunctivitis
Red conjunctiva
Mucoid discharge
Lid swelling
Can cause chlamydial pneumonia
Tx:
Oral Erythromycin
62