CIHR factsheet - Personalised Medicine


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CIHR factsheet - Personalised Medicine

  1. 1. CIHR Personalized Medicine InitiativeIntroduction choices to individual patient characteristics.The CIHR Institute of Cancer Research, Institute of Genetics, and 3) To foster the development and validation of diagnosticsInstitute of Health Services and Policy Research, in partnership based on such biomarkers, targets and genomic signatures, andwith several CIHR institutes, and in close consultation with of innovative devices for the application to patient practice.provincial and federal funders, are leading a new strategic initiativein Personalized Medicine. The goal of this initiative is to engage Developing a National Researchbiomedical, clinical, population health, health economics, ethics Agendaand policy researchers, as well as provincial health authorities, in The proposed initiative will build on significant Canadianan undertaking to identify health care burdens in disease that are strengths in discovery research, clinical trials, biomarkers, andsuitable for a personalized medicine approach. This initiative will nanotechnology. It will also build on Canada’s strong existingultimately support translational research for the effective infrastructure, including genome centers, large-scale cohortprevention, diagnosis, and treatment of disease. studies, and tissue/tumor/serum banks. This initiative will engage provincial health authorities, multiple funding parties,Scope of Personalized Medicine clinicians and researchers to develop a personalized medicinePersonalized medicine promises to transform the delivery of pipeline to enable effective policy leading to preventativehealthcare to patients. Healthcare will evolve from a reactive “one- interventions as well as molecular, evidence-based medicinesize-fits-all” system towards a system of predictive, preventive, to the health care system.and precision care. Personalized medicine will not only focus on the identification of Partnerships biomarkers and This personalized medicine initiative will interface with genetic signatures CIHR’s Strategy on Patient-Oriented Research, as well as with for prevention and other existing and developing CIHR initiatives. We are prediction of working in close collaboration with provincial and federal therapeutic response, funders to develop a coordinated approach. Workshops but will also enhance scheduled for 2011 will engage provincial health authorities, awareness about Health Canada, voluntary health organizations, researchers in lifestyle and biomedical, clinical, health services, and policy research, preventive lifestyle provincial funders, and others, to foster a dialogue on a changes. Areas in national health research agenda that will address pressing which personalized priorities relevant to personalized medicine. The aim of these approaches are workshops is to identify gaps and priorities in personalized particularly medicine and to develop a national framework forpromising include oncology, cardiovascular diseases, personalized medicine. We also hope to engage other potentialneurodegenerative diseases, psychiatric disorders, diabetes and partners and seek their expertise to further enhance thisobesity, arthritis, pain, and Alzheimer’s disease. In all of these initiative.fields, and others, a personalized molecular medicine approach isexpected to lead to better health outcomes, improved treatments, Contact Informationand reduction in toxicity due to variable or adverse drug responses. Dr. Morag Park / Dr. Inga Murawski CIHR Institute of Cancer ResearchObjectives Dr. Paul Lasko / Ms. Stephanie RobertsonThe specific objectives of the Personalized Medicine Initiative are: CIHR Institute Genetics1) To develop an evidence base on how to assess and, where Dr. Robyn Tamblyn / Ms. Maude Ruest Archambaultappropriate, integrate innovative diagnostics (including laboratory CIHR Institute of Health Services and Policy Research Canadian Institutes of Health Researchdiagnostics and medical imaging) into health policy and practice. 160 Elgin Street, 9th Floor, Address Locator 4809A2) To stimulate the discovery, validation, and translation of Ottawa, Ontario K1A 0W9 Canadabiomarkers, targets and genomic signatures for risk prevention and Tel: 514-398-2981for diseases, which have the potential to improve the outcomes of inga.murawski@mcgill.catherapeutic interventions by selecting tailoring of treatment