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Infographic: The Opioid Epidemic in America

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The past 50 years have seen a growing epidemic of opioid addiction and abuse emerge in the United States.

Both opioids and the current epidemic have long been a focus of scientific research; with Scopus® data from 2011-2016, we used SciVal to analyze scholarly output, research impact, trending topics, and top researchers on both topics. You can find more information and data here: https://www.elsevier.com/research-intelligence/campaigns/the-opioid-epidemic-in-america

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Infographic: The Opioid Epidemic in America

  1. 1. All data taken from SciVal or Scopus on May 31, 2017. Scopus® data from January 1, 1950 to December 31, 2016 and includes all publication types (articles, papers, surveys, reviews, editorials, etc.) where search terms were mentioned in the title, abstract, or keywords. © 2017 Elsevier B.V. All rights reserved. SciVal is a trademark of RELX Intellectual Properties SA. About SciVal SciVal offers quick, easy access to the research performance of 8,500 research institutions and 220 countries worldwide. For more information, visit scival.com. About Scopus Scopus® is the world’s leading abstract and citation database, and is used by institutions, governments, as well as for university rankings around the world. For more information, visit scopus.com. Global USA The Opioid Epidemic in America The Research Behind Understanding, Preventing and Treating Addiction Research Referencing Opioids (1950-2015) Top Journals Worldwide, research referencing opioids in any context increased by a factor of 54 between 1950 and 20152 Based on number of publications referencing opioids Anesthesia & Analgesia 4,242 publications European Journal of Pharmacology 3,348 publications Anesthesiology Journal 2,983 publications British Journal of Anaesthesia 2,970 publications Journal of Pharmacology & Experimental Therapeutics 2,962 publications The past 50 years have seen a growing epidemic of opioid addiction and abuse emerge in the United States; in 2015 alone, opioid medications, both legal and illegal, caused over 30,000 fatalities, triple the number of overdoses reported the entire 15 years prior.1 Both opioids and the current epidemic have long been a focus of scientific research; with Scopus® data from 2011-2016, we used SciVal to analyze scholarly output, research impact, trending topics, and top researchers on both topics. Request more information on SciVal Research output referencing opioids, 1950-2015 497 89161 163 179 212 258 237 228 213 213 194 214 236 467 659 477 546 640 663 733 856 2231 273928002810 2991 3360 3833 4467 4,652 3874 4151 4340 4458 3754 39023976 4528 4350 4564 4833 5255 5056 5213 5274 5271 5407 5870 6422 7357 7720 8172 8118 8315 8184 8246 8435 8704 9086 8480 25 20 26 32 19 33 32 39 33 37 48 45 69 100 79 89 119 104 113 179 761 1122 1167 1163 1152 1251 1417 1713 1,817 1447 1578 1644 1554 1329 14601491 1642 1556 1680 200720592030 21012095 1992 1991 2102 2284 2717 2852 3029 2882 3020 289029623022 3204 3326 3288 Publications 0 2,000 4,000 6,000 8,000 10,000 1950 1951 1952 1953 1954 1955 1956 1957 1958 1959 1960 1961 1962 1963 1964 1965 1966 1967 1968 1969 1970 1971 1972 1973 1974 1975 1976 1977 1978 1979 1980 1981 1982 1983 1984 1985 1986 1987 1988 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 1,013 221 2,726 1,088 8734 3161 8,047 3,045 5,843 2,020 155 24
  2. 2. 1) Rudd, R. A., Seth, P., David, F., & Scholl, L. (2016). Increases in Drug and Opioid-Involved Overdose Deaths — United States, 2010–2015. MMWR. Morbidity and Mortality Weekly Report, 65 (5051), 1445-1452. doi:10.15585/mmwr.mm655051e1 2) Search performed in Scopus using the following terms: “opioid, opiate, fentanyl, hydrocodone, oxycodone, oxymorphone, propoxyphene, hydromorphone, meperidine, pethidine, diphenoxylate, methadone, morphine, or codeine“ 3) National Institute on Drug Abuse. (2017). Opioid Crisis. Retrieved May, 2017, from https://www.drugabuse.gov/drugs-abuse/opioids/opioid-crisis 4) Search performed in Scopus using the following terms: “opioid, opiate, fentanyl, hydrocodone, oxycodone, oxymorphone, propoxyphene, hydromorphone, meperidine, pethidine, diphenoxylate, methadone, morphine, codeine, or heroin”, AND "addiction, 'use disorder,' misuse, or overdose" Data from the U.S. National Institute on Drug Abuse indicates:3 Research Referencing Opioid Addiction (1950-2016)4 Scholarly output focused on opioid addiction represents a fraction of all research referencing opioids, with a particularly noticeable spike between 1969 and 1974: The most prolific institutions focused on opioid addiction, use disorder, misuse & overdoses over the last 65 years are largely from the United States: Research focused on treatment and prevention of opioid addiction show frequently occurring keyphrases include: pain management, opioid antagonists (such as naloxone), prescription drug misuse, and opioid substitution treatment. SciVal’s word cloud previews the growing (orange) and declining (blue) keywords and phrases found in this research area. The Opioid Epidemic in America The Research Behind Understanding, Preventing and Treating Addiction Roughly 21-29%of patients prescribed opioids for chronic pain misuse them Between 8-12%develop an opioid use disorder An estimated 4-6%who misuse prescription opioids transition to heroin Approximately 80%of people who use heroin first misused prescription opioids Publications 1950-2016 1,107 669 586 536 471 446 438 420 408 404 Institution VA Medical Center Yale University School of Medicine National Institute on Drug Abuse Harvard Medical School King's College London University of Pennsylvania The Johns Hopkins School of Medicine University of California, San Francisco University of California, Los Angeles University of New South Wales Analgesics, Opioid Methadone Buprenorphine HeroinTherapeutics Substance-Related Disorders Opioid-Related Disorders Opiate Substitution Treatment Pharmaceutical Preparations Pain Chronic Pain Heroin Dependence Naloxone Prescriptions Morphine PatientsNaltrexone Alcohols Cocaine Narcotic Antagonists Drug Users Drug Overdose Street Drugs Pain Management Maintenance Prescription Drugs CannabisHIV Receptors, Opioid, mu Cocaine-Related Disorders Substance Withdrawal Syndrome Prescription Drug Misuse Narcotics Morphine Dependence Risk Reward Oxycodone Methamphetamine Substance Abuse Detection Comorbidity Harm Reduction Injections Primary Health Care Opioid Misuse & Addiction in the United States Percentage of all opioid-referencing research focused on addiction, 1950-2016 0 10% 20% 30% 40% 50% 1950 1953 1956 1959 1962 1965 1968 1971 1974 1977 1980 1983 1986 1989 1992 1995 1998 2001 2004 2007 2010 2013 2016 Country US US US US UK US US US US AUS

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