Sallie Goetsch provides an overview of the pros, cons, and particularly ease of use of three WordPress themes/frameworks designed to let you create a site "without knowing code"--which is definitely not the same as "without knowing anything." Make from Theme Foundry is simplest (and free); Headway is the most drag-and-drop, since you draw elements on a grid. Ultimatum has the biggest learning curve, though it seems as though you could create nearly anything with it once you were familiar with the way it worked.
Pieter Hartsook's demonstration of Divi from Elegant Themes (not included with these slides) eclipsed all of them due to the number of pre-defined templates and low price of that theme.
From the June 20th, 2014 East Bay WordPress Meetup