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The Systematic  Literature Search   Andrea Chapman Workshop Systematic Reviews March 11, 2009
Overview   ,[object Object],[object Object],[object Object],[object Object]
The Systematic Literature Search   ,[object Object],[object Object],[object Object],[object Object]
The Primary Search  ,[object Object],general specific
Further Phases ,[object Object],[object Object]
Search   Steps  clinical / PICOTS question search strategy search databases collect results
Adjusting the Question clinical / PICOTS question search strategy search databases collect results
PICOTS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Example Question ,[object Object],[object Object],[object Object]
Example Question ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Developing the Search Strategy  clinical / PICOTS question search strategy search databases collect results
Boolean Logic  ,[object Object],[object Object],[object Object]
Boolean Logic  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Combing Terms ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Special Characters  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Basic Search String  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Expanding the Basic Search ,[object Object],other ? other ? other ?
Expanding the Basic Search ,[object Object]
clinical / PICOTS question search strategy search databases collect results
Searching Pubmed
PubMed and the Search Strategy search strategy search PubMed
PubMed Search ,[object Object]
PubMed Features ,[object Object],[object Object],[object Object],[object Object]
Enter the search  term and press  Go .
[object Object],Search a  second term.
View the  History
Combine  searches using  number in the History. doxycycline
Limit  searches.
Limits ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Result!
clinical / PICOTS question search strategy search databases collect results
Can We Do Better? ,[object Object],MeSH term ? MeSH term ? MeSH term ?
MeSH - Medical Subject Headings  ,[object Object],[object Object],[object Object]
Example MeSH term  ,[object Object]
MeSH in PubMed  MeSH Gingival Hemorrhage is under  MeSH Periodontal Disease! hierarchy broader terms above specific terms
MeSH in PubMed Medications can  also be a MeSH term.
Example MeSH term  ,[object Object],Use MeSH term Use MeSH term Use free text Unnecessary ?
Access the MeSH database  from PubMed.
MeSH Features  ,[object Object],[object Object],[object Object],[object Object]
Send MeSH term  to search box.
The MeSH term is  now in the search box.
When more than one  MeSH term is found. Double click.
Complete Search String  ,[object Object]
Complete Search String  ,[object Object],("Periodontal Diseases"[Mesh] OR parodontos*)  AND ("Doxycycline"[Mesh] OR vibramycin) AND ("Gingival Hemorrhage"[Mesh] OR "gum bleeding") ("Periodontal Diseases"[Mesh] OR parodontos*) AND ("Doxycycline"[Mesh] OR vibramycin) AND ("Gingival Hemorrhage"[Mesh] OR  " gum bleeding " )
PubMed - Additional Features  ,[object Object],[object Object],[object Object]
Click  Details  to see how  Pubmed interpreted results
Pubmed mapped gum bleeding  to the MeSH term  gingival hemorrhage
Clear  searches.
To Export  go into Result
www.pubmed.com
Searching Cochrane ,[object Object],[object Object],[object Object],[object Object],[object Object]
www.thecochranelibrary.com
Document the Search Strategy  ,[object Object],[object Object],[object Object]
clinical / PICOTS question search strategy search databases collect results
EndNote ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Importing
Importing
Change Field  Content
Rename Field  Headings
The Systematic Literature Search

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The Systematic Literature Search

Editor's Notes

  1. In the first part, I will discuss what a systematic literature searches is and why we conduct them. Then I will show you how to develop search strategies and conduct searches. We will look at some examples to learn how to do this in practice. At the end of the day, we will develop the search strategy, conduct the search and collect results for the Bach Flower Remedy.
  2. What: a systematic approach to search for literature Why: minimize bias Should be: thorough, objective and reproducible How: often conducted in several phases, using various sources
  3. The, what I would call, main three databases that we search are PubMed, Cochrane, and EMBASE. Access to PubMed free and it contains Medline citations. (Medical Literature Analysis and Retrieval System Online) is the U.S. National Library of Medicine's premier bibliographic database that contains over 16 million references to journal articles in life sciences with a concentration on biomedicine. In some cases, specialized databases should be searched. For example, if the question deals with a drug intervention, a pharmaceutical database should be searched. Since our topic, Bach Flower Remedies, falls within complementary medicine, we will also search AMED.
  4. Two phases of the literature search which will not be addressed today are the grey literature search and the manual literature search. The grey literature search is a search for publications not published commercially or indexed by major databases. The manual search is the final phase of the literature search. In the 4. session I will come back to the manual search.
  5. If necessary, the concepts included in the question should be discussed with reviewers.
  6. If necessary, the concepts included in the question should be discussed with reviewers.
  7. Begin either with a clinical question and use it to form a PICOTS question or begin with a PICOTS question. The PICOTS structure is especially suitable to the literature search because it identifies the main concepts and indicates how the concepts are related. ---HANDOUT----
  8. Begin either with a clinical question and use it to form a PICOTS question or begin with a PICOTS question. The PICOTS structure is especially suitable to the literature search because it identifies the main concepts and indicates how the concepts are related. ---HANDOUT----
  9. Begin either with a clinical question and use it to form a PICOTS question or begin with a PICOTS question. The PICOTS structure is especially suitable to the literature search because it identifies the main concepts and indicates how the concepts are related. ---HANDOUT----
  10. If necessary, the concepts included in the question should be discussed with reviewers.
  11. * Zahnfleisch The terms are read from left to right. Do NOT use NOT in a systematic review!!
  12. Again, terms are read from left to right.
  13. Some special characters vary from database to database. Take care with Latin roots (e.g. pharma). American / British spelling. Hypens not readable in EMBASE. Use OR for pluralization.
  14. If necessary, the concepts included in the question should be discussed with reviewers.
  15. If necessary, the concepts included in the question should be discussed with reviewers.
  16. Each articles is read by two experts in the specific area who assign the article MeSH terms.
  17. Each articles is read by two experts in the specific area who assign the article MeSH terms.
  18. Each articles is read by two experts in the specific area who assign the article MeSH terms.
  19. Why use free text and MeSH
  20. Why use free text and MeSH
  21. Why use free text and MeSH
  22. I would recommend to create a word document and save it in the project folder under a folder called “Literature Search”.
  23. If necessary, the concepts included in the question should be discussed with reviewers.