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Dutch Incubation Forum / The Hague / 11.12.2014/@unitystoakes 
The Re-imagination of Healthcare
“There has never been a 
better time to be a 
healthcare innovator” 
@unitystoakes
The Creative Destruction of Healthcare 
@unitystoakes 
TRANSFORMED INDUSTRIES 
Media 
Entertainment 
Music 
Travel 
Retail...
The Conditions Are Set for an Epic Decade 
@unitystoakes 
Opportunity 
The Golden Age of 
Entrepreneurship 
Change 
Health...
x 
= 
Healthcare Transformers 
The Network Effect 
The Re-imagination of Healthcare 
@unitystoakes 
TM & © 2014 STARTUP HE...
5 Transformation Requirements: 
! 
1. Army of Entrepreneurs 
2. The Network Effect 
3. Unique Stakeholder Partnerships 
4....
Building an Army of 
Entrepreneurs to Reinvent 
@unitystoakes 
Healthcare
@unitystoakes 
10 
years 
1,000 
100,000 
healthcare startups 
innovators 
TM & © 2014 STARTUP HEALTH, LLC. ALL RIGHTS RES...
A New Model for Accelerating Innovation 
@unitystoakes 
StartUp Health 
3 Year Academy 
Coaching Program 
StartUp Health 
...
An International Program & Growing Community 
84 COMPANIES FROM 7 COUNTRIES AND MORE THAN 45 CITIES 
UNITED STATES • AUSTI...
Calling All Changemakers 
@unitystoakes 
~ 
Use Your Talent to 
Transform Healthcare! 
www.startuphealth.com 
unity@startu...
@unitystoakes 
Appendix
Insights and Trends 
2014 is shaping up to be another record year for digital health, with funding in the first three quar...
Insights and Trends 
14 
9 High Deductible Plans: People no longer outsourcing health decisions to employer, government, d...
Insights and Trends 
15 
17 Hospitals of the Future - Everywhere: Care shifting outside of hospital to home, clinics, hubs...
INVESTORS MOMENTUM 
DIGITAL HEALTH FUNDING SNAPSHOT (YTD) 
600 
450 
300 
Source: StartUp Health Insights | www.startuphea...
DEALS & FUNDING 
THE TOP 10 MOST ACTIVE SUBSECTORS OF 2014 (YTD) 
Big data is clearly a big winner. Even if companies don’...
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Unity Stoakes Startup Health - dif14 - 12-11-14

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Startup Health creert een eigen categorie business incubators. In 10 jaar tijd wil zij 1.000 startup wereldwijd verbinden aan de uitdaging om de gezondheidszorg dramatisch te vernieuwen. Een waar 'Global Entrepreneurship' aanpak, die het ambitieniveau van Amerikaanse ondernemers weergeeft.

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Unity Stoakes Startup Health - dif14 - 12-11-14

  1. 1. Dutch Incubation Forum / The Hague / 11.12.2014/@unitystoakes The Re-imagination of Healthcare
  2. 2. “There has never been a better time to be a healthcare innovator” @unitystoakes
  3. 3. The Creative Destruction of Healthcare @unitystoakes TRANSFORMED INDUSTRIES Media Entertainment Music Travel Retail/Commerce Healthcare “Creative Destruction” popularized by Joseph Schumpeter in Capitalism, Socialism and Democracy. Richard Foster and Sarah Kaplan applied the concept directly to healthcare in Creative Destruction. Dan Sullivan and The Strategic Coach simplified the concept further in his Creative Destruction Series. Eric Topol, MD, recently wrote a book The Creative Destruction of Medicine. TM & © 2014 STARTUP HEALTH, LLC. ALL RIGHTS RESERVED.
  4. 4. The Conditions Are Set for an Epic Decade @unitystoakes Opportunity The Golden Age of Entrepreneurship Change Healthcare Reform Technology Mobile & Digital Health Acceleration Chronic Disease, Aging & Cost TODAY TM & © 2014 STARTUP HEALTH, LLC. ALL RIGHTS RESERVED.
  5. 5. x = Healthcare Transformers The Network Effect The Re-imagination of Healthcare @unitystoakes TM & © 2014 STARTUP HEALTH, LLC. ALL RIGHTS RESERVED.
  6. 6. 5 Transformation Requirements: ! 1. Army of Entrepreneurs 2. The Network Effect 3. Unique Stakeholder Partnerships 4. Global Cross-Pollination 5. Batteries Included Leaders @unitystoakes
  7. 7. Building an Army of Entrepreneurs to Reinvent @unitystoakes Healthcare
  8. 8. @unitystoakes 10 years 1,000 100,000 healthcare startups innovators TM & © 2014 STARTUP HEALTH, LLC. ALL RIGHTS RESERVED.
  9. 9. A New Model for Accelerating Innovation @unitystoakes StartUp Health 3 Year Academy Coaching Program StartUp Health Network Healthcare Transformers Investors, Startups, Partners, Customers, Government Growing Community of Entrepreneurs and Innovations Transforming Healthcare TM & © 2014 STARTUP HEALTH, LLC. ALL RIGHTS RESERVED.
  10. 10. An International Program & Growing Community 84 COMPANIES FROM 7 COUNTRIES AND MORE THAN 45 CITIES UNITED STATES • AUSTIN • BALTIMORE • BOSTON • CHICAGO • COLUMBUS • DENVER • DETROIT FORT LAUDERDALE • GREEN BAY • HOUSTON • KANSAS CITY • LONG BEACH • MALIBU • MIAMI NEW YORK CITY • PALO ALTO • PHILADELPHIA • PITTSBURGH • PORTLAND • SALT LAKE CITY SAN FRANCISCO • SAN JOSE • SEATTLE • WASHINGTON, DC • BRAZIL • PONTA GROSSA • RIO DE JANEIRO • CANADA • CALGARY • TORONTO • VANCOUVER • INDIA • BANGALORE • IRELAND DUBLIN • GALWAY • ISRAEL • ASHKELON • SPAIN • BARCELONA • PAMPLONA CONFIDENTIAL OCTOBER 2014 10
  11. 11. Calling All Changemakers @unitystoakes ~ Use Your Talent to Transform Healthcare! www.startuphealth.com unity@startuphealth.com
  12. 12. @unitystoakes Appendix
  13. 13. Insights and Trends 2014 is shaping up to be another record year for digital health, with funding in the first three quarters already far exceeding the total amount invested in 2013. Our quarterly report gives a snapshot of the sector’s “top 10” (give or take) investors, subsectors, deals and more. Here are eight trends we’re watching: 13 1 2014 Funding Reaches Record Levels: Through Q3, 347 companies have raised $5B from investors including Founders Fund, Khosla Ventures and Sequoia Capital. 2014 is on track to nearly double the total invested in 2013. 2 Deal Sizes Increase: Investment size continues to climb as the market matures and more private equity firms pour capital into the sector. As startups raise more cash, speculation is also building about the next wave of IPOs. 3 M&A Activity Picks Up: Even though summer activity tends to be slow, Q3 saw 15 acquisitions by companies including Google, Practice Fusion, Cerner and WebMD/Medscape. 4 ACA Spurs Innovation: Health reform continues to drive changes in the industry and encourages startup activity in the sector. 5 Consumerism Grows: As a result of high-deductible plans, price transparency and new tech solutions, patients are becoming more empowered. Brands like Apple, Facebook and Google are making bigger waves in healthcare. 6 Privacy Concerns Mount: As the Apple iCloud hacking scandal underscored, keeping health data safe in the cloud is becoming more top-of-mind for consumers and companies. 7 Wearables Move Into the Mainstream: We’re not there yet, but the debut of the Apple Watch, Basis Peak, Moto 360 and Samsung Gear Live show that wearables are clearly moving closer to the mainstream. 8 Global Innovation Accelerates: More than 5,000 startups around the world are developing new solutions in digital health, based on data from the StartUp Health Network. Increased % of revenue outside of US.
  14. 14. Insights and Trends 14 9 High Deductible Plans: People no longer outsourcing health decisions to employer, government, doctor. Consumers paying attention to price now that they are responsible and sharing risk. 10 Transparency: . Consumers demanding price transparency and host of new solutions entering market to deliver. Currently 400% price variance on certain procedures / drugs. 11 New Customers: 25 Million Americans gaining health insurance in next 3 years. New customers. 8,000 Americans eligible for medicare each day. 12 Analytics to Outcomes: Growing demand for predictive modeling….analytics to drive outcomes…precision medicine. becoming reality. Emerging new solutions entering market everyday. 13 Service and “Retail” Health Solutions: . Pharma repositioning beyond pill to become service companies. Delivery moving to retail environments. 14% growth….$1.4T vs. hospital growth of 2%. 14 Corporate Venture: From 10% to 35% of early stage funding in last 2 years shifted from VCs to corporate venture. 15 Consolidation: Massive provider consolidation due to intense reimbursement and cost pressure. 16 Chronic Disease: Primary patient demand driven by chronic disease…but wellness, prevention market emerging.
  15. 15. Insights and Trends 15 17 Hospitals of the Future - Everywhere: Care shifting outside of hospital to home, clinics, hubs, urgent care, etc.. 18 Home Health: . Home care becoming the center of the universe. Hundreds of new companies being created to deliver home care. 19 Leadership Turnover: Wave of management changes.…new leaders and others riding out tenure. 20 Rise of the Machines: Artificial intelligence coming to healthcare. Watson just the beginning… 21 Sensors on / in Everything: . Connected health….driving need for better data analytics. 22 New Frontier: The Brain: Brain health opening up world of innovation as significant as genomics revolution. 23 Early Stage Boom: More than 100 Healthcare accelerators, 5,000 startups…talk of bubble. Some models working.others not… 24 New Entrants: Who is the healthcare company future? Every company becoming healthcare co…matter of productivity, bottom line.. huge growth opp for small, medium, large businesses. Competition from everywhere..
  16. 16. INVESTORS MOMENTUM DIGITAL HEALTH FUNDING SNAPSHOT (YTD) 600 450 300 Source: StartUp Health Insights | www.startuphealth.com/insights Disclosure: Information, data and figures represent publicly available data. © 2014 StartUp Health, LLC 16 Funding ($B) $5B $4B $3B $1B Deals 150 2010 2011 2012 2013 YTD 2014 Deals Funding $5.0B $2.8B $2.2B $1.7B $1.1B 347 533 447 242 142 DEALS & FUNDING Funding in the first three quarters of the year has skyrocketed past the total invested in 2013. Although deal volume is lower, investors are putting more money in fewer startups, indicating the market’s gradual maturation.
  17. 17. DEALS & FUNDING THE TOP 10 MOST ACTIVE SUBSECTORS OF 2014 (YTD) Big data is clearly a big winner. Even if companies don’t primarily identify with the subsector, they’re encouraged to show a big data and analytics play to attract investor support. Source: StartUp Health Insights | www.startuphealth.com/insights Disclosure: Information, data and figures represent publicly available data. © 2014 StartUp Health, LLC 17 Subsector $ Invested # of Deals Largest Deals 1 Big Data / Analytics $1.17B 77 • Flatiron Health • Alignment Healthcare 2 Navigating the Care System $794M 40 • Preventice • Oscar 3 Practice Management $598M 26 • Privia Health • Zenefits 4 Sensors / Diagnostics $498M 25 • NantHealth • Flatiron Health 5 Patient Engagement $440M 38 • Preventice • One Medical 6 Consumer Health $439M 46 • Zenefits • Bswift 7 Insurance $381M 9 • Oscar • Zenefits 8 Vital Sign Monitoring $284M 17 • Proteus Digital Health • Omada Health 9 Aging with Vitality $242M 14 • NantHealth • Audax Health 10 Genomics $200M 14 • Human Longevity • Quantapore Note: Investments in the above subsectors are not mutually exclusive as deals are tagged with multiple subsectors. INVESTORS MOMENTUM

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