Unsupervised Identification of Study Descriptors in Toxicology Research: An Experimental Study

Dasha Herrmannova
Dasha HerrmannovaResearch Scientist at Oak Ridge National Laboratory
Unsupervised Identification of Study Descriptors in
Toxicology Research: An Experimental Study
Drahomira Herrmannova, Steven Young, Robert Patton, Chris Stahl, Nicole Kleinstreuer, Mary Wolfe
Study descriptors
Female weanling rats
Six rats per group
Four treatment groups
✓
✗
VS.
1. Goal: extraction of study descriptors from toxicology papers
2. Problem: lack of detailed annotations for training
3.
Present study: Can we use semantic similarity
to identify relevant text segments?
Natural-language
description of sought-
after information
Animal model: OVX adult rats
(OVX 6-8 weeks), 14 day
post-surgery recovery. OVX
adult mouse, …
Text segments from
target document
Segment 1 similarity: 0.5478
Segment 2 similarity: 0.3887
Segment 3 similarity: …
Segment 1: Pre-pubertal (day 18 of
life) female mice were …
Segment 2: The dosages of CTX
used were based on previous …
Segment 3: …
1 of 1

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Unsupervised Identification of Study Descriptors in Toxicology Research: An Experimental Study

  • 1. Unsupervised Identification of Study Descriptors in Toxicology Research: An Experimental Study Drahomira Herrmannova, Steven Young, Robert Patton, Chris Stahl, Nicole Kleinstreuer, Mary Wolfe Study descriptors Female weanling rats Six rats per group Four treatment groups ✓ ✗ VS. 1. Goal: extraction of study descriptors from toxicology papers 2. Problem: lack of detailed annotations for training 3. Present study: Can we use semantic similarity to identify relevant text segments? Natural-language description of sought- after information Animal model: OVX adult rats (OVX 6-8 weeks), 14 day post-surgery recovery. OVX adult mouse, … Text segments from target document Segment 1 similarity: 0.5478 Segment 2 similarity: 0.3887 Segment 3 similarity: … Segment 1: Pre-pubertal (day 18 of life) female mice were … Segment 2: The dosages of CTX used were based on previous … Segment 3: …