Ebm glossary therapy

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Ebm glossary therapy

  1. 1. Evidence Based Medicine Dr. Faisal M. Al Haddad Consultant of Family Medicine & Occupational Health PSMMC
  2. 2. Terms used in therapeutics Confounder: a factor that distorts the true relationship of the study variable of interest by virtue of also being related to the .outcome of interest Randomized Allocation: allocation of individuals to groups by .chance Concealment: concealment of allocation to study group assignments from those responsible for assessing patients .for entry in the trial Examples:  Sequentially numbered, opaque, sealed envelopes.  Numbered or coded bottles or containers.
  3. 3. Terms used in therapeutics  Blindness: any or all of the clinicians, patients, outcome assessors, or statisticians were unaware of who received which study intervention.  Contamination: occur when participants in either the experimental or control group receive the intervention for the other arm of the study.  Co-interventions: interventions other than treatment under study that are applied to the experimental or control groups .
  4. 4. Terms used in therapeutics  Intention to treat analysis: analyzing patient outcomes based on which group they were randomized regardless of whether they actually received the planned intervention.
  5. 5. EVIDENCE BASED MEDICINE
  6. 6. STATISTICS  Experimental event rate: The proportion of patients in the experimental treatment group who are observed to experience the outcome of interest.  Control event rate: The proportion of patients in the control treatment group who are observed to experience the outcome of interest.
  7. 7. STATISTICS    Absolute risk reduction/increase: Difference in the absolute risk in the exposed vs the unexposed. Relative risk: Ratio of the risk of an event among an exposed population to the risk among the unexposed. Relative risk reduction: An estimate of the proportion of baseline risk that is removed by the therapy.
  8. 8. STATISTICS  Number needed to treat: The number of patients who need to be treated over a specific period of time to prevent one adverse outcome.  Number needed to harm: The number of patients who need to be treated over a specific period of time to produce one adverse outcome.
  9. 9. THANK YOU
  10. 10. THANK YOU

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