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Reversing the Invisible Epidemic of Autoimmune Disease


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Now, more than ever before, is the time to address the autoimmune disease epidemic. With the convergence in science, tech, and patient demand, we can begin pieces the autoimmune puzzle together. With emerging tech, platforms and tools can improve care delivery. With your help, we can save millions.

Published in: Health & Medicine
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Reversing the Invisible Epidemic of Autoimmune Disease

  1. 1. © 2016 - All rights reserved. Reversing the Invisible Epidemic of Autoimmune Disease DIY Comes to Autoimmunity Your Autoimmunity Connection +1.310.666.5312 @DrBonnie360
  2. 2. © 2016 - All rights reserved. My Role: A=acking the Autoimmune Epidemic A huge, growing and untapped market opportunity > CVD + Cancer Obscured by staLsLcal gaps, scaMered across mulLple body parts and specialLes A big, expensive, underappreciated part of the chronic disease epidemic The @me is now to tackle this invisible epidemic! DrBonnie360’s Services •  Converging science, technology, paLent demand •  New R&D: -omics, immunology, systems biology, root-cause •  IT infrastructure: ubiquitous smart mobile, API/Cloud, WWW •  Emerging autoimmune communiLes, demand (e.g. diet) •  Emerging technology pla_orms •  Point soluLons in diabetes and obesity show how lifestyle modificaLons can improve quality of life and save money. •  New pla_orms, portals, communiLes are beginning to scale health, wellness and prevenLon. •  Advances in technology provide tools to improve care delivery Corporate Strategy Business Development Community Development CommunicaLons & Design MarkeLng & Sales
  3. 3. © 2016 - All rights reserved. Huge & Growing Unmet Need 50 Million (16%) Americans with Autoimmune Diseases •  1 in 6 Americans •  PopulaLon of 25 states •  > CVD + Cancer 100 + autoimmune diseases A Top 10 cause of death in women < 64 yo IBD incidence Doubled children < 10 yo (1991-2002 )
  4. 4. © 2016 - All rights reserved. Under-Recognized & Under-Researched: 16% 10% 6% 68% US Pa@ent Popula@on 6% 24% 37% 33% 2014 NIH Grant Alloca@ons Autoimmune Disease Cardiovascular Disease Cancer Other
  5. 5. © 2016 - All rights reserved. Untapped Market Opportuni@es By 2023, 230 Million Americans with chronic diseases, cosLng $4.2 Trillion total treatment plus economic output $8/10 spent on health care goes to chronic diseases 27% children <19 have at least one chronic condiLon 7/10 Deaths Annually due to chronic diseases 129% Increase for specialty autoimmune medicine from 2011-2015 ($20.9B – $47.9B)
  6. 6. © 2016 - All rights reserved. Opportunity for Individualized Autoimmune Medicine NOW Top-Down Convergence Advances in technology and science provide tools for digital individualized medicine: 2016 2015 2014 •  Apple, Amazon, Google enter healthcare market •  # of personal genomics companies doubled •  Cleveland Clinic opens a funcLonal medicine center •  Microbiome therapeuLcs •  Immuno-oncology •  Telemedicine & telehealth •  Virtual educaLon & digital coaching •  IBM Watson, Apple Healthkit •  AcLve M&A point soluLons to pla_orms •  Cleveland Clinic begins outcomes/cost clinical trials •  Wellness as a Service
  7. 7. © 2016 - All rights reserved. Need Individualized Autoimmune Medicine NOW BoMom-Up Convergence Autoimmune paLents desperately seeking earlier diagnoses and sustainable treatments that address root causes •  Gaps in diagnosis & treatment •  Average: 3.5 years & 5 doctors to Dx •  51% labeled chronic complainers •  More autoimmune than cancer paLents with poor quality of life •  Rheumatoid arthriLs 87% vs. Breast cancer 39% Needs Trends •  Crowdsourcing, CiLzen Science and maker movement •  Online community support groups & growing paLent power •  QuanLfied Self, N=1 Clinical Trials, experiments with diet & supplements •  Emergence of FuncLonal Medicine programs in convenLonal serngs
  8. 8. © 2016 - All rights reserved. -RemoteMonitoring - Chronic Disease Marketplace/Platform - Functional and Conventional Coordination -Personalization -Individualized -DataCollection REGENERATION Bridging the Gap – Individualized Autoimmune Care
  9. 9. © 2016 - All rights reserved. Contact Us +1.310.666.5312 @DrBonnie360 YourAutoimmunityConnecLon Bonnie Feldman, DDS, MBA DrBonnie360’s mission is to create a digitally connected world of personalized care for autoimmune paLents. We consult with start-up companies and entrepreneurs who are bringing new products and services that will improve research, diagnosis, and treatment for autoimmunity
  10. 10. © 2016 - All rights reserved. Sources •  Huge & Growing Unmet Need •  50 Million Americans & 100+ Autoimmune Disease – “Why is Auotoimmune Diseae Underserved,” DrBonnie360, Mar 2015. hMp:// •  Top 10 cause of death – AARDA Autoimmune Disease Fact Sheet. hMp:// autoimmune-staLsLcs/ •  Increasing Incidence in IBD – “Rising Incidence of Inflammatory Bowel Disease among Children: a 12-year Study,” Journal of Pediatric Gastroenterology & NutriLon, Jan 2010. hMp:// •  Under-recognized & Under-Researched •  16% of the US PopulaLon is Autoimmune – AARDA Autoimmune Disease Fact Sheet. hMp:// informaLon/autoimmune-staLsLcs/ •  <6% of NIH Funding goes to autoimmunity – “Health, United States, 2013 with Special Feature on PrescripLon Drugs,” Center for Disease Control and PrevenLon, 2014. hMp:// •  Untapped Market Opportunity •  27% of Children – “Chronic Care: Making the Case for Ongoing Care,” Robert Wood Johnson FoundaLon, Mar 2010. •  7/10 Deaths – “Chronic Disease PrevenLon and Health PromoLon,” Center for Disease Control and PrevenLon, Aug 2016. •  129% Increase – “Medicines Use and Spending in the U.S: A Review of 2015 and Outlook to 2020,” IMS InsLtute for Healthcare InformaLcs, Apr 2016. •  $8/10 Dollars – “The Digital RevoluLon comes to US Healthcare,” Goldman Sachs, Jun 2015. •  230M Americans cosLng $4.2T – “Checkup Time: Chronic Disease and Wellness in America,” Milken InsLtute, Jan 2014.