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CNS cell review questions.ppt

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CNS cell review questions.ppt

  1. 1. A cell which has abundant eosinophilic cytoplasm and is strongly positive for GFAP (glial fibrillary acidic protein) is most likely a (A) gemistocyte (B) microglial cell (C) oligodendroglial cell infected with JC virus (D) reactive ependymal cell (E) "red neuron"
  2. 2. A 17-year-old man strikes his head and becomes unconscious for 10 minutes following a automobile accident. A skull fracture is present. He recovers without any clinical residua. The blow resulted in a 2 mm area of superficial hemorrhage within his cerebral cortex. Which central nervous system cell is most likely to undergo hypertrophy and hyperplasia as a response to the injury? (A) astrocyte (B) ependymal (C) neuron (D) oligodendrocyte (E) Purkinje
  3. 3. Over a period of several years, a 70-year-old man develops progressive dementia. He dies of pneumonia. The accompanying photograph illustrates his brain as found at autopsy. Which of the following would be the abnormality expected in microscopic examination of his brain? (A) collection of lymphocytes in perivascular spaces (B) cortical neurofibrillary tangles (C) decreased pigmentation of the substantia nigra (D) glioblastoma multiforme of the cerebral cortex (E) stenosis of the aqueduct of Sylvius
  4. 4. In the central nervous system, myelin formation and maintenance is a function of (A) astrocytes (B) microglia (C) axons (D) oligodendroglia (E) neuron
  5. 5. In the brain, which of the following cells are most sensitive to anoxic damage? (A) astrocytes (B) oligodendroglia (C) microglia (D) neurons (E) ependyma

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