7. Statistical Analysis
Would it be enough to
collect N samples to reliably
detect the difference?
Correction for multiple testingHypothesis testing
p < 0.05
Amazing discovery by Estonian
Figure 1. Protoarray reactivities to type I interferons (IFNs) and to known autoantigens. The
reactivities to type I IFNs and known APECED autoantigens. The Protoarray signals are
expressed as z-scores representing the number of SDs from the mean of combined control
samples. Positive-negative discrimination level (dark red line) was set at z = 3. Red circles
represent the samples with z > 3, gray circles are control samples.