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Acupuncture for Patients
with Breast Cancer
Weidong Lu, MB, MPH, PhD
Oncology Acupuncturist
Zakim Center, Dana-Farber Cancer Institute
Harvard Medical School
Weidong_lu@dfci.harvard.edu
Oct. 5, 2013
What is Acupuncture?
• National Institutes of Health
Consensus Development Conference
Statement,1997:
• “Acupuncture describes a family of procedures
involving stimulation of anatomical locations on
the skin by a variety of techniques.”
• “The most studied mechanism of stimulation of
acupuncture points employs penetration of the
skin by thin, solid, metallic needles, which are
manipulated manually or by electrical stimulation.”
Top 10 Clinical Conditions being
Studied in Oncology Acupuncture Trials
21

Pain
10

Quality of Life

10

Fatigue
9

Nausea
8

Vomiting
7

Hot Flashes
5

Xerostomia
4

Joint Diseases
Arthralgia

4

Anxiety Disorders

4

0

5

10
Series1

15

20

Clinicaltrial.gov; Oct. 19, 2012

25
Clinical Trials of Oncology Acupuncture,
what we are studying? (based upon 73 studies)

Clinicaltrial.gov; Oct. 19, 2012
Pubmed Publications in Oncology Acupuncture: 19702012
Why Acupuncture?
• A high safety profile
• A non-pharmaceutical intervention
• Alleviates a wide variety of symptoms
simultaneously
• Supported by increasing scientific
evidence
Acupuncture Benefits for Patients with
Breast Cancer
•
•
•
•
•

Reduce cancer pain
Reduce nausea/vomiting
Improve sleep quality
Reduce hot flashes
Reduce fatigue
Acupuncture for Joint Pain in Breast
Cancer
• Randomized, Blinded, Sham-Controlled Trial
of Acupuncture for the Management of
Aromatase Inhibitor–Associated Joint
Symptoms in Women With Early-Stage
Breast Cancer

Crew, K. D. et al. J Clin Oncol; 28:1154-1160 2010
Acupuncture for Chemotherapy
Induced Nausea and Vomiting
• Electroacupuncture for Control of
Myeloablative Chemotherapy–Induced
Emesis A Randomized Controlled Trial
• To compare the effectiveness of electroacupuncture
vs minimal needling and mock electrical stimulation
or antiemetic medications alone in controlling emesis
among patients undergoing a highly emetogenic
chemotherapy regimen

• N=104, women with high-risk breast cancer
Shen, J. et al. JAMA 2000;284:2755-2761.
Acupuncture vs. venlafaxine for hot
flashes in breast cancer
Acupuncture versus venlafaxine for
the management of vasomotor
symptoms in patients with hormone
receptor-positive breast cancer: a
randomized controlled trial.
Walker, E. M. et al. J Clin Oncol; 28:634-640 2010
.
How to Access Zakim Center? A Phone Call Away!
Conclusions (1)
• Oncology acupuncture is an emerging
subspecialty in cancer care
• Oncology acupuncture distinctively
differs from traditional acupuncture
• Increasing evidence from clinical trials
supporting the use of acupuncture in
cancer care
Conclusions (2)
• Acupuncture is a safe intervention for patients
with breast cancer;
• Acupuncture is a reasonable option for
symptom management in patients with breast
cancer.
• Acupuncture benefits include reducing
pain, fatigue, insomnia, anxiety, and hot
flashes.
• More research is needed to incorporate
acupuncture into conventional breast cancer
treatment and survivorship.

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How Acupuncture Can Help Breast Cancer Patients

  • 1. Acupuncture for Patients with Breast Cancer Weidong Lu, MB, MPH, PhD Oncology Acupuncturist Zakim Center, Dana-Farber Cancer Institute Harvard Medical School Weidong_lu@dfci.harvard.edu Oct. 5, 2013
  • 2. What is Acupuncture? • National Institutes of Health Consensus Development Conference Statement,1997: • “Acupuncture describes a family of procedures involving stimulation of anatomical locations on the skin by a variety of techniques.” • “The most studied mechanism of stimulation of acupuncture points employs penetration of the skin by thin, solid, metallic needles, which are manipulated manually or by electrical stimulation.”
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  • 8. Top 10 Clinical Conditions being Studied in Oncology Acupuncture Trials 21 Pain 10 Quality of Life 10 Fatigue 9 Nausea 8 Vomiting 7 Hot Flashes 5 Xerostomia 4 Joint Diseases Arthralgia 4 Anxiety Disorders 4 0 5 10 Series1 15 20 Clinicaltrial.gov; Oct. 19, 2012 25
  • 9. Clinical Trials of Oncology Acupuncture, what we are studying? (based upon 73 studies) Clinicaltrial.gov; Oct. 19, 2012
  • 10. Pubmed Publications in Oncology Acupuncture: 19702012
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  • 12. Why Acupuncture? • A high safety profile • A non-pharmaceutical intervention • Alleviates a wide variety of symptoms simultaneously • Supported by increasing scientific evidence
  • 13. Acupuncture Benefits for Patients with Breast Cancer • • • • • Reduce cancer pain Reduce nausea/vomiting Improve sleep quality Reduce hot flashes Reduce fatigue
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  • 15. Acupuncture for Joint Pain in Breast Cancer • Randomized, Blinded, Sham-Controlled Trial of Acupuncture for the Management of Aromatase Inhibitor–Associated Joint Symptoms in Women With Early-Stage Breast Cancer Crew, K. D. et al. J Clin Oncol; 28:1154-1160 2010
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  • 19. Acupuncture for Chemotherapy Induced Nausea and Vomiting • Electroacupuncture for Control of Myeloablative Chemotherapy–Induced Emesis A Randomized Controlled Trial • To compare the effectiveness of electroacupuncture vs minimal needling and mock electrical stimulation or antiemetic medications alone in controlling emesis among patients undergoing a highly emetogenic chemotherapy regimen • N=104, women with high-risk breast cancer Shen, J. et al. JAMA 2000;284:2755-2761.
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  • 21. Acupuncture vs. venlafaxine for hot flashes in breast cancer Acupuncture versus venlafaxine for the management of vasomotor symptoms in patients with hormone receptor-positive breast cancer: a randomized controlled trial. Walker, E. M. et al. J Clin Oncol; 28:634-640 2010 .
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  • 31. How to Access Zakim Center? A Phone Call Away!
  • 32. Conclusions (1) • Oncology acupuncture is an emerging subspecialty in cancer care • Oncology acupuncture distinctively differs from traditional acupuncture • Increasing evidence from clinical trials supporting the use of acupuncture in cancer care
  • 33. Conclusions (2) • Acupuncture is a safe intervention for patients with breast cancer; • Acupuncture is a reasonable option for symptom management in patients with breast cancer. • Acupuncture benefits include reducing pain, fatigue, insomnia, anxiety, and hot flashes. • More research is needed to incorporate acupuncture into conventional breast cancer treatment and survivorship.

Editor's Notes

  1. Words “cancer” “stage” and “and” were removed from the list