Practical pathology revision 4th year 1st term 2013 miro

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Practical pathology revision 4th year 1st term 2013 miro

  1. 1. Revision
  2. 2. .Organ :- Intestine-Disease :- Para T.B- .Stain :- H & E-Lesion :- The intestinal mucosa is filled with-macrophages , giant cells and lymphocytes((granulomatous reaction
  3. 3. Paratuberculosis
  4. 4. paratuberculosisOrgan: intestineStain: Ziehl Neelsenlesion: the acid-fast bacilli is seen in the intestinal mucosa
  5. 5. Paratuberculosis
  6. 6. organ :- Endometrium--Stain :- H & E-Disease :- Brucellosis-Lesion :- severe endometritis represented bypreglandular round cell infiltration necroticendometeritis ch. By necrotic epi. + Adhesion .with few infl. Cell infiltration
  7. 7. Brucellosis
  8. 8. organ :- Endometrium--Stain :- H & E-Disease :- Brucellosis-Lesion :- severe endometritis represented bypreglandular round cell infiltration +Edema
  9. 9. Brucellosis
  10. 10. .Organ :- liver- .Stain :- H & E- .Disease :- Brucellosis-Lesion :- presence of pyogranuloma-characterized by presence of Caseous necrosissurrounded by epithelioid cells , giant cellsand neutrophils then enclosed by fibrous C.T
  11. 11. Brucellosis
  12. 12. .Organ :- liver- .Stain :- H & E- .Disease :- Brucellosis-Lesion :- presence of pyogranuloma-characterized by presence of Caseous necrosissurrounded by epithelioid cells , giant cellsand neutrophils then enclosed by fibrous C.T
  13. 13. Brucellosis
  14. 14. .Organ :- liver- .Stain :- H & E- .Disease :- Brucellosis-Lesion :- presence of pyogranuloma-characterized by presence of Caseous necrosissurrounded by epithelioid cells , giant cellsand neutrophils then enclosed by fibrous C.T
  15. 15. Brucellosis
  16. 16. .Organ :- Lung-Stain :- H & E-Disease :- T.B-Micro :- Granulomatous reaction + calcification- .in center
  17. 17. Tuberculosis
  18. 18. .Organ :- Lymph node-.Stain :- H & E-Disease :- T.B-Micro :- Granulomatous reaction + caseation &-.calcification
  19. 19. Tuberculosis
  20. 20. .Organ :- Kidney-Stain :- H & E-Disease :- T.B- .Micro :- Granulomatous reaction + Giant cells-
  21. 21. Tuberculosis
  22. 22. Tuberculosis
  23. 23. .Organ :- Lung- .Stain :- H & E- .Disease :- Pneumonic pasteurellosis-Lesion :- Fibrous bronchopneumonia-characterized by filling of alveoli withserofibrinous exudate infiltrated withneutrophils and macrophages , congestion of interalveolar capillaries and hemorrhage
  24. 24. Pasteurellosis
  25. 25. .Organ :- Lung- .Stain :- H & E- .Disease :- Pneumonic pasteurellosis-Lesion :- Fibrous bronchopneumonia-characterized by filling of alveoli withserofibrinous exudate infiltrated withneutrophils and macrophages , congestion of interalveolar capillaries and hemorrhage
  26. 26. Pasteurellosis
  27. 27. Pneumonic pasteurellosis.Organ :- Lung-.Stain :- Silver stain-.Disease :- Pneumonic pasteurellosis-Lesion :- Blackish stained P.hemorrage freely-inside alveolar lumen & trapped intra-alveolar.macrophage
  28. 28. Pasteurellosis
  29. 29. .Organ :- Lung- .Stain :- IHC- .Disease :- pneumonic pasteurellosis-Lesion :- Positive brown immunolabelling-against P.multocida mainly inside cytoplasm .of macrophages infiltrating lumen of alveoli
  30. 30. Pasteurellosis
  31. 31. Pasteurellosis
  32. 32. Organ :- Spinal cord-Stain :- H & E- ( Disease :- Actinomycosis ( A.pyogenes-Lesion :- Consists of centrally located bacterial-colonies surrounded by number of neutrophil,lymphocyte & epithelioid cells all surroundedby Fibrous C.T
  33. 33. Actinomyces pyogenes A. pyogenes
  34. 34. Actinomyces pyogenes
  35. 35. Organ :- Spinal cord-Stain :- H & E- ( Disease :- Actinomycosis ( A.pyogenes-Lesion :- Consists of centrally located bacterial-colonies surrounded by number of neutrophil,lymphocyte & epithelioid cells all surroundedby Fibrous C.T
  36. 36. Actinomyces pyogenes
  37. 37. Actinomyces pyogenes
  38. 38. Actinomyces pyogenes
  39. 39. Actinomyces pyogenes
  40. 40. Actinomyces pyogenes
  41. 41. Organ :- Intestine- (Stain :- IHC ( ImmunoHistoChemestry- Lesion :- Lowsenia enteritis-Micro :- Brown stained lowsenia enteritis in-lamina propria & in between intestine villi
  42. 42. Lawsonia intracellularis
  43. 43. Organ :- Intestine- (Stain :- IHC ( ImmunoHistoChemestry- Lesion :- Lowsenia enteritis-Micro :- Brown stained lowsenia enteritis in-lamina propria & in between intestine villi
  44. 44. Lawsonia intracellularis
  45. 45. .Organ :- Lung-.Disease :- Avian influenza-Micro :- Congestion, perivascular edema &-.fibrosis
  46. 46. Avian influenza -Lung
  47. 47. Avian influenza - Spleen
  48. 48. Avian influenzaOrgan: spleen Stain: H &E Disease: Avian influenzaLesion: hemorrhage , congestion & hemolysis of red pulp
  49. 49. Avian influenza ( High power of ( spleen
  50. 50. Avian influenzaOrgan: lung Stain: H &E Disease: Avian influenzaLesion: congestion, haemorrhage and hemosiderosis
  51. 51. Avian influenza
  52. 52. Organ :- Heart-Stain :- H & E-Disease :- Leukosis sarcoma-Micro :- Focal invasion & replacement of-myocardium with pleomorphic leukocytes
  53. 53. Avian leukosis
  54. 54. .Organ :- Intestine- .Stain :- H&E- .Disease :- Intestinal coccidiosis-Micro :- Various developmental stages of-coccidia were seen in the epithelial lining ofintestinal crypts (arrow) or free in lamina( .propria besides extravasated RBCs (arrow
  55. 55. Intestinal coccidiosis
  56. 56. Intestinal coccidiosis
  57. 57. Intestinal coccidiosis
  58. 58. .Organ :- Intestine- .Stain :- H & E- .Disease :- Ascariasis-Lesion :- Presence of adult worm in the lumen- .of intestine with desquamation of epithelium
  59. 59. Fowl Ascariasis
  60. 60. dermatophytosis• Organ: skin• Lesion:- dermatophytosis• Stain: H&E• Micro: severe inflammatory in skin beside loss of hair shaft and ectothrix
  61. 61. Dermatophtosis
  62. 62. Dermatophtosis – Hair follicle
  63. 63. .Organ :- Lung-.Stain :- PAS-.Disease :- Dermatophytosis-Micro :- PAS + hyphae are seen in skin-( .( Brownish color
  64. 64. .Organ :- Lung- .Stain :- H & E- .Disease :- Aspergillosis-Micro :- severe pneumonia appear as dense-rounded fosci eosinophilic center beside .granulomatous reaction
  65. 65. Aspergillosis
  66. 66. .Organ :- Intestine-Disease :- Para T.B- .Stain :- H & E-Lesion :- The intestinal mucosa is filled with-macrophages , giant cells and lymphocytes((granulomatous reaction
  67. 67. paratuberculosis - 9
  68. 68. Organ :- spleen-Stain :- H & E-Disease :- Brucellosis-Micro :- pyogranulomatous spleen represented-by aggregation of mononuclear cells,epithelioid cells & neutrophil
  69. 69. .Organ :- liver- .Stain :- H & E- .Disease :- Brucellosis-Lesion :- presence of pyogranuloma-characterized by presence of Caseous necrosissurrounded by epithelioid cells , giant cellsand neutrophils then enclosed by fibrous C.T
  70. 70. Brucellosis-17
  71. 71. Pneumonic pasteurellosis.Organ :- Lung-.Stain :- Silver stain-.Disease :- Pneumonic pasteurellosis-Lesion :- Blackish stained P.hemorrage freely-inside alveolar lumen & trapped intra-alveolar.macrophage
  72. 72. Pneumonic pasteurellosis silver stain
  73. 73. .Organ :- Lung- .Stain :- H & E- .Disease :- Pneumonic pasteurellosis-Lesion :- Fibrous bronchopneumonia-characterized by filling of alveoli withserofibrinous exudate infiltrated withneutrophils and macrophages , congestion of interalveolar capillaries and hemorrhage
  74. 74. Pneumonic pasteurellosis H & E-6
  75. 75. .Organ :- Lung- .Stain :- IHC- .Disease :- pneumonic pasteurellosis-Lesion :- Positive brown immunolabelling-against P.multocida mainly inside cytoplasm .of macrophages infiltrating lumen of alveoli
  76. 76. Pneumonic pasteurellosis IHC- 7
  77. 77. Pneumonic pasteurellosis IHC- 7
  78. 78. Organ :- Lung-Stain :- H & E-Disease :- Avian influenza-Micro :- Congestion & infiltration with-mononuclear cell in the interstitial tissue
  79. 79. Lung - Avian influenza
  80. 80. Organ :- Heart-Stain :- H & E-Disease :- Leukosis sarcoma-Micro :- Focal invasion & replacement of-myocardium with pleomorphic leukocytes
  81. 81. Heart - Leukosis sarcoma
  82. 82. Organ :- Spleen-Stain :- H & E-Disease :- Avian influenza-Micro :- Periarteriolar edema & necrosis of- lymphoid tissue
  83. 83. Spleen - Avian influenza
  84. 84. Organ :- Spinal cord-Stain :- H & E- ( Disease :- Actinomycosis ( A.pyogenes-Lesion :- Consists of centrally located bacterial-colonies surrounded by number of neutrophil,lymphocyte & epithelioid cells all surroundedby Fibrous C.T
  85. 85. (Actinomycosis ( A.pyogenes
  86. 86. (Actinomycosis ( A.pyogenes
  87. 87. Organ :- Intestine- (Stain :- IHC ( ImmunoHistoChemestry- Lesion :- Lowsenia enteritis-Micro :- Brown stained lowsenia enteritis in-lamina propria & in between intestine villi
  88. 88. Lowsenia enteritis
  89. 89. .Organ :- Intestine- .Stain :- H & E- .Disease :- Ascariasis-Lesion :- Presence of adult worm in the lumen- .of intestine with desquamation of epithelium
  90. 90. .Organ :- Intestine- .Stain :- H&E- .Disease :- Intestinal coccidiosis-Micro :- Various developmental stages of-coccidia were seen in the epithelial lining ofintestinal crypts (arrow) or free in lamina( .propria besides extravasated RBCs (arrow
  91. 91. .Organ :- Skin- .Stain :- H&E- .Disease :- Fowl pox-Micro :- The skin showed hyperplasia of prickle-cell layer which contain ICIB moreover theprickle cell layer shows hydropic degeneration.
  92. 92. .Organ :- Lung-.Stain :- PAS-.Disease :- Dermatophytosis-Micro :- PAS + hyphae are seen in skin-( .( Brownish color
  93. 93. .Organ :- Skin- .Stain :- H & E- .Disease :- Dermatophytosis-Micro :- Severe inflammatory reaction-(dermatitis) in the skin besides loss of hairshaft, the presence of perifollicular ectothrix, . arthrospores & hyperkeratosis
  94. 94. .Organ :- Lung- .Stain :- H & E- .Disease :- Aspergillosis-Micro :- severe pneumonia appear as dense-rounded fosci eosinophilic center beside .granulomatous reaction

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