Prevention of Heart attack, Stroke, Myocardial infarction.Our method


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Cardiovascularprevention.con is a website for prevention of cardiovascular disease. Heart attack, sudden death or stroke is the first sign of cardiovascular disease in one third of healthy people. In this slide presentation you can find our innovative methods for assesing the first sign of atherosclerosis and the managment of cardiovascular risk in healty individuals...and more.

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Prevention of Heart attack, Stroke, Myocardial infarction.Our method

  1. 1. Searching for Vulnerable Subject g j Best results for the Patient • Actual Model(symptoms) ( y p ) 43% Survival CVD’s Risk Factors, Drugs, CABG, Devices… • Long Term Model g 85% Survival Genetic Panel Significant impact on Select and monitor p productivity and Costs y Population at risk saving. Treat specific Patients 2
  2. 2. Who is the Vulnerable Subject ? j He is an High risk person: - Asymptomatic - h i subclinical atherosclerosis having b li i l h l i not detectable by common risk factor assessment He needs aggressive treatment , but he do not know it - Almost all vulnerable individuals have detectable subclinical atherosclerosis - New technology can identify vulnerable individuals with sufficient predictive power ffi i t di ti
  3. 3. Cholesterol Failed Quantification of Cholesterol and common Risk Factors failed to predict more than 1/3 of future cardiac death rising from Ischemic heart disease LDL Goal Patient Cholesterol LDL goals are 2001* 2004† progressively lowered for High-risk < 100 < 70 CVD prevention, in agree to Moderate-risk < 130 < 100 NCEP panel III Low-risk < 160 < 160 NCEP ATP III = National Cholesterol Education Program Adult Treatment Panel III; LDL = low-density 4 lipoprotein: Charles H. Hennekens, MD; Medscape General Medicine. 2006;8(1):54.
  4. 4. Carotid Intima Media Thickness (CIMT) Intima-Media 5
  5. 5. CALCIUM SCORE • I the normal artery calcification are not present. In th l t l ifi ti t t • The presence of coronary calcification indicates the existence of coronary disease disease. • The amount of calcification was correlated with the amount of plaque and the number of coronary stenoses. • The research of coronary calcium is an excellent y method of screening asymptomatic patients. • The positive predictive power varies from 20 to 35% and negative predictive power i close t d ti di ti is l to 100%. 6
  6. 6. CALCIUM SCORE ASSOCIATED WITH OTHER RISK FACTORS (From: Raggi e coll. Am. Heart J. March 2001). 7
  7. 7. SURVIVAL IN RELATION TO CALCIUM SCORE Survival in 4474 males 3219 females with more than one risk factor in relation to the values of calcium scores measured by EBCT (Bethesda conference, Jacc 41, 11 2003) 8
  8. 8. Coronary TC Angiography and Calcium score 9
  9. 9. Coronary TC Angiography 3D rendering 10
  10. 10. Coronary TC Angiography Little calcified plaque(arrows) 11
  11. 11. Coronary TC Angiography Proximal LAD Small calcified plaque (arrows) particular 12
  12. 12. Coronary TC Angiography Cx Artery and collateral RA and IVP artery branch 13
  13. 13. Right Artery and small septal vessels(arrows) g y p ( ) Coronary TC Angiography Traditional Coronary Angiography 14
  14. 14. Searching for Vulnerable Subject CV Risk Personal ranking Very High Risk: >20% High: >2% High :6<20% g Intermediate : 0.6-5,9 % Low: <0 5 % L <0.5 15
  15. 15. 16
  16. 16. Noninvasive Screening for Coronary Artery Disease With Computed Tomography Is Useful Melvin E. Clouse, MD , 17
  17. 17. Our Program: Discover the Vulnerable Subject Our Method Actual Method § Clinical history y Risk Factors § Common Risk evaluation in Factors study agreement of § New CVD's Markers Framingham model F i h d l and §CIMT NCEP Panel III = § Calcium Score Index Insufficient 50% § Coronary CT angiography (if indicated) 18
  18. 18. www CardioVascularPrevention com E-mail: 23