COMPARISON OF
HYDROPHOBIC CHARACTERISTICS
FROM DIFFERENT WOUND DRESSINGS
Braunwarth H1 and Brill FHH2
1Coloplast GmbH , Ha...
Two antimicrobial concepts
for treatment of bacterial burden
in chronic wounds:
1st Release of antimicrobial substances in...
Wound dressings coated with DACC1 claim a hydrophobic
characteristic for irreversible binding of bacteria to the dressing....
METHODS II/III
 A drop of artificial wound liquid1 was placed on the surface of
the wound dressing and a picture with a C...
METHODS III/III
- Test dressings -
5
Dressing Manufacturer Category Lot.
Acticoat Moisture Control Smith&Nephew GmbH Polyu...
6
RESULTS I/III
- Contact angle in degree by product -
Dressing Manufacturer Category Average SD Median SD
Acticoat Moistu...
0,0
20,0
40,0
60,0
80,0
100,0
120,0
140,0Contactangleindegree
7
/1/ Cutimed Siltec Sorbact, BSN medical GmbH, /2/ Cutimed ...
8
8
Category Average SD Median SD
Acetate gauze coated with DACC /1/ 100,6 12,64 106,0 12,64
DACC-impregnated cotton gauze...
9
1st 32 wound dressings were tested. 29 wound dressings (91%) showed contact
angles >80 degrees and 22 showed contact ang...
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EWMA 2013 - Ep481 - COMPARISON OF HYDROPHOBIC CHARACTERISTICS FROM DIFFERENT WOUND DRESSINGS

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Braunwarth H1 and Brill FHH2 1Coloplast GmbH , Hamburg, Germany 2Dr. Brill + Partner GmbH, Institute for Hygiene and Microbiology , Hamburg, Germany

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EWMA 2013 - Ep481 - COMPARISON OF HYDROPHOBIC CHARACTERISTICS FROM DIFFERENT WOUND DRESSINGS

  1. 1. COMPARISON OF HYDROPHOBIC CHARACTERISTICS FROM DIFFERENT WOUND DRESSINGS Braunwarth H1 and Brill FHH2 1Coloplast GmbH , Hamburg, Germany 2Dr. Brill + Partner GmbH, Institute for Hygiene and Microbiology , Hamburg, Germany EP 481 EWMA Congress 2013, Copenhagen 1
  2. 2. Two antimicrobial concepts for treatment of bacterial burden in chronic wounds: 1st Release of antimicrobial substances into the wound and killing the bacteria in the wound and in the wound dressing 2nd Removing the bacteria from the wound by physical methods 2 INTRODUCTION
  3. 3. Wound dressings coated with DACC1 claim a hydrophobic characteristic for irreversible binding of bacteria to the dressing. The aim of this in-vitro-study was to compare the hydrophobic characteristics of these with other wound dressings. 3 1DACC= Dialkylcarbamoylchlorid, Cutimed Sorbact, BSN medical GmbH AIM
  4. 4. METHODS II/III  A drop of artificial wound liquid1 was placed on the surface of the wound dressing and a picture with a Canon EOS 400D (18-55 mm) was taken immediately and the contact angle was measured from a print of the picture.  The measurement were repeated 5-10 times and the arithmetic average and standard deviation was calculated. 41Reitzel et al. An in-vitro test of absorption capacity of foam dressings under pressure. Posters, EWMA 2008 and WUWHS 2008 Wound dressing Biatain Soft-Hold Artificial wound exsudate
  5. 5. METHODS III/III - Test dressings - 5 Dressing Manufacturer Category Lot. Acticoat Moisture Control Smith&Nephew GmbH Polyurethane foam dressing with Ag 1230 Allevyn Silver Non-Adhesive/ Allevyn Silver Adhesive Smith&Nephew GmbH Polyurethane Foam dressing with Ag 1138 1303 Allevyn Ag Gentle/ Allevyn Ag Gentle Border Smith&Nephew GmbH Foam dressing with Ag and coated with soft-gel 1242 1242 AMD Antimicrobial Foam Dressing Covidien Deutschland GmbH Foam dressing with PHMB 909150 Atrauman Ag Paul Hartmann AG Impregnated gauze 200527116 Biatain Non-Adhesive/ Biatain Adhesive Coloplast GmbH Polyurethane foam dressing 345502 3431148 Biatain Soft-Hold Coloplast GmbH Polyurethane foam dressing 3208974 Biatain Ag Adhesive Biatain Non-Adhesive Coloplast GmbH Polyurethane foam dressing with Ag 2965322 3585488 Biatain Silicone Ag Coloplast GmbH Polyurethane foam dressing with Ag WO006285 Biatain Silicone/ Biatain Silicone Light1 Coloplast GmbH Foam dressing coated with silicone 3620749 Cutimed Siltec Sorbact BSN medical GmbH Foam dressing/Acetate gauze coated with DACC 24060741 Cutimed Siltec BSN medical GmbH Foam dressing/Acetate gauze with super absorber 24820741 Cutimed Sorbact Round swab BSN medical GmbH Acetate gauze coated with DACC 243093 Cutimed Sorbact Ribbon gauze BSN medical GmbH Impregnated cotton gauze 239093 Cutimed Sorbact Dressing pad BSN medical GmbH Acetate gauze coated with DACC, polyester and viskose 223093 Cutimed Sorbact Hydroactive Gel dressing BSN medical GmbH Acetate gauze coated with DACC and Gel 243469 Cutimed Sorbact Hydroactive B Gel dressing with border BSN medical GmbH Acetate gauze coated with DACC and Gel 227469 Cutimed Siltec L Thin super-absorbent silicone foam dressing BSN medical GmbH Foam dressing coated with silicone 3560741 DracoFoam PHMB Dr. Ausbüttel & Co. GmbH Foam dressing with PHMB 11050443 Mepilex Border/ Mepilex Border Lite Mölnlycke Health Care GmbH Foam dressing coated with silicone 10115530 11180960 Mepilex Ag/ Mepilex Ag Border Mölnlycke Health Care GmbH Foam dressing with Ag and coated with silicone 12446376 12446376 Urgotül AG Lite Border Urgo GmbH Impregnated (hydrocolloid particles and petrolatum) polyester gauze and Ag 36533 Urgocell AG Silver Border Urgo GmbH Foam dressing with Lipidokolloid-Matrix (TLC) and Ag 34425 Urgotul Silver AG Plata/ Urgotul Silver Plata NA Urgo GmbH Lipido-colloid contact layer with Ag 32393 24424 1 Test production
  6. 6. 6 RESULTS I/III - Contact angle in degree by product - Dressing Manufacturer Category Average SD Median SD Acticoat Moisture Control Smith&Nephew GmbH Polyurethane foam dressing 105,2 9,23 109 9,23 Allevyn Silver Non-Adhesive Smith&Nephew GmbH Polyurethane foam dressing with Ag 100,7 7,09 100 7,09 Allevyn Silver Foam Dressing Adhesive Smith&Nephew GmbH Polyurethane foam dressing with Ag 94,8 1,71 94,5 1,71 Allevyn Ag Gentle Smith&Nephew GmbH Foam dressing with Ag and coated with silicone 92,9 3,28 94 3,28 Allevyn Ag Gentle Border Smith&Nephew GmbH Foam dressing with Ag and coated with silicone 99,4 10,7 96 10,7 AMD Antimicrobial Foam Dressing Covidien Deutschland GmbH Foam dressing with PHMB 80,7 3,08 81,5 3,08 Atrauman Ag Paul Hartmann AG Impregnated gauze 71,2 6,62 72 6,62 Biatain Non-Adhesive Coloplast GmbH Polyurethane foam dressing 85,3 8,22 86 8,22 Biatain Soft-Hold Coloplast GmbH Polyurethane foam dressing 91,5 3,1 92 3,1 Biatain Adhesive Coloplast GmbH Polyurethane foam dressing 88,3 4,68 87 4,68 Biatain Ag Non-Adhesive Coloplast GmbH Polyurethane foam dressing with silver 77,1 4,27 76,5 4,27 Biatain Ag Adhesive Coloplast GmbH Polyurethane foam dressing with silver 85,9 4,04 85,5 4,04 Biatain Silicone Ag Coloplast GmbH Polyurethane foam dressing 83,8 6,91 84,5 6,91 Biatain Silicone Coloplast GmbH Polyuretane foam dressing coated with silicone 95,9 9,33 94 9,33 Biatain Silicone Lite Coloplast GmbH Polyuretane foam dressing coated with silicone 95,3 5,68 97 5,68 Cutimed Siltec Sorbact BSN medical GmbH Acetate gauze coated with DACC 100,6 12,64 106 12,64 Cutimed Siltec BSN medical GmbH Foam dressing with super absorber 91,8 8,52 90,5 8,52 Cutimed Sorbact Round swab BSN medical GmbH Acetate gauze coated with DACC 82 24,27 69 24,27 Cutimed Sorbact Ribbon gauze BSN medical GmbH Impregnated cotton gauze 120,3 7,91 120 7,91 Cutimed Sorbact Dressing pad BSN medical GmbH Acetate gauze coated with DACC, polyester and viscose 90,9 2,23 90 2,23 Cutimed Sorbact Hydroactive Gel dressing BSN medical GmbH Acetate gauze coated with DACC and Gel 107,1 10,29 105 10,29 Cutimed Sorbact Hydroactive B Gel dressing with border BSN medical GmbH Acetate gauze coated with DACC and Gel 114,9 8,84 116 8,84 Cutimed Siltec L Silicone Foam dressing BSN medical GmbH Foam dressing coated with silicone 96,9 3,54 97 3,54 DracoFoam PHMB Dr. Ausbüttel & Co. GmbH Foam dressing with PHMB 77,9 8,15 79 8,15 Mepilex Border Mölnlycke Health Care GmbH Foam dressing coated with silicone 105,8 7,27 104,5 7,27 MepilexBorder Lite Mölnlycke Health Care GmbH Foam dressing coated with silicone 100,3 12,47 101,5 12,47 Mepilex Border Ag Mölnlycke Health Care GmbH Foam dressing with Ag and coated with silicone 100,2 7,56 98 7,56 Mepilex Ag Mölnlycke Health Care GmbH Foam dressing with Ag and coated with silicone 115,7 11,76 116 11,76 Urgotül AG Lite Border Urgo GmbH Impregnated polyester gauze and Ag 75,3 2,5 75,5 2,5 Urgocell AG Silver Border Urgo GmbH Foam dressing with Lipido-colloid-Matrix (TLC) 94,3 5,09 95 5,09 Urgotul Silver AG Plata Urgo GmbH Lipido-colloid contact layer 101,5 6,66 103 6,66 Urgotul Silver AG Plata NA Urgo GmbH Lipido-colloid contact layer 96,4 5,89 95,5 5,89
  7. 7. 0,0 20,0 40,0 60,0 80,0 100,0 120,0 140,0Contactangleindegree 7 /1/ Cutimed Siltec Sorbact, BSN medical GmbH, /2/ Cutimed Sorbact Ribbon gauze, BSN medical GmbH , /3/ Cutimed Sorbact Dressing pad, BSN medical GmbH, /4/ Cutimed Sorbact Hydroactive B Gel dressing with border, /5/ Urgotül Ag Lite Border, Urgo GmbH, /6/ Atrauman Ag, Paul Hartmann AG, /7/ Urgotul Silver Ag Plata/Plata NA, Urgo GmbH, /8/ Biatain Non-Adhesive/Adhesive, Coloplast GmbH, /9/ Cutimed Siltec, BSN medical GmbH, /10/ Biatain Soft-Hold, Coloplast GmbH , /11/ Urgocell Ag Silver Border, Urgo GmbH, /12/ Allevyn Silver Non-Adhesive/Adhesive, Smith&Nephew GmbH, /13/ Acticoat Moisture Control, Smith&Nephew GmbH, /14/ Biatain Ag Non-Adhesive/Adhesive, Coloplast GmbH, /15/ DracoFoam PHMB, Ausbüttel&Co GmbH, /16/ AMD Antimicrobial Foam Dressing, Covidien Deutschland GmbH, /17/ Mepilex Border/Border Lite, Mölnlycke Healthcare GmbH, /18/ Mepilex Ag/Border Ag, Mölnlycke Healthcare GmbH, /19/ Biatain Silicone/Silicone Light, Coloplast GmbH, /20/Allevyn Ag Gentle/Gentle Border, Smith&Nephew GmbH RESULTS II/III - Average and Standard Deviation Contact Angle in degree by category - 80o 90o
  8. 8. 8 8 Category Average SD Median SD Acetate gauze coated with DACC /1/ 100,6 12,64 106,0 12,64 DACC-impregnated cotton gauze /2/ 120,3 7,91 120,0 7,91 Acetate gauze coated with DACC, polyester and viscose /3/ 90,9 2,23 90,0 2,23 Acetate gauze coated with DACC and gel /4/ 107,1 10,29 105,0 10,29 Impregnated gauze with Ag /5/ 75,3 2,50 75,5 2,50 Impregnated gauze /6/ 71,2 6,62 72,0 6,62 Lipid-Colloid Contact Layer /7/ 98,5 6,69 98,0 6,69 Polyurethan-Foam Dressing /8/ 85,9 7,70 87,0 7,70 Foam dressing with super absorber /9/ 91,8 8,52 90,5 8,52 Polyurethane foam dressing coated with adhesive /10/ 91,5 3,10 92,0 3,10 Foam dressing with Lipidokolloid-Matrix (TLC) /11/ 94,3 5,09 95,0 5,09 Polyurethane foam dressing with Ag /12/ 99,9 6,89 100,0 6,89 Polyurethane foam dressing with Ag /13/ 105,2 9,23 109,0 9,23 Polyurethane foam dressing with Ag /14/ 83,8 6,91 84,5 6,91 Foam dressing with PHMB /15/ 77,9 8,15 79,0 8,15 Foam dressing with PHMB /16/ 80,7 3,08 81,5 3,08 Foam dressing coated with silicone /17/ 102,5 10,58 102,0 10,58 Foam dressing coated with silicone and Ag /18/ 110,5 12,74 112,0 12,74 Polyurethane foam dressing coated with silicone /19/ 95,8 8,76 97,0 8,76 Foam dressing coated with soft gel and Ag /20/ 96,2 8,39 94,0 8,39 Contact angle > 90 degree RESULTS I/III - Contact angle in degree by category - /1/ Cutimed Siltec Sorbact, BSN medical GmbH, /2/ Cutimed Sorbact ribbon gauze, BSN medical GmbH , /3/ Cutimed Sorbact dressing pad, BSN medical GmbH, /4/ Cutimed Sorbact Hydroactive B gel dressing with border, /5/ Urgotül Ag Lite Border, Urgo GmbH, /6/ Atrauman Ag, Paul Hartmann AG, /7/ Urgotul Silver Ag Plata/Plata NA, Urgo GmbH, /8/ Biatain Non-Adhesive/Adhesive, Coloplast GmbH, /9/ Cutimed Siltec, BSN medical GmbH, /10/ Biatain Soft-Hold, Coloplast GmbH , /11/ Urgocell Ag Silver Border, Urgo GmbH, /12/ Allevyn Silver Non-Adhesive/Adhesive, Smith&Nephew GmbH, /13/ Acticoat Moisture Control, Smith&Nephew GmbH, /14/ Biatain Ag Non-Adhesive/Adhesive, Coloplast GmbH, /15/ DracoFoam PHMB, Ausbüttel&Co GmbH, /16/ AMD Antimicrobial Foam Dressing, Covidien Deutschland GmbH, /17/ Mepilex Border/Border Lite, Mölnlycke Healthcare GmbH, /18/ Mepilex Ag/Border Ag, Mölnlycke Healthcare GmbH, /19/ Biatain Silicone/Silicone Light, Coloplast GmbH, /20/Allevyn Ag Gentle/Gentle Border, Smith&Nephew GmbH
  9. 9. 9 1st 32 wound dressings were tested. 29 wound dressings (91%) showed contact angles >80 degrees and 22 showed contact angles >90 degrees (69%). 2nd Cutimed Sorbact showed the greatest contact angle (120 degrees) and Atrauman the smallest contact angle (71%). 3rd DACC coated wound dressings, foam wound dressings with or without active substances, wound dressings fully or partly coated with silicone showed contact angles >90 degrees and could therefore classified as hydrophobic. 4th The hydrophobic effect is not a specific feature of DACC-coated products. All tested foam dressings, coated with silicone or uncoated, showed a hydrophobic effect. SUMMARY AND CONCLUSION

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