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Effec%veness	  Of	  Individualized	  Non-­‐Supervised	  Coached	  Exercise	  Program	  	                                   ...
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Helping Children with Cystic Fibrosis: Testing the Effectiveness of Individualized Non-Supervised Coached Exercise Program

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A poster presentation by UCSF researcher Mona Luke-Zeitoun and colleagues from Stanford University and University of Pittsburgh.

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Helping Children with Cystic Fibrosis: Testing the Effectiveness of Individualized Non-Supervised Coached Exercise Program

  1. 1. Effec%veness  Of  Individualized  Non-­‐Supervised  Coached  Exercise  Program     In  Children  With  Cys%c  Fibrosis     M  Luke-­‐Zeitoun1,  D  Nielson1,  D  Orenstein3,  J  Desch2,  R  Moss2   University  of  California  San  Francisco1,  Stanford  University2,  University  of  PiPsburgh3   Background   Methods   Results  • The  benefits  of  exercise  in  CF  pa<ents  are  well   • Assessments  included:  maximal  oxygen  uptake  tes<ng  established  (improved  survival,  slower  decline  in   (VO2max),  strength  tes<ng,  ease  of  breathing  pulmonary  func<on,  enhanced  sputum  clearance)   measurements,  skin  fold  measurements  • Supervised,  standardized  exercise  programs  effec<vely   • A  licensed  personal  trainer  coached  the  children  in  the  improve  clinical  status  in  CF  but  show  poor  long-­‐term   exercise  group  to  design  an  individualized  exercise  adherence   program  that  included  weekly  video  conference  sessions  • Individualized  programs,  incorpora<ng  enjoyed  ac<vi<es,   to  assist  in  their  goals,  monitor  progress  and  modify  the  regular  therapist-­‐pa<ent  contact  and  family  support  are   program  as  needed  associated  with  good  long-­‐term  adherence   Objec%ves  • To  examine  the  effects  of  an  individualized  unsupervised   • Exercise  group  showed  over  6  months:  coached  exercise  program  in  children  with  CF  on  lung   • Stabiliza<on  of  lung  func<on    func<on,  aerobic  capacity,  muscle  strength,  ease  of   • Improvement  in  arm/shoulder  strength  (push  ups)  breathing,  long  term  adherence   • Trend  to  improvement  in  leg  and  abdominal  muscle   strength  (wall  sit,  sit  ups)   Methods   Results   • Control  group  showed  over  6  months:   • Decline  in  lung  func<on  • Design   • Trend  to  decline  in  leg  and  abdominal  muscle   • Randomized  controlled  study   strength  • Par<cipants   • Trend  to  improvement  in  arm/shoulder  strength   • 11  children  with  CF  between  9  and  15  years  (6  girls)   • Ease  of  breathing  measurements  remained  unchanged   • 7  pa<ents  in  exercise  group,  4  in  control  group   in  both  groups  • Exercise  group  par<cipated  in  a  6-­‐month  individualized  non-­‐ • 12  month  measurements  are  expected  to  be  supervised  training  exercise  program   completed  in  all  subjects  by  the  end  of  2012  • Control  group  was  asked  not  to  alter  their  ac<vity  levels  • Pa<ents  were  assessed  at  baseline,  a[er  6  months,  and  a[er  12  months   • No  difference  in  baseline  characteris<cs  between   Conclusions   exercise  and  control  group  Testing Testing Testing • Age   • Individualized  non-­‐supervised  coached  exercise   • Lung  func<on  (FEV1)   programs  may  be  effec<ve  in  stabilizing  lung  func<on   • Maximal  oxygen  uptake  (VO2max)   and  improving  physical  fitness  in  children  with  CF  and   0 6 12 mo mo mo • Body  composi<on  (percentage  body  fat)   could  poten<ally  be  used  as  a  method  to  improve  the   Exercise overall  health  and  well-­‐being  of  these  children   Program FUNDING:  NIH/NCRR  UCSF-­‐CTSI  Grant  Number  UL1  RR024131   This project was supported by the CTSI- Clinical Research Services -Body Composition/Exercise Core. For more info visit http://accelerate.ucsf.edu/research/crs

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