• Pfizer: Paxlovid
– Strongly effective in preventing severe
COVID when given to high-risk
unvaccinated patients soon after they
started showing symptoms
• Merck: Molnupiravir (Lagevrio)
– Inhibits virus replication
• Paxlovid (PF-07321332 + ritonavir)
– SARS-CoV-2 protease inhibitor
– Take at first sign of infection or
awareness of an exposure
– Help avoid severe illness
– 89 percent if started within 3 days of
• Fourth or fifth day, the pill reduced the risk
of hospitalization or death by 85 percent
• Lagevrio (Molnupiravir)
– Nucleoside derivative N4-hydroxycytidine –
introduces copying errors during viral RNA
• Incorporates NHC-TP into newly made
RNA instead of using real cytidine (C)
• About 50 percent effective when given
within five days of the onset of
COVID-19 Vaccinations across the Nation
COVID-19 Boosters Across the Nation
Percent Fully Vaccinated by State for the Total Population
Researching Communities Ahead
Are there gaps in community-based
service organizations in the area or
communication with them?
(Make connections with them ahead)
Are there gaps in healthcare or other
services in the community being
served? Labs, specialists, etc.
(Can we make connections ahead?)
Are there gaps in resources that can be
referred to in the community being
served? Food, housing, etc.
(Can you develop a community resource
list ahead of the outreach?)
Are there other gaps like supplies,
household items, etc. that can be
brought to outreach events?
(Prepare list and bring items if possible)
Remember to ask questions and provide information in a culturally
• Intimate Partner Violence
• Housing/Food Insecurity
• Lack of Insurance
• Lack of US legal Status
• Justice Involved
• Migrant/Seasonal Farm
• Substance Users
Use Existing Resources
• Request participation in established
• Request increased communication with
housing case managers, soup kitchen outreach
• Join Community Care Team meetings
• Actively participate in committees, consortia,
and networks that work with your target
What is Different with the Booster?
• The messaging is less urgent
– especially in CT
• It is harder to determine
who needs them – are you
• Competing priority of getting
kids vaccinated versus
• Convenience – mass vax
sites are closed
Messaging for 5-12 Year Old Families
• You control the tone of the conversations – be
upbeat, positive and calm.
• It may take several conversations to engage adults in
• Consistency is important in setting the tone for child
• Use Culturally relevant/humble information.
• Location is important.
Outreach to 5-12 Year old Families
• Interchange COVID-19 and Coronavirus
• Who are your adults?
• Can I speak to the adults who care for you at home?
• Vaccines are a type of medicine that prevent certain
kinds of sickness.
• May I give you some information about…….
What parents are telling us:
• If the shot is available when we tell them about it, then they
are more likely to get it for their child.
• Having to come back many times for their own shot was a
deterrent for parents to get child vaccinated.
• Feel child is protected if the adults in family are vaccinated.
• Perception that kids are less likely to be affected by COVID-19.
• Some parents were uncomfortable having it done in school
because they wanted to be present.
Successful Locations for Families
• Schools and School Based
• Civic Organizations
• Grocery Stores
• Barber Shops/Hair Salons
• YMCA and YMCA Afterschool
• Food Pantries/Food
• Community Events/Fairs
• Public Housing
• Key Partners: Schooling and Nursing staff
• Parental consent
• Saturday clinics for younger children
Partnerships with Municipalities
• Equity in access to vaccine
• Addressing questions about vaccine
• Using social media as a tool for communication and
• Neighborhood leaders in faith-based communities
Partnerships with Small Businesses
• Small businesses as trusted messengers
• McDonald’s franchise partnership
Intro: Here you can see from the map the ‘hot spots’ occurring around the country. The Darker colors mean more active infections
11/15: national case average has been relatively flat in recent weeks, but worsening in parts of the West, Upper Midwest and Northeast The average number of new cases increased more than 40 percent over a two-week period in New Mexico, Colorado, Illinois and Minnesota. Vaccination rates in those states are a bit above the national average, and the outlook is not yet nearly as dire as what Southern states saw this summer.
Conditions continue to improve in the South. Florida and Louisiana, which had two of the worst summer surges, have new cases at some of the lowest rates in the US
11/15: There are fewer than half as many coronavirus patients in American hospitals as there were in early September.
Seventy percent of American adults, and 59 percent of all Americans, are fully vaccinated. About 1.3 million doses are being administered each day, a number that grew rapidly after booster doses and vaccines for younger children were authorized.
Molnupiravir: nucleoside derivative N4-hydroxycytidine (also called EIDD-1931), and exerts its antiviral action through introduction of copying errors during viral RNA replication incorporates NHC-TP into newly made RNA instead of using real cytidine
ritonavir helps slow the metabolism, or breakdown, of PF-07321332 in order for it to remain active in the body for longer periods of time at higher concentrations
Phase 2/3 EPIC-PEP (Evaluation of Protease Inhibition for COVID-19 in Post-Exposure Prophylaxis) to evaluate efficacy and safety in adults exposed to SARS-CoV-2 by a household member.
11/2: Connecticut now 70.8 up from 69.9% 2 weeks ago Vermont: now 71.3 up from 70.6% Puerto Rico – doing very well: 73.6 up from 72% immunized Alaska – 52.7 up from 51.7%