1. Historical Recall of the
Nature Saga
Bernard Sudan, France and Switzerland

2. The Human Basophil Degranulation Test (HBDT) of
Benveniste was used to demonstrate a biological
activity at high dilutions in « Nature, June 30, 1988 »

3. The Human Basophil Degranulation
Test (HBDT) of Benveniste was
widely used for diagnostic purposes
over the world in allergology since
1978 !
(in Encyclopedia Britannica)
“Benveniste’s work was his hypothesis (first
published in the journal Nature in 1988) that when
dissolved in water, a substance acts like a template,
altering the electromagnetic properties of the water.
In subsequent dilutions these properties would be
transferred to newly added water; the water would
thus retain a “memory” of the substance dissolved in
the initial solution”

4. Editorial reservation in Nature 1988: an unfair method to
discreditate the research of Jacques Benveniste !
« There is no physical basis for such an activity » …John Maddox
Unique in the history of research publications !

5. « I assume that you used the standard version of Benveniste’s
test in your work, the value of which is not disputed » !

6. « I assume that you used the standard version of
Benveniste’s test in your work, the value of which is
not disputed » ! = a non sense and fatal mistake !
Jacques Benveniste et l'erreur fatale de
John Maddox, éditeur de Nature...
•20 DÉC. 2013 PAR BERNARD SUDAN BLOG : LE BLOG DE BERNARD SUDAN

7. The causes of editorial reservation and
discreditation…for research on high dilutions of
Jacques Benveniste 192 years after first observations
of Samuel Hahnemann…:
• Digital biology as a new treatment at a low cost and without
side-effects = THE FUTURE
• The lobby of pharmaceutical industry has developed drugs
for business but with a lot of side-effects and deaths (i.e.
Vioxx, Mediator, Depakine) = THE REALITY
• Biotechnology research has no effective results and
applications ! (i.e. Telethon) = THE REALITY
• Human genome decrypted did no bring any advance for
human therapies ! = THE REALITY

8. Editorial reservation in Allergie et Immunologie 1978: an unfair
method to discreditate the research of Bernard Sudan for
« Nicotine as a hapten in passive smoking » !
“We can avoid building a house of cards that will collapse in
the wind of common sense”

9. The causes of editorial reservation and
discreditation…for research of Bernard Sudan on
Nicotine as a hapten in passive smoking and the so-
called seborrheic dermatitis since 1887:
• Before my publication in 1978, nicotine couldn’t
be a hapten ! But after my publication nicotine was
a hapten for vaccine, patch-tests, chewing-gums
and sprays : a good business for pharmaceutical
industry but without results, no double-blind
studies and no editorial reservation !
• Research confirmed by A.L. de Weck and S.Lehrer
• Widely use of topical corticoids after consultations
of dermatologists… (3 – 5 % of population)
• A simple and inexpensive solution: dead sea salts !

10. Samuel Hahnemann : Homeopathy 1796
(clinical observations)
And after 192 years…!
Jacques Benveniste : Digital biology 1988
(Human basophil degranulation test, isolated guinea pig
heart, transatlantic transfert)
Paul G. Unna : « Seborrheic dermatitis » 1887
(sebaceous aspect…)
And after 91 years…!
Bernard Sudan: Hapten nicotine dermatitis 1978
(Human basophil degranulation test, intra-cutaneous test,
specific IgE antibodies, Passive cutaneous anaphylaxis)

11. Nature and the corrrespondence
of Jacques Benveniste
• The opponents of Jacques Benveniste are under the influence
of the pharmaceutical industry: Jean-Marie Lehn was later in
board of Ciba, Basel, Switzerland
• Not a single experiment in biology is reproducible at 100%
• So-called experiments has been organized to discredit reality
(i.e. Hirst, Metzger with their own tests…not as sensitive as
HBDT)
• The electromagnetic environment was not taked into account
(see precautions of Luc Montagnier, France 5 télévision, 2014)
• Opponents did not apply double-blind placebo-controlled
experiments to themselves : i.e. Abelin Th.et al. the Lancet 1989
and Letter to the Editor (Sudan BJL) : « Transdermal nicotine
and placebo ». Their « placebo » contained 1 mg nicotine !
• We are faced to a censorship of the reality and to a new
paradigm !

12. • 1978: Basophil degranulation test as « Baso-Kit »
(Jacques Benveniste) , Stallergènes, Paris
Clin Allergy. 1984 Nov;14(6):571-9.
Evaluation of the human basophil degranulation test using
the commercially available Baso-kit as a test of immediate-
type hypersensitivity in hay-fever sufferers.
Yeung Laiwah AC, Patel KR, Seenan AK, Galloway
E, McCulloch W.
• 2018: Basophil degranulation test as « Baso Test Kit »
San Diego, Ca, USA
Baso Test Kit - Allele Biotechnology
www.allelebiotech.com/basotest-kit-100-tests/
Reagent kit for the quantitative determination of the degranulation of
basophilic granulocytes in heparinized human whole blood.