A recent 15-year epidemiological and clinical researches says that
To a nerve cell, caffeine looks like adenosine: Caffeine binds to the adenosine receptor. Caffeine also causes the brain's blood vessels to constrict,The airway opens up Your heart beats faster.Blood pressure risesBlood flow to the stomach slows.central nervous system (CNS), cardiac muscle and skeletal muscle
Flavonoids are a group of polyphenolic compounds that occur widely in fruits, vegetables, tea, red wine, and chocolateProcessing of cocoa results in 60% loss of total flavonoids.catechin, and epicatechin
A recent 15-year epidemiologicalstudy of elderly Dutch men showed that blood pressure wassignificantly lowered in the group consuming cocoa or chocolate
Radicals are damaged to lipids in cell membrane Free radicals oxidized lipid in cell wall
Atherogenesis is blocking blood vessel Lipids are deposited on blood vessels.Two types of lipids. LDL HDLLdL – bad lipidHDL- good lipidLdl is not harmful in there normal stage.But harmful in oxidized fInhibit LDL oxidationIpoprotion oxidationlipoprotein
after two weeks Taking highly flavanol-enriched cocoa,LDL level decreases of 6%, HDL (good) cholesterol rose by 9
During the six hour time period following intake of cocoa, there was a reduction in adhesion molecules on the surface of the platelets, making the platelets less likely to adhere to other molecules in the bloodstream
Cause hardening of the arteries reduce inflammation cytokines
Several approaches have been used to investigate the mechanismof the action of cocoa flavanoids. These include preclinical, clinicaland in vitro studies predominantly for their effects on the vascularsystem
1998 nobel prizeDecrease vascular oxidant stress by inactivation of super oxideIncreases vasodilation
These amines can affect blood vessels in the brain, triggering a migraine in individuals that are sensitive to the amine. tyramine
Cocoa and chocolate have been reported to exert several effects on human sexualityphenylethylamine, stimulate the hypothalamusIncease the levels of two neurotransmitters likserotoninenhancing mood lifting andsexual drive.
So it use for make cheat girls and make love..She loves chocolet more than youraise blood pressure heart rate, blood glucose levels.
health benefits include unprocessed cocoa, cocoa powder, and dark chocolateLowering LDLAct as antioxidant
Nutrition and health aspects of chocolate
Nutrition And Health
Aspects Of Chocolate
Department of Food Science & Technology
University of Preadeniya
living on islands off
the coast of Panama
increase in blood
because this protection
is lost on migration to
urban Panama City
enormous amounts of
* Fisher, et al. J Hypertens. 2005;23:1453-1459
Health Effects of Chocolate
Increase Insulin sensitivity
Effect on Blood Lipids
Relationship with migraine…
Other Psychoactive Compounds
Cocoa and chocolate contain
relatively low concentrations
of caffeine but about ten times
as much theobromine
Stimulation of the central
nervous system (CNS),
cardiac muscle and skeletal
Relaxation of smooth muscle
Caffeine Theobromine Theophylline
Group of polyphenolic
Cocoa and chocolate
products have the highest
concentration of flavonoids.
Over 10 percent of the weight
of cocoa powder is
Cocoa mainly have catechin,
Chocolate Beans Green tea Apricots Red wine Black tea Cherries Peaches Blackberries Apples Cider
60 50 50
Flavanols/Epicatechin Concentrations In
Cocoa flavanols have the potential to modify a number
of processes involved cardiovascular disease
Improving vascular endothelial
How Chocolate act as Antioxidant
• Atherogenesis initiated by oxidation of the lipid in LDL
termed as lipid per oxidation .
• Oxidized LDL Accumulate in extra cellular sub
• Catechin inhibit the oxidation of low-density lipoprotein
• As the oxidized form of LDL that leads to the buildup of
fatty streak in arteries.
Corti R et al. Circulation 2009;119:1433-1441
Health-relevant effect of epicatechin
It reduces the probability of clotting.
Cocoa reduce adhesion molecules on the surface of the
Result: making the platelets less likely to adhere to other
molecules in the bloodstream
This is the same response that would be seen following
intake of antiplatelet agents such as aspirin
production of inflammatory chemicals (cytokines)
increases the risk of heart disease
That chemicals cause hardening of the arteries and
congestive heart failure
Studies have shown that epicatechin and catechin
molecules reduce inflammation cytokines.
Other Health Issues
Prejudice Reason Truth
Migraine large doses of
only small quantity
Obesity sugar * a lot of sugar
# less sugar no
Acne no correlation between acne and chocolate
Allergy allergy is rare (exception: traces of nuts)
Addiction no evidence proved (only delight and desire)
*cheap, mass-produced chocolate
# dark chocolate (> 70%)
Several effects on human
Increasing sexual desire and
improving sexual pleasure
Phenyl ethylamine stimulate the
Increase levels of two
Eating chocolate gives an
instant energy boost.
Women are more
susceptible to the effects of
phenyl ethylamine and
serotonin than men.
• Forms of chocolate that contain health benefits include
unprocessed cocoa, cocoa powder, and dark chocolate.
• The more processed chocolate is the less healthy it is.
• The cocoa in chocolate contains components that lessen
cholesterol, blood pressure, and therefore, lower chance
of heart failure.
• Healthy components include flavonals, antioxidants,
• Lowering LDL, the bad cholesterol, and lowering blood
pressure directly helps lower the chance of heart failure.
• Chocolate is healthy for you in moderation