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Bacterial corneal ulcer (pathogenesis, pathology, clinical features).

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Bacterial corneal ulcer (pathogenesis, pathology, clinical features).

  1. 1. BACTERIAL CORNEAL ULCER. PATHOGENES IS PATHOLOGY. CLINICAL FEATURES. BY:- DR.AYESHA SARWAR.
  2. 2. BEING THE MOST ANTERIOR PART OF THE EYEBALL, THE CORNEA IS EXPOSED TO ATMOSPHERE AND HENCE PRONE TO GET INFECTED EASILY. AT THE SAME TIME CORNEA IS PROTECTED FROM DAY- TO-DAY MINOR INFECTIONS BY NORMAL DEFENCE MECHANISMS PRESENT IN THE TEARS (Present in the form of lysozyme and other proteins) THERFORE, INFECTIVE BACTERIAL ULCER MAY DEVELOP WHEN:- Either the local defence mechanism is jeopardised. Presence of local ocular predisposing disease. Host’s immunity is compromised. The causative organism is very virulent.
  3. 3. PATHOGENESIS.....
  4. 4. PATHOLOGY OF BACTERIAL CORNEAL ULCER.....
  5. 5. Stages of corneal ulcer (Pathology) Regressive  Progressive Cicatrization Leucocytic infiltration PMN leucocytic infiltration vascularisation
  6. 6. CLINICAL PICTURE (SIGNS AND SYMPTOMS).... A 50year OLD MAN COMES WITH A HISTORY OF........ PAIN AND FOREIGN BODY SENSATION WATERING FROM THE EYE PHOTOPHOBIA BLURRED VISION REDNESS OF EYES. SWOLLEN LIDS. MARKED BLEPHAROSPASM. CHEMOSED CONJUCTIVA. A WELL ESTABLISHED CORNEAL ULCER (characteried by):- Yellowish white area of ulcer...may be oval/irregular. Margins of ulcer oval and overhanging. Floor of the ulcer covered by necrotic material. Stromal oedema present surrounding the ulcer area.

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