SlideShare a Scribd company logo

Gaba ppt

Aya Ali
Aya Ali

This document discusses GABA (gamma-aminobutyric acid), the primary inhibitory neurotransmitter in the mammalian central nervous system. It outlines GABA's mechanism of action via GABA-A and GABA-B receptors, synthesis, functions in relieving anxiety and improving mood, and relationship to health conditions like insomnia, depression, seizures, and panic disorders when deficient. The conclusion states that GABA functions to inhibit nerve impulses by blocking them, preventing nerve cells from firing too often or easily.

1 of 17
Download to read offline
GABA
Aya Ali
431203717

γ-Aminobutyric acid
Outline :
GABA:
 Mechanism of action
 Synthesis.
 Receptors .
 Function .
 Deficiency.

Disease related .
 Conclusion
GABA
GABA acts at inhibitory synapse in the brain by binding to
specific transmembrane receptor in the plasma membrane of
both pre- and postsynaptic neuronal processes.

It is most highly concentrated in the substantia nigra &
globus pallidus nuclei of the basal ganglia, followed by
the hypothalamus, the periaqueductal grey matter.
Fig (1)
Mechanism of Action
open chloride receptorschannels induce cellular
hyperpolarisation by
increasing intracellular
concentration of chloride
Synthesis of GABA

Recommended

More Related Content

What's hot (20)

GABA, glutamate receptors and their modulation
GABA, glutamate receptors and their modulationGABA, glutamate receptors and their modulation
GABA, glutamate receptors and their modulation
 
Aminoacid neurotransimitter
Aminoacid neurotransimitterAminoacid neurotransimitter
Aminoacid neurotransimitter
 
Glycine receptor
Glycine receptorGlycine receptor
Glycine receptor
 
Histamine as a cns neurotransmitter
Histamine as a cns neurotransmitterHistamine as a cns neurotransmitter
Histamine as a cns neurotransmitter
 
Glutamate receptors
Glutamate receptorsGlutamate receptors
Glutamate receptors
 
L-Glutamate
L-GlutamateL-Glutamate
L-Glutamate
 
Gaba modulators
Gaba  modulatorsGaba  modulators
Gaba modulators
 
Acetylcholine - A neurotransmitter
Acetylcholine - A neurotransmitterAcetylcholine - A neurotransmitter
Acetylcholine - A neurotransmitter
 
GABA Receptors
GABA ReceptorsGABA Receptors
GABA Receptors
 
Neuropharmacology: GABA & Glutamate
Neuropharmacology: GABA & GlutamateNeuropharmacology: GABA & Glutamate
Neuropharmacology: GABA & Glutamate
 
Neurohumoral Transmission in CNS
Neurohumoral Transmission in CNSNeurohumoral Transmission in CNS
Neurohumoral Transmission in CNS
 
Receptors
ReceptorsReceptors
Receptors
 
Gaba
GabaGaba
Gaba
 
G- Protein Coupled Receptors
G- Protein Coupled ReceptorsG- Protein Coupled Receptors
G- Protein Coupled Receptors
 
serotonin/neurotransmitter
serotonin/neurotransmitterserotonin/neurotransmitter
serotonin/neurotransmitter
 
NMDA receptors and drugs acting on them
NMDA receptors and drugs acting on themNMDA receptors and drugs acting on them
NMDA receptors and drugs acting on them
 
SEROTONIN (VK)
SEROTONIN (VK)SEROTONIN (VK)
SEROTONIN (VK)
 
Serotonin
SerotoninSerotonin
Serotonin
 
Neurotransmission
NeurotransmissionNeurotransmission
Neurotransmission
 
Neurohumoral Transmission in central nervous system
Neurohumoral Transmission in central nervous systemNeurohumoral Transmission in central nervous system
Neurohumoral Transmission in central nervous system
 

Viewers also liked (15)

Epileptogenesis and drugs ppt
Epileptogenesis and drugs pptEpileptogenesis and drugs ppt
Epileptogenesis and drugs ppt
 
Drugs and the brain
Drugs and the brainDrugs and the brain
Drugs and the brain
 
neurotransmisor gaba
neurotransmisor gaba neurotransmisor gaba
neurotransmisor gaba
 
ANESTESIOLOGIA BASICA: Anestesia general
ANESTESIOLOGIA BASICA: Anestesia generalANESTESIOLOGIA BASICA: Anestesia general
ANESTESIOLOGIA BASICA: Anestesia general
 
Benzodiacepinas
BenzodiacepinasBenzodiacepinas
Benzodiacepinas
 
Benzodiacepinas unsm
Benzodiacepinas unsmBenzodiacepinas unsm
Benzodiacepinas unsm
 
GABA
GABAGABA
GABA
 
Clordiazepoxido
ClordiazepoxidoClordiazepoxido
Clordiazepoxido
 
Neurotransmitter ppt
Neurotransmitter pptNeurotransmitter ppt
Neurotransmitter ppt
 
Neurotrasmisor GABA
Neurotrasmisor GABANeurotrasmisor GABA
Neurotrasmisor GABA
 
Anticonvulsivantes Farmacología Clínica Parte 3
Anticonvulsivantes Farmacología Clínica Parte 3Anticonvulsivantes Farmacología Clínica Parte 3
Anticonvulsivantes Farmacología Clínica Parte 3
 
Benzodiacepinas
BenzodiacepinasBenzodiacepinas
Benzodiacepinas
 
FISIOLOGÍA - NEUROTRANSMISORES
FISIOLOGÍA - NEUROTRANSMISORESFISIOLOGÍA - NEUROTRANSMISORES
FISIOLOGÍA - NEUROTRANSMISORES
 
Anticonvulsivantes
AnticonvulsivantesAnticonvulsivantes
Anticonvulsivantes
 
Anticonvulsivantes.
Anticonvulsivantes.Anticonvulsivantes.
Anticonvulsivantes.
 

Similar to Gaba ppt

Similar to Gaba ppt (20)

GABA.pptx
GABA.pptxGABA.pptx
GABA.pptx
 
GABA (Gamma aminobutyric acid)
GABA (Gamma aminobutyric acid)GABA (Gamma aminobutyric acid)
GABA (Gamma aminobutyric acid)
 
ppt on neuro transmitters
ppt on neuro transmittersppt on neuro transmitters
ppt on neuro transmitters
 
Gaba
Gaba Gaba
Gaba
 
Sedatives and hypnotics
Sedatives  and hypnoticsSedatives  and hypnotics
Sedatives and hypnotics
 
Gaba seminar
Gaba seminarGaba seminar
Gaba seminar
 
Antiepileptic drugs
Antiepileptic drugsAntiepileptic drugs
Antiepileptic drugs
 
Gamma aminobutyric acid (GABA) psychiatry biochemistry
Gamma aminobutyric acid (GABA) psychiatry biochemistryGamma aminobutyric acid (GABA) psychiatry biochemistry
Gamma aminobutyric acid (GABA) psychiatry biochemistry
 
gaba receptor.pptx
gaba receptor.pptxgaba receptor.pptx
gaba receptor.pptx
 
Sedative And Hypnotics
Sedative And Hypnotics Sedative And Hypnotics
Sedative And Hypnotics
 
Gabaergic system by Siddhartha Das
Gabaergic system by Siddhartha DasGabaergic system by Siddhartha Das
Gabaergic system by Siddhartha Das
 
Glutamate seminar
Glutamate seminarGlutamate seminar
Glutamate seminar
 
MANIA , PHARMACOLOGY OF ANTIMANIC DRUGS
MANIA , PHARMACOLOGY OF ANTIMANIC DRUGS MANIA , PHARMACOLOGY OF ANTIMANIC DRUGS
MANIA , PHARMACOLOGY OF ANTIMANIC DRUGS
 
ROLE OF SECOND MESSENGERS IN RECEPTOR SIGNAL TRABSDUCTION
ROLE OF SECOND MESSENGERS IN RECEPTOR SIGNAL TRABSDUCTION ROLE OF SECOND MESSENGERS IN RECEPTOR SIGNAL TRABSDUCTION
ROLE OF SECOND MESSENGERS IN RECEPTOR SIGNAL TRABSDUCTION
 
Pharmacodynamics-II.pptx
Pharmacodynamics-II.pptxPharmacodynamics-II.pptx
Pharmacodynamics-II.pptx
 
Sedative hypnotics-1
Sedative hypnotics-1Sedative hypnotics-1
Sedative hypnotics-1
 
G protein coupled receptors
G protein coupled receptorsG protein coupled receptors
G protein coupled receptors
 
GABA-AT_3
GABA-AT_3GABA-AT_3
GABA-AT_3
 
G protein coupled receptors
G protein coupled receptorsG protein coupled receptors
G protein coupled receptors
 
Viet Hai company
Viet Hai companyViet Hai company
Viet Hai company
 

More from Aya Ali

Arsenic Toxicity
Arsenic Toxicity Arsenic Toxicity
Arsenic Toxicity Aya Ali
 
Acyclovir
AcyclovirAcyclovir
AcyclovirAya Ali
 
Fid ppt(2)
Fid ppt(2)Fid ppt(2)
Fid ppt(2)Aya Ali
 
Ampoules steralization
Ampoules steralizationAmpoules steralization
Ampoules steralizationAya Ali
 
Formal case ( 5 problems duodenal ulcer , hypertension , anemia , smoking , h...
Formal case ( 5 problems duodenal ulcer , hypertension , anemia , smoking , h...Formal case ( 5 problems duodenal ulcer , hypertension , anemia , smoking , h...
Formal case ( 5 problems duodenal ulcer , hypertension , anemia , smoking , h...Aya Ali
 
Formal case Presentation (care plan for patient has duodenal ulcer caused by...
Formal case Presentation (care plan for  patient has duodenal ulcer caused by...Formal case Presentation (care plan for  patient has duodenal ulcer caused by...
Formal case Presentation (care plan for patient has duodenal ulcer caused by...Aya Ali
 

More from Aya Ali (6)

Arsenic Toxicity
Arsenic Toxicity Arsenic Toxicity
Arsenic Toxicity
 
Acyclovir
AcyclovirAcyclovir
Acyclovir
 
Fid ppt(2)
Fid ppt(2)Fid ppt(2)
Fid ppt(2)
 
Ampoules steralization
Ampoules steralizationAmpoules steralization
Ampoules steralization
 
Formal case ( 5 problems duodenal ulcer , hypertension , anemia , smoking , h...
Formal case ( 5 problems duodenal ulcer , hypertension , anemia , smoking , h...Formal case ( 5 problems duodenal ulcer , hypertension , anemia , smoking , h...
Formal case ( 5 problems duodenal ulcer , hypertension , anemia , smoking , h...
 
Formal case Presentation (care plan for patient has duodenal ulcer caused by...
Formal case Presentation (care plan for  patient has duodenal ulcer caused by...Formal case Presentation (care plan for  patient has duodenal ulcer caused by...
Formal case Presentation (care plan for patient has duodenal ulcer caused by...
 

Recently uploaded

Ascariasis.pptx Department of Physiotherapy, SHUATS, Prayagraj
Ascariasis.pptx Department of Physiotherapy, SHUATS, PrayagrajAscariasis.pptx Department of Physiotherapy, SHUATS, Prayagraj
Ascariasis.pptx Department of Physiotherapy, SHUATS, PrayagrajSurabhi Srivastava
 
Measles.pptx Department of Physiotherapy, SHUATS, Prayagraj
Measles.pptx Department of Physiotherapy, SHUATS, PrayagrajMeasles.pptx Department of Physiotherapy, SHUATS, Prayagraj
Measles.pptx Department of Physiotherapy, SHUATS, PrayagrajSurabhi Srivastava
 
Hydrocele and tumors of testis Introduction.pptx
Hydrocele and tumors of testis Introduction.pptxHydrocele and tumors of testis Introduction.pptx
Hydrocele and tumors of testis Introduction.pptxSizan Thapa
 
EUTHANASIA: WORLD AND INDIAN PERSPECTIVEpptx
EUTHANASIA: WORLD AND INDIAN PERSPECTIVEpptxEUTHANASIA: WORLD AND INDIAN PERSPECTIVEpptx
EUTHANASIA: WORLD AND INDIAN PERSPECTIVEpptxDr. Sumit KUMAR
 
Biochemistry of Carbohydrates for MBBS, BDS, Lab Med 2024.pptx
Biochemistry of Carbohydrates for MBBS, BDS, Lab Med 2024.pptxBiochemistry of Carbohydrates for MBBS, BDS, Lab Med 2024.pptx
Biochemistry of Carbohydrates for MBBS, BDS, Lab Med 2024.pptxRajendra Dev Bhatt
 
Cell :Structure & Functions for Medical and Health allied Students
Cell :Structure & Functions for Medical and Health allied StudentsCell :Structure & Functions for Medical and Health allied Students
Cell :Structure & Functions for Medical and Health allied StudentsRajendra Dev Bhatt
 
Materials for Spectacle Lenses​ UG STUDENTS.pptx
Materials for Spectacle Lenses​ UG STUDENTS.pptxMaterials for Spectacle Lenses​ UG STUDENTS.pptx
Materials for Spectacle Lenses​ UG STUDENTS.pptxKAUSAR NAHID
 
Psychedelic Treatment Planning: Opportunities in Integrated Care
Psychedelic Treatment Planning: Opportunities in Integrated CarePsychedelic Treatment Planning: Opportunities in Integrated Care
Psychedelic Treatment Planning: Opportunities in Integrated CareBrian Peacock
 
Tuberculosis .pptx Department of Physiotherapy, SHUATS, Prayagraj
Tuberculosis .pptx Department of Physiotherapy, SHUATS, PrayagrajTuberculosis .pptx Department of Physiotherapy, SHUATS, Prayagraj
Tuberculosis .pptx Department of Physiotherapy, SHUATS, PrayagrajSurabhi Srivastava
 
Malaria Disease.pptx Department of Physiotherapy, SHUATS, Prayagraj
Malaria Disease.pptx Department of Physiotherapy, SHUATS, PrayagrajMalaria Disease.pptx Department of Physiotherapy, SHUATS, Prayagraj
Malaria Disease.pptx Department of Physiotherapy, SHUATS, PrayagrajSurabhi Srivastava
 
RASASHALA IN ACCORDANCE WITH GMP....pptx
RASASHALA IN ACCORDANCE WITH GMP....pptxRASASHALA IN ACCORDANCE WITH GMP....pptx
RASASHALA IN ACCORDANCE WITH GMP....pptxDr. Anusha Baseganni
 
Vertigo and Nystagmus - Clinical approach part-2.pptx
Vertigo and Nystagmus - Clinical approach part-2.pptxVertigo and Nystagmus - Clinical approach part-2.pptx
Vertigo and Nystagmus - Clinical approach part-2.pptxYasser Alzainy
 
Analyzing Performance of the Twist Exome with CNV Backbone at Various Probe D...
Analyzing Performance of the Twist Exome with CNV Backbone at Various Probe D...Analyzing Performance of the Twist Exome with CNV Backbone at Various Probe D...
Analyzing Performance of the Twist Exome with CNV Backbone at Various Probe D...Golden Helix
 
Macquarie Neurosurgery Journal Club 2022 PPT
Macquarie Neurosurgery Journal Club 2022 PPTMacquarie Neurosurgery Journal Club 2022 PPT
Macquarie Neurosurgery Journal Club 2022 PPTMQ_Library
 
Disruption at the Neuromuscular Junction: Relevance of Autoantibodies to Ther...
Disruption at the Neuromuscular Junction: Relevance of Autoantibodies to Ther...Disruption at the Neuromuscular Junction: Relevance of Autoantibodies to Ther...
Disruption at the Neuromuscular Junction: Relevance of Autoantibodies to Ther...PeerVoice
 
Finger Clubbing by Dr. Samuel2 Alawode.pptx
Finger Clubbing by Dr. Samuel2 Alawode.pptxFinger Clubbing by Dr. Samuel2 Alawode.pptx
Finger Clubbing by Dr. Samuel2 Alawode.pptxAlawode Samuel2
 
Poliomyelitis.pptx Department of Physiotherapy, SHUATS, Prayagraj
Poliomyelitis.pptx Department of Physiotherapy, SHUATS, PrayagrajPoliomyelitis.pptx Department of Physiotherapy, SHUATS, Prayagraj
Poliomyelitis.pptx Department of Physiotherapy, SHUATS, PrayagrajSurabhi Srivastava
 
GROSS ANATOMY OF CAECUM & APPENDIX DR VKVS.ppt
GROSS ANATOMY OF CAECUM & APPENDIX DR VKVS.pptGROSS ANATOMY OF CAECUM & APPENDIX DR VKVS.ppt
GROSS ANATOMY OF CAECUM & APPENDIX DR VKVS.pptDr Vinay KV Shetty
 
Physiology of Pituitary gland and its hormones -3.pptx
Physiology of Pituitary gland and its hormones -3.pptxPhysiology of Pituitary gland and its hormones -3.pptx
Physiology of Pituitary gland and its hormones -3.pptxSai Sailesh Kumar Goothy
 
How to be a successful physician intrapreneur
How to be a successful physician intrapreneurHow to be a successful physician intrapreneur
How to be a successful physician intrapreneurArlen Meyers, MD, MBA
 

Recently uploaded (20)

Ascariasis.pptx Department of Physiotherapy, SHUATS, Prayagraj
Ascariasis.pptx Department of Physiotherapy, SHUATS, PrayagrajAscariasis.pptx Department of Physiotherapy, SHUATS, Prayagraj
Ascariasis.pptx Department of Physiotherapy, SHUATS, Prayagraj
 
Measles.pptx Department of Physiotherapy, SHUATS, Prayagraj
Measles.pptx Department of Physiotherapy, SHUATS, PrayagrajMeasles.pptx Department of Physiotherapy, SHUATS, Prayagraj
Measles.pptx Department of Physiotherapy, SHUATS, Prayagraj
 
Hydrocele and tumors of testis Introduction.pptx
Hydrocele and tumors of testis Introduction.pptxHydrocele and tumors of testis Introduction.pptx
Hydrocele and tumors of testis Introduction.pptx
 
EUTHANASIA: WORLD AND INDIAN PERSPECTIVEpptx
EUTHANASIA: WORLD AND INDIAN PERSPECTIVEpptxEUTHANASIA: WORLD AND INDIAN PERSPECTIVEpptx
EUTHANASIA: WORLD AND INDIAN PERSPECTIVEpptx
 
Biochemistry of Carbohydrates for MBBS, BDS, Lab Med 2024.pptx
Biochemistry of Carbohydrates for MBBS, BDS, Lab Med 2024.pptxBiochemistry of Carbohydrates for MBBS, BDS, Lab Med 2024.pptx
Biochemistry of Carbohydrates for MBBS, BDS, Lab Med 2024.pptx
 
Cell :Structure & Functions for Medical and Health allied Students
Cell :Structure & Functions for Medical and Health allied StudentsCell :Structure & Functions for Medical and Health allied Students
Cell :Structure & Functions for Medical and Health allied Students
 
Materials for Spectacle Lenses​ UG STUDENTS.pptx
Materials for Spectacle Lenses​ UG STUDENTS.pptxMaterials for Spectacle Lenses​ UG STUDENTS.pptx
Materials for Spectacle Lenses​ UG STUDENTS.pptx
 
Psychedelic Treatment Planning: Opportunities in Integrated Care
Psychedelic Treatment Planning: Opportunities in Integrated CarePsychedelic Treatment Planning: Opportunities in Integrated Care
Psychedelic Treatment Planning: Opportunities in Integrated Care
 
Tuberculosis .pptx Department of Physiotherapy, SHUATS, Prayagraj
Tuberculosis .pptx Department of Physiotherapy, SHUATS, PrayagrajTuberculosis .pptx Department of Physiotherapy, SHUATS, Prayagraj
Tuberculosis .pptx Department of Physiotherapy, SHUATS, Prayagraj
 
Malaria Disease.pptx Department of Physiotherapy, SHUATS, Prayagraj
Malaria Disease.pptx Department of Physiotherapy, SHUATS, PrayagrajMalaria Disease.pptx Department of Physiotherapy, SHUATS, Prayagraj
Malaria Disease.pptx Department of Physiotherapy, SHUATS, Prayagraj
 
RASASHALA IN ACCORDANCE WITH GMP....pptx
RASASHALA IN ACCORDANCE WITH GMP....pptxRASASHALA IN ACCORDANCE WITH GMP....pptx
RASASHALA IN ACCORDANCE WITH GMP....pptx
 
Vertigo and Nystagmus - Clinical approach part-2.pptx
Vertigo and Nystagmus - Clinical approach part-2.pptxVertigo and Nystagmus - Clinical approach part-2.pptx
Vertigo and Nystagmus - Clinical approach part-2.pptx
 
Analyzing Performance of the Twist Exome with CNV Backbone at Various Probe D...
Analyzing Performance of the Twist Exome with CNV Backbone at Various Probe D...Analyzing Performance of the Twist Exome with CNV Backbone at Various Probe D...
Analyzing Performance of the Twist Exome with CNV Backbone at Various Probe D...
 
Macquarie Neurosurgery Journal Club 2022 PPT
Macquarie Neurosurgery Journal Club 2022 PPTMacquarie Neurosurgery Journal Club 2022 PPT
Macquarie Neurosurgery Journal Club 2022 PPT
 
Disruption at the Neuromuscular Junction: Relevance of Autoantibodies to Ther...
Disruption at the Neuromuscular Junction: Relevance of Autoantibodies to Ther...Disruption at the Neuromuscular Junction: Relevance of Autoantibodies to Ther...
Disruption at the Neuromuscular Junction: Relevance of Autoantibodies to Ther...
 
Finger Clubbing by Dr. Samuel2 Alawode.pptx
Finger Clubbing by Dr. Samuel2 Alawode.pptxFinger Clubbing by Dr. Samuel2 Alawode.pptx
Finger Clubbing by Dr. Samuel2 Alawode.pptx
 
Poliomyelitis.pptx Department of Physiotherapy, SHUATS, Prayagraj
Poliomyelitis.pptx Department of Physiotherapy, SHUATS, PrayagrajPoliomyelitis.pptx Department of Physiotherapy, SHUATS, Prayagraj
Poliomyelitis.pptx Department of Physiotherapy, SHUATS, Prayagraj
 
GROSS ANATOMY OF CAECUM & APPENDIX DR VKVS.ppt
GROSS ANATOMY OF CAECUM & APPENDIX DR VKVS.pptGROSS ANATOMY OF CAECUM & APPENDIX DR VKVS.ppt
GROSS ANATOMY OF CAECUM & APPENDIX DR VKVS.ppt
 
Physiology of Pituitary gland and its hormones -3.pptx
Physiology of Pituitary gland and its hormones -3.pptxPhysiology of Pituitary gland and its hormones -3.pptx
Physiology of Pituitary gland and its hormones -3.pptx
 
How to be a successful physician intrapreneur
How to be a successful physician intrapreneurHow to be a successful physician intrapreneur
How to be a successful physician intrapreneur
 

Gaba ppt