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The popularity of additive manufacturing in the medical device manufacturing industry is growing thanks to the ability to print solid substrate and lattice structure for implant fixation in a single step. Printing a lattice structure is not only a matter of design, but it also requires the ability to process the foam-like structure in a way that make it usable in the human body. Cleaning, in this specific case, removes loose particles and/or contaminants from such structures. To achieve this objective, a mechanical and dry step has been developed to remove the majority of loose particles without adding any substance to the lattice structure. Following steps based on chemical etching of the titanium surface on a lattice structure can be used to remove the remaining particles and to modify the structures’ surfaces to enhance osteoconductivity. Where machining lubricants must be removed, we are seeing promising results in developing a proper cleaning step with specific detergents, which avoids any detectable residual in the foam but is capable of completely removing contaminants.