Analytical methods are generally delivered in the form of documents describing the method in terms of analytes which can be studied, supported matrices, reagents, methodological details, statistical performance, interlaboratory validation and other details. Regulatory bodies including the US Environmental Protection Agency (US-EPA), US Geological Survey (USGS), US Department of Agriculture (USDA) and others provide detailed analytical methods for the community to adopt in their analyses. Rich sources of historical analytical data are also available for the community to access and include the US-EPA Environmental Chemistry Methods (https://www.epa.gov/pesticide-analytical-methods/environmental-chemistry-methods-ecm) provided by manufacturers from the agrochemical industry. Instrument vendors also provide access to many hundreds of application notes which can be considered as summary analytical methods, albeit descriptive of particular instruments. This poster describes a cheminformatically-enabled database of methods integrating chemicals related data, extracted from the methods, with the identifiers (names and/or chemical abstracts registry numbers (CASRNs)) mapped to chemical structures. The resulting database of almost 3000 methods can be searched by chemical name, CASRNs, structure and similarity of chemical structure. The resulting database has been integrated into a web-based application and includes integration to public domain mass spectral data and filtering of the methods based on analyte, chemical class, method source and other related metadata.