National Cancer Institute


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National Cancer Institute

  1. 1. caBIG™ Enterprise Support Network Leslie K. Derr, Ph.D. National Cancer Institute Center for Biomedical Informatics and Information Technology
  2. 2. Background: Pilot  Enterprise <ul><li>caBIG Pilot </li></ul><ul><ul><li>Building Community </li></ul></ul><ul><ul><li>Delivering Products </li></ul></ul><ul><ul><li>Real Solutions to Real Problems </li></ul></ul><ul><li>caBIG Enterprise </li></ul><ul><ul><li>Expand Community of stakeholders </li></ul></ul><ul><ul><li>Drive the development and adoption of interoperable tools, standards and infrastructure to facilitate the sharing and integration of data </li></ul></ul>
  3. 3. ESN Purpose <ul><li>Facilitate the widespread adoption of caBIG™ standards, tools and infrastructure </li></ul><ul><li>Expand the support structure for end users beyond the Workspaces, caBIG Program Staff and NCI CBIIT </li></ul>
  4. 4. ESN Defined <ul><li>A collection of diverse organizations that with guidance from the NCI, caBIG Program staff, and caBIG workspaces will expand and support the caBIG community by providing appropriate services, mentoring and expertise </li></ul>
  5. 5. ESN Components <ul><li>caBIG Knowledge Centers </li></ul><ul><li>caBIG Service Providers </li></ul><ul><li>caBIG Program Offices </li></ul>
  6. 6. caBIG™ Knowledge Centers <ul><li>Groups working under NCI-funded contract to serve as a knowledge resource and provide limited levels of support </li></ul><ul><li>Demonstrated expertise in the domain or area of focus </li></ul><ul><li>External outreach to facilitate the widespread adoption of caBIG standards, tools and infrastructure across biomedical research enterprise </li></ul><ul><li>Advance and codify subject matter expertise within a specific domain to deepen and broaden caBIG capabilities </li></ul>
  7. 7. caBIG™ Service Providers <ul><li>Provide comprehensive technical and end-user support </li></ul><ul><ul><li>Service Agreements are negotiated between the Service Provider and the Customer </li></ul></ul><ul><li>3 rd party entities approved by NCI as meeting specific criteria for performance in one or more service areas </li></ul><ul><ul><li>Help Desk and Phone Support </li></ul></ul><ul><ul><li>Software Development </li></ul></ul><ul><ul><li>Implementation Support </li></ul></ul><ul><ul><li>Documentation and Training Development and Delivery </li></ul></ul>
  8. 8. caBIG™ Program Offices <ul><li>May be partially funded by the NCI </li></ul><ul><li>Established at institutions and organizations interested in deploying caBIG tools and infrastructure across multiple departments within an institution or broadly across an organization </li></ul><ul><li>Coordinate efforts so that caBIG can serve as an integrating technology platform </li></ul>
  9. 9. Recipients of ESN <ul><li>Current caBIG community and broader biomedical research community </li></ul><ul><li>Supports the needs of individuals, institutions and organizations adopting caBIG standards, applications, and infrastructure, including IT administrators, end users, administrators and senior decision makers </li></ul>
  10. 10. Centrality of the caBIG Workspace <ul><li>Serve as a Forum for all Stakeholders </li></ul><ul><ul><li>NCI </li></ul></ul><ul><ul><li>caBIG Program Staff </li></ul></ul><ul><ul><li>Developers </li></ul></ul><ul><ul><li>Adopters </li></ul></ul><ul><ul><li>Subject Matter Experts </li></ul></ul><ul><ul><li>Patient Advocates </li></ul></ul><ul><ul><li>KC Representative </li></ul></ul><ul><ul><li>Service Providers </li></ul></ul><ul><ul><li>Pharma, biotech, etc. </li></ul></ul>
  11. 11. Centrality of the caBIG Workspace (cont’d) <ul><li>Activities of Workspace </li></ul><ul><ul><li>Provide the key forum for stakeholders/ information exchange </li></ul></ul><ul><ul><li>Identify needs </li></ul></ul><ul><ul><li>Identify requirements </li></ul></ul><ul><ul><li>Determine priorities </li></ul></ul><ul><ul><li>Set strategic direction of WS </li></ul></ul><ul><ul><li>Bug detection </li></ul></ul><ul><ul><li>Required/desired enhancements </li></ul></ul><ul><ul><li>Open Development and testing </li></ul></ul>
  12. 12. Knowledge Centers currently proposed <ul><li>Tissue Biospecimen/Banking Tools </li></ul><ul><li>Clinical Trials Management Systems </li></ul><ul><li>Molecular Analysis Tools </li></ul><ul><li>caGrid </li></ul><ul><li>Compatibility </li></ul><ul><li>Data Sharing and Intellectual Capital </li></ul>
  13. 13. caBIG™ Knowledge Centers <ul><li>What They Provide </li></ul><ul><li>No cost support to the end-user community </li></ul><ul><li>Stable, predictable, and publicly-available repository for caBIG technology and information base </li></ul><ul><ul><li>Versioned source code </li></ul></ul><ul><ul><li>Comprehensive documentation </li></ul></ul><ul><ul><li>New code committed by the community </li></ul></ul><ul><ul><li>Domain expertise </li></ul></ul><ul><ul><li>Forums and responses </li></ul></ul><ul><ul><li>Domain-relevant training/ train the trainer </li></ul></ul><ul><li>Authoritative, stable and publicly-available repository of policies and standards </li></ul><ul><li>Infrastructure for an open source development community </li></ul><ul><li>Community Outreach – supporting the goals and advancing the work of caBIG </li></ul><ul><li>All software and documentation will be delivered to and housed on NCI-controlled server </li></ul>
  14. 14. caBIG™ Service Providers <ul><ul><li>What They Provide </li></ul></ul><ul><ul><li>3 rd party support of end-user community </li></ul></ul><ul><ul><li>On-site installation and integration of caBIG tools </li></ul></ul><ul><ul><li>Data extraction, translation, and loading based on caBIG standards </li></ul></ul><ul><ul><li>Time-critical end user support </li></ul></ul><ul><ul><li>caBIG tool customization </li></ul></ul><ul><ul><li>On-demand end user training </li></ul></ul>
  15. 15. caBIG™ Program Offices <ul><li>What They Provide </li></ul><ul><li>Capacity to provide on site expertise and points of contact to manage caBIG technology deployments for defined institution or organization </li></ul><ul><li>Broad-based caBIG knowledge management </li></ul><ul><li>Coordination of tool workflow integration </li></ul><ul><li>Technology education and tutorials </li></ul><ul><li>Coordination of inter-departmental technology usage </li></ul><ul><li>Communication of new caBIG program and technology updates </li></ul><ul><li>Monitoring and reporting of caBIG usage and adoption </li></ul>
  16. 16. Software Development Shrink wrap and provide full-featured applications from caBIG-funded reference implementations Customize applications to meet individual user needs Speculative development based on workspace discussions/end-user needs Service Provider Minor enhancements to existing software based upon WS priorities Custodian of software code base maintained in dynamic fashion Foster open development Knowledge Center Identify needs and requirements Set priorities within the domain for new reference implementations – competitive RFP Identify bugs in existing software Define minor and major (competitive RFP) enhancements required/desired for existing software, and determine the priorities Needs/Priorities of the WS will reflect the general needs of the community Workspace
  17. 17. Documentation and Training Tailor documentation and training for specific user groups Provide on-demand training Service Provider Maintaining current supporting documentation and training for existing tools within their domain Post outreach and educational materials on Website Create model documents, position papers, training to meet requirements and strategic priorities of workspace Knowledge Center Awardee is responsible for creating documentation and training for caBIG funded development Develop requirements for model documents, position papers, best practices (if complex or specialized – competitive RFP) Workspace
  18. 18. Traversing the ESN <ul><li>Case Study: Principal Investigator (PI) needs a biospecimen repository </li></ul><ul><li>Contacts caBIG Program Office (PO) </li></ul><ul><li>PO staff point PI to Tissue/Biospecimen Banking Tools Knowledge Center (KC) </li></ul><ul><li>PI visits KC website, discovers caTissue fulfills needs, downloads software and associated documentation </li></ul><ul><li>PI contacts caBIG designated Service Provider to assist with installation and data migration </li></ul><ul><li>After using caTissue for several months, PI desires additional functionality </li></ul><ul><li>Contacts KC where a number of options are presented </li></ul><ul><ul><li>Participation in TBPT WS where needs are identified and priorities set </li></ul></ul><ul><ul><li>Negotiation with caBIG Service Provider for custom enhancement </li></ul></ul><ul><li>PO office canvasses across institution to identify other PIs with common need </li></ul>
  19. 19. Pilot Enterprise Adopter (EA) Program <ul><li>Short term program to assist IT administrators and application end users integrate caBIG tools and infrastructure in support of their research efforts </li></ul><ul><ul><li>Tissue/Biospecimen Banking – caTissue Adoption </li></ul></ul><ul><ul><li>Clinical Trials Data Management -C3D Adoption </li></ul></ul>
  20. 20. Enterprise Adopters <ul><li>Enterprise Adopters: caBIG™ Software Integration Support </li></ul><ul><li>Application End Users and IT Administrators Receive </li></ul><ul><li>Helpdesk telephone support </li></ul><ul><li>Technical support provided by caBIG™ program representatives and partners </li></ul><ul><li>On-site support from caBIG™ application development teams, if appropriate </li></ul><ul><li>Support through funded attendance, as appropriate, at Application End-User Meetings </li></ul>
  21. 21. Enterprise Adopters <ul><li>Enterprise Adopters: caBIG™ Software Integration </li></ul><ul><li>Are expected to </li></ul><ul><li>Integrate caBIG™ tools into their workflow in support of their research efforts </li></ul><ul><li>Share a pre-defined data set used in adoption activities through caBIG™ silver-compatible APIs or caGrid-enabled data services </li></ul><ul><li>Provide a written summary of lessons learned </li></ul><ul><li>Currently being piloted with TBPT suite of tools </li></ul>
  22. 22. Cancer Central Clinical Database (C3D ) Adoption <ul><li>Enterprise Adopters: C3D Integration Support </li></ul><ul><li>Application End Users and IT Administrators Receive </li></ul><ul><li>Helpdesk telephone support </li></ul><ul><li>C3D user licenses for use i n cancer studies only </li></ul><ul><li>Electronic Case Report Form (eCRF) templates, co-branded with the C3D Adopter’s logo(s) </li></ul><ul><li>Oracle Clinical Remote Data Capture (RDC) and Protocol Builder training for cancer clinical research team members </li></ul><ul><li>Cancer Data Standards Repository (caDSR) training </li></ul><ul><li>Standards implementation and Common Data Element (CDE) /template selection assistance for 1-2 studies </li></ul><ul><li>eCRF annotation assistance for 1-2 pilot studies </li></ul><ul><li>CDE curation services </li></ul><ul><li>Protocol Building services for 1-2 cancer clinical research studies </li></ul><ul><li>CTMS Best Practices Documentation </li></ul>
  23. 23. Cancer Central Clinical Database (C3D ) Adoption <ul><li>Enterprise Adopters: C3D Integration Support </li></ul><ul><li>Are expected to </li></ul><ul><li>Integrate C3D into their workflow in support of their cancer clinical research efforts </li></ul><ul><li>Embrace and apply recommended caBIG standards (CDEs, template forms and procedures, development guidelines, etc.) and contribute suggestions for their enhancement as appropriate </li></ul><ul><li>Make a pre-defined set of data stored in or generated through the use of C3D accessible for sharing through caBIG™ silver-compatible application programming interfaces (API) or caGrid-enabled data services, subject to applicable regulations and IRB requirements </li></ul>
  24. 24. Supporting the caBIG™ Enterprise What Who Program Offices Service Providers caBIG™ Enterprise <ul><li>3 rd party entities </li></ul><ul><li>Services open to all caBIG™ institutions </li></ul><ul><li>Comprehensive technical and end-user support </li></ul><ul><li>caBIG™ teams set-up within institutions or organizations </li></ul><ul><li>Services focused within the institution or organization </li></ul><ul><li>Coordinate caBIG™ efforts within institution or across organization </li></ul>Knowledge Centers caBIG Workspace: Key Stakeholder Forum Identifying Needs, Determining Requirements, Setting Priorities Ongoing Tool Development, Adoption and Participation <ul><li>Domain experts </li></ul><ul><li>Services open to all caBIG™ institutions </li></ul><ul><li>Expertise in a specific domain or area of focus </li></ul>