Medical Devices: CZK26.51n (US$1.50bn) in 2011 to CZK26.91bn (US$1.43bn) in 2012; +1.5% in local currency terms and -4.6% in US dollar terms. Forecast moderat ely down due to macroeconomic factors.

1. The Pharmaceutical Market: Czech Republic
OVERVIEW OF THE PHARMACEUTICAL MARKET IN CZECH REPUBLIC
The recent measures proposed by the Czech Republic's Ministry of Health will, in all likelihood, negatively affect the Czech pharmaceutical market. The
introduction of reimbursement ceilings, blind bidding auctions and preferential prescribing will squeeze drugmakers' margins and shift some of the burden of
healthcare spending onto the private sector. The outcome of similar measures in Hungary and Poland strongly supports our view that the business environment
for drugmakers will worsen if these proposals are adopted. It is patients who, ultimately, will suffer.
Headline Expenditure Projections
Pharmaceuticals: CZK80.71bn (US$4.56bn) in 2011 to CZK79.76bn (US$4.2bn) in 2012; -1.2% in local currency terms and -7.1% in US dollar terms.
Healthcare: CZK298.49bn (US$16.88bn) in 2011 to CZK297.87bn (US$15.831bn) in 2012; +0.4% in local currency terms and -8.4% in US dollar terms.
Medical Devices: CZK26.51n (US$1.50bn) in 2011 to CZK26.91bn (US$1.43bn) in 2012; +1.5% in local currency terms and -4.6% in US dollar terms. Forecast
moderat ely down due to macroeconomic factors.
Risk/Reward Rating
The Czech Republic retains its leading position in the CEE RRRs in Q113, after displacing Poland in our Q412 assessment. Despite leading in our regional RRR
table, the outlook for growth for the Czech pharmaceutical market is not particularly robust, as a result of pricing pressure, impeded market entry and increasing
generic substitution. An increase in VAT and a stringent reference pricing system have affected sales and hit manufacturers' margins respectively.
Competitive Landscape
The competitive landscape section provides comparative company analyses and rankings by US$ sales and % share of total sales - for the total pharmaceutical
sector, as well as the OTC, generics, and distribution sub-sectors
table Of Contents
executive Summary 7
swot Analysis 9
czech Republic Pharmaceuticals And Healthcare Industry Swot 9
czech Republic Political Swot 10
czech Republic Economic Swot 10
czech Republic Business Environment Swot 10
pharmaceuticals Risk/reward Ratings 11
table: Central And Eastern Europe Pharmaceuticals Risk/reward Ratings, Q213 11
rewards 12
risks 12
czech Republic - Market Summary 14
regulatory Regime 16
intellectual Property Environment 16
prescribing Rules 17
pharmaceutical Advertising 17
The Pharmaceutical Market: Czech Republic

2. pricing Regime 18
reimbursement Regime 19
recent Pricing And Reimbursement Developments 20
changes To Vat 22
table: European Vat Rates On Medicines (%) 23
industry Developments 25
epidemiology 25
healthcare Sector 26
healthcare Insurance 26
healthcare Reforms 27
hospital Sector 28
research & Development Sector 29
clinical Trials 30
medical Devices 31
industry Forecast Scenario 33
overall Market Forecast 33
table: Czech Pharmaceutical Sales, Historical Data And Forecasts 34
key Growth Factors - Industry 35
table: Czech Healthcare Expenditure Trends, Historical Data And Forecasts 36
table: Czech Government Healthcare Expenditure Trends, Historical Data And Forecasts 37
table: Czech Private Healthcare Expenditure Trends, Historical Data And Forecasts 37
key Growth Factors - Macroeconomic 38
prescription Drug Market Forecast 42
table: Czech Prescription Drug Market Indicators, Historical Data And Forecasts 43
patented Drug Market Forecast 44
table: Czech Patented Drug Market Indicators, Historical Data And Forecasts 45
generic Drug Market Forecast 46
table: Czech Generics Drug Market Indicators, Historical Data And Forecasts 46
The Pharmaceutical Market: Czech Republic

3. otc Medicine Market Forecast 48
table: Czech Over-the-counter (otc) Medicine Market Indicators, Historical Data And Forecasts 50
pharmaceutical Trade Forecast 51
table: Czech Pharmaceutical Trade Data And Forecasts (us$mn) 52
table: Czech Pharmaceutical Trade Data And Forecasts (czkmn) 52
other Healthcare Data Forecasts 53
key Risks To Bmi's Forecast Scenario 53
competitive Landscape 54
pharmaceutical Sector 54
foreign Pharmaceutical Players 55
company Developments 55
pharmaceutical Wholesale 56
pharmaceutical Retail 57
table: Retail Pharmacy Market Overview, 2004-2010 57
pharmaceutical Distribution Developments 59
distance Selling Of Pharmaceuticals 60
company Profiles 61
local Companies 61
zentiva (sanofi) 61
walmark 64
multinational Companies 67
astrazeneca 67
bristol-myers Squibb 68
sanofi 69
novartis 71
glaxosmithkline 72
The Pharmaceutical Market: Czech Republic

4. pfizer 74
demographic Outlook 75
table: Czech Republic's Population By Age Group, 1990-2020 ('000) 76
table: Czech Republic's Population By Age Group, 1990-2020 (% Of Total) 77
table: Czech Republic's Key Population Ratios, 1990-2020 78
table: Czech Republic's Rural And Urban Population, 1990-2020 78
glossary 79
bmi Methodology 81
how We Generate Our Pharmaceutical Industry Forecasts 81
pharmaceuticals Risk/reward Ratings Methodology 82
ratings Overview 82
table: Pharmaceutical Business Environment Indicators 83
weighting 84
table: Weighting Of Components 84
sources 84
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The Pharmaceutical Market: Czech Republic