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Hemostasis is the procedure of interaction between blood vessels, platelets and coagulation protein to stop bleeding. Sometimes, bleeding disorder occurs due to vascular and coagulation abnormalities. These abnormalities could be inherited or acquired. Acquired disorders are the most common by far, majorly thrombocytopenia and other abnormalities include trauma, anticoagulant rodenticide, vitamin K deficiency, disseminated intravascular coagulation (DIC), Von Willebrand disease (vWD), deficiency of intrinsic and extrinsic factors, dysfibrinogenemia, Monoclonal Gammopathy and congenital platelet function defect.