Micro Nutrient Fortification

818 views

Published on

"Micro Nutrient Fortification" from the Regional Conference on Micronutrient Fortification of Foods 2013 (10 ~ 11 October 2013 in Bangkok, Thailand)

Published in: Education
0 Comments
2 Likes
Statistics
Notes
  • Be the first to comment

No Downloads
Views
Total views
818
On SlideShare
0
From Embeds
0
Number of Embeds
176
Actions
Shares
0
Downloads
0
Comments
0
Likes
2
Embeds 0
No embeds

No notes for slide

Micro Nutrient Fortification

  1. 1. !"#$%&'()**+(,-. #/$*&0$1$/(.$2*/0%2+( 34#3(#%50-*670(87$6(9*'$%&
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
  3. 3. !"#$%&'($")&(*+%$("+"#,("%&* -..*/%0'&(,$1*2*3,&4,(%$1 3
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
  6. 6. ! ! ?@"052/1)&* )0"#$"%&'()'/362"%+&#1))0&1%) &*%/#)"552+/$)%&)%8/)*&'%+*+,"%+&#)&* )*&&$)7+%8) 0+,'&#6%'+/#%1)"'/) " +&$+#/:)+'&#:).+%"0+#)A:)"#$)+#,'/"1+#32() *&2+,)",+$ B"1+,),&00&$+%+/1)"'/)0&'/)16+%/$)%&)0"11) *&'%+*+,"%+&# " +#%/#$/$)%&)'/",8)%8/)78&2/)5&562"%+&# 6
  7. 7. ! ! ! ! !"#$%&'"()*+#,%*(-,-.)(-%"/#(01#,%%2# !"#$%&'"()*+#,%*(-,-.)(-%"/#(01#,%%2# $%&'"()*+#,%*(-,-.)(-%" 3)"',).('*1*#,*11&+#.0%%414#(%#,%*(-,+# 3)"',).('*1*#,*11&+#.0%%414#(%#,%*(-,+# 5)*(-.'&)*#,%%24#-"#*145%"41#(%#51*3-44-%"# 6-$1"#-"#,%%2#&)7 !351('4#4(134#,*%3#-"2'4(*+#8#.%"4'31*4# 4119-"6#(%#-".*1)41#3-.*%"'(*-1"(#-"()91 " 4%31#(-314#6%$1*"31"(#5*%$-214#(01# 2*-$-"6#,%*.1 :%$1*"31"(4#0)$1#)#2'(+#(%#1"4'*1#(0)(# :%$1*"31"(4#0)$1#)#2'(+#(%#1"4'*1#(0)(# .%"4'31*4#)*1#"%(#3-4&12#%*#21.1-$12#;+# .%"4'31*4#)*1#"%(#3-4&12#%*#21.1-$12#;+# ,%*(-,-.)(-%"#5*).(-.14 <'4(#;1#4)(-4,-12#(0)(#3)*91(#5*%3%(-%"#%, # ,%*(-,-12#,%%24#2%14#"%(#.%",&-.(#7-(0/#%*# ,%*(-,-12#,%%24#2%14#"%(#.%",&-.(#7-(0/#%*# 2%14#"%(#.%",&-.(#7-(0 .%35*%3-41/#)"+#")(-%")&#,%%2#)"2#"'(*-(-%"# 5%&-.-14#%"#01)&(0+#1)(-"6 7
  8. 8. ! =112#(%#*16'&)(1#(01#*)"61#%, #,%%24#1&-6-;&1# ,%*#$%&'"()*+#,%*(-,-.)(-%"#)"2#%"#(01# 51*3-((12#.%3;-")(-%"4#%, #5)*(-.'&)*# 3-.*%"'(*-1"(4#)"2#,%%24 ! >%*#)"+#6-$1"#5%5'&)(-%"#6*%'5#(01*1#)*1# 41$1*)&#91+#.%"4-21*)(-%"4#(0)(#(%61(01*# 21(1*3-"1#701(01*#3)"2)(%*+#%*#$%&'"()*+# ,%*(-,-.)(-%" -4#&-91&+#(%#;1#(01#3%4(# )55*%5*-)(1#%5(-%"#,%*#(01#5*1$)-&-"6# .%"2-(-%"4 8
  9. 9. !"#$%&#' &$(%)%*+,+-#*&,*.& )#/("%)&#' &(%'%(%*"%) 9
  10. 10. ! ! ! 0#+1&2#3/*+,(4&,*.&5,*.,+#(4& 5-"(#*/+(-%*+&'#(+-'-",+-#*&$(#6(,55%)&%7-)+& -*&"#/*+(-%)&-*&!#/+1%,)+&8)-,9&6#2%(*%.&:4& )$%"-'-"&(%6/3,+-#*);& <1-)&$(%)%*+,+-#*&$(#2-.%)&,*&#2%(2-%=&#' & +1%&)+,+/)&#' &+1%)%&(%6/3,+-#*)&,*.& "1,33%*6%)&-*&-5$3%5%*+-*6&+1%5 !#/("%&#' &-*'#(5,+-#*& " >?!>&!@8&A%6-#*&$/:3-",+-#*&BCDEEF& " ,)&=%33&,)&5#(%&(%"%*+&.#"/5%*+)&'(#5& =%:)-+%)&#' &+1%&(%6/3,+#(4&,6%*"-%) 10
  11. 11. !"#!$#%&$'()*+,$ -./0(1$+2 $ /().345+/1$ -545.-$+2 $ 6*7/+,.5/*(,5$ 2+/5*2*745*+,$*,$ 2++8-$9:;<<= 2++8-$9:;<<= 11
  12. 12. ! #./0(1$7+0(/-$/().345+/1$-545.-$*,> !"#$%&'()"#**)+), /),012&) 6$21$%*&) 9)1* -)+).*&) ! -.)$,)" 34&+&55&$%* 7&$8)51"% :4)&+)$2 ;&%<$), ?@/(($51A(-$+2 $2+/5*2*745*+,$/().345*+,4= 488/(--*,)$,.5/*(,5$8(2*7*(,7*(-$ 964,845+/1$2+/5*2*745*+,= B= 0+3.,54/1$488*5*+,$+2 $,.5/*(,57= /(345(8$,.5/*(,5$7+,5(,5$734*612
  13. 13. !"#$%&'()*+,'&'$,+(- + .(%$/'&)*+-()'0-01&'0(/ 13
  14. 14. ! ! 2&%&*,0&+&%%(3,+&440'0(/+(- +5/$')0"/',6+'(+-((4 2&%&*,0&+&%%(3,+&440'0(/+(- +5/$')0"/',6+'(+-((4 " '(+078)(."+/$')0'0(/&%+.&%$"+(- +'9"+-((4 " 8(,0'0."+%0,'+(- +8")70''"4+5/$')0"/',6 " 0/1%$40/#+.0'&70/,:+70/")&%,:+&70/(+&104,:+ 0/1%$40/#+.0'&70/,:+70/")&%,:+ .0'&70/,:+70/")&%,:+&70/(+&104,:+ -&''*+&104,:+('9")+-((4+1(78(/"/', ;8"10-01+)"#$%&'0(/+-()+701)(/$')0"/'+ -()'0-01&'0(/ " -()+,".")&%+1&'"#()0",+(- +-((4,+<=)"&4:+ -()+,".")&%+1&'"#()0",+(- +-((4,+<=)"&4:+ =)"&>-&,'+1")"&%,:+1(/4"/,"4+70%>:+70%>+ 8(34"):+7&%'"4+70%>+8(34"):+"?&1'+(- +7"&':+ -%($):+('9")+,(%04+-((4,+&/4+%0@$04+-((4,A " /$')0"/',+8")70''"4+-()+5-()'0-01&'0(/6+1%&07B+ /$')0"/',+8")70''"4+-()+5-()'0-01&'0(/6+1%&07B+ .0'&70/,+C:+DE:+DF:+DG:+=0('0/:+8&/'('9"/01+ &104:+/0&10/:+H:+I:+J:+-(%01+&104:+DEFK+ 1&%10$7:+0(40/":+0)(/:+89(,89()$, 14
  15. 15. ! !"#$%&'()*+,"-+#".*/#+,&)#*$,)"-+#)*-*/()*+, " (")(0'$"1)*2&'()$1".*,*.&."(.+&,)"+- ")3$" (")(0'$"1)*2&'()$1".*,*.&."(.+&,)"+4*)(.*,"+#".*,$#(' )+"0$"2#$1$,)")+"/'(*." )+"3(4$"0$$,"$,#*/3$56"-+#)*-*$56" 4*)(.*,*1$5"1&22'$.$,)$5"+#" 1)#$,%)3$,$5"+#"7+#51"+- "1*.*'(#" .$(,*,% " .(8*.&."(.+&,)"+- ")3$"4*)(.*,1"(,5" .(8*.&."(.+&,)"+.*,$#('1")3()".(9"0$"2#$1$,)"*,"5(*'9" 1$#4*,%1"1)*2&'()$5"*,"("1$2(#()$":(0'$ 15
  16. 16. ! ;('(91*("*1"#$4*$7*,%")3*1"#$%&'()*+," ;('(91*("*1"#$4*$7*,%")3*1"#$%&'()*+," 1)*2&'()*,%".*,*.&."(,5".(8*.&."'$4$'1"-+#" .*/#+,&)#*$,)"-+#)*-*/()*+, " ("2+1*)*4$"+&)/+.$"+- "("<=><"1$.*,(#"(,5" "("<=><"1$.*,(#"(,5" 7+#?13+2"+,"@A"B/)+0$#"CA@C " )3$1$"#$D&*#$.$,)1"E$1)(0'*13$5"*,"@FGHI" ,$$5")+"0$"#$4*$7$5J&25()$5"*," (//+#5(,/$"7*)3"/&##$,)"1/*$,/$ " (,"K5"L+/"M+..*))$$"$1)(0'*13$5" /+.2#*1*,%"(''"1)(?$3+'5$#1" (''"1)(?$3+'5$#1"N /+.2#*1*,%"(''"1)(?$3+'5$#1"N %+4$#,.$,)6" (/(5$.*(6"2#+-$11*+,('"0+596"*,5&1)#96"<=>< " $82$/)$5")+"/+.2'$)$"*)1")(1?"(,5" $82$/)$5")+"/+.2'$)$"*)1")(1?"(,5" /+.2'$)$"*)1")(1?" #$/+..$,5"(.$,5.$,)1")+")3$"#$%&'()*+,1" 0$-+#$"9$(#"$,5 16
  17. 17. ! ! !"#"$%&"'()*+&,%'-.,*&)/,'01/,)/,'0#"&+%'2 !"#"$%&"'()*+&,%'-.,*&)/,'01/,)/,'0#"&+%'2 '"001*7&/4',1'817)9'0*&,)*&" 3&43'&/5'%1.*0)'16 '"001*7&/4',1'817)9'0*&,)*&" " :1*'0#"&+'16 ';%1.*0)'16<'5'",'#)"%,'=>?'16 ' -@A'()*'=BB4'C%1#&7%D'16 'EF>?'16 '-@A'()*' =BB'+#'C#&G.&7%D' " :1*'0#"&+'16 ';3&43'&/<5'",'#)"%,'H',&+)%',3)' I"#.)%'61*';%1.*0)'16<' -1,'()*+&,,)7',1'0#"&+';(*)%)/0)'16<5';J&,3<5' ),0'61*'+&0*1/.,*&)/,%'"77)7 !KL'CHB=HDF':117'@)4.#",&1/%'!"#"$%&"'=MN>'"/7' "%%10&",)7'"+)/7+)/,%F' 17
  18. 18. O/71/)%&" !-.,*&)/,'01/,)/,'0#"&+'61*'I&,"+&/%'"/7' +&/)*"#% " 61*'0#"&+';%1.*0)'16<P'+.%,'01/,"&/'",'#)"%,' 61*'0#"&+';%1.*0)'16<P' ;%1.*0)'16<P'+.%,'01/,"&/'",'#)"%,' =>?'QRS'CO/71/)%&"/'-@AD'()*'=BB'4'61*' =>?'QRS'CO/71/)%&"/'-@AD'()*'=BB'4'61*' %1#&7%'"/7'EF>?'QRS' EF>?'QRS'()*'=BB'+#'61*'#&G.&7% %1#&7%'"/7'EF>?'QRS'()*'=BB'+#'61*'#&G.&7% " 61*'0#"&+%'16 ';3&43'&/<'T +.%,'01/,"&/'",' ';3&43'&/<' ;3&43'&/<'T #)"%,',J&0)',3)'I"#.)'61*';%1.*0)'16< 18
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
  22. 22. QA"B"&&"#)D ! W#+)(*1A)*!%#$X%& W#+)(*1A)*!%#$X%& Q"#'5 !)%B*Q('$(%0*F!Q!QH*1A)* ?OP*)#3'-(%$)D*1A)* ?OP*)#3'-(%$)D*1A)* 2'(1"2"3%1"'#*'2 2'(1"2"3%1"'#*'2 *&('3)DD)+* 2''+D*R%D)+*'#*1A)*(-B)D* %#+*()$-B%1"'#D*'2 *1A)* ?OP 22
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
  24. 24. 92"1."#3+ " Q&/,0"("'1>)R+&."1,*+"()+0)(,1'')3+S Q&/,0"("'1>)R+&."1,*+"()+0)(,1'')3+S 1#&()"*)3O+,/()O+"33)3O+%/('1%1)3O+)#(1&2)3 " 0(/3$&'*+"()+/#.-+"../T)3+'/+4)"(+*$&2+ &."1,*+T2)#+'2)+31%%)()#&)+1#+ >1'",1#U,1#)(".+&/#')#'+1#+'21*+%//3+"#3+'2)+ ()%)()#&)+%//3+1*+"'+.)"*'+CIV+/% +'2)+92"1+ K:W " #/+,"X1,$,+",/$#'*+/% +,1&(/#$'(1)#'*+ '2"'+,"-+4)+"33)3+'/+%//3 F:=+92"1."#3+GCDDLJ@+?/'1%1&"'1/#+/% +'2)+!1#1*'(-+/%+ 8$4.1&+<)".'2+?/@CLH+U+HEACGCDDLJ+?$'(1'1/#+ Y"4)..1#5@+F//3+"#3+:($5+=3,1#1*'("'1/#+92"1."#3@+ 24
  25. 25. ! !"#$%&'()#*+,&$"-%.(/#)'"$( " &00"$"-%(-1 (.#2#)&,('"3)-%+$)"#%$.($-( &00"$"-%(-1 3-'/,#'#%$&)4(1--0.(&%0(56#&$(1,-+) 3-'/,#'#%$&)4(1--0.(&%0(56#&$(1,-+) " ")-%("%(1".6(.&+3#(&%0(2"$&'"%(7("%( ")-%("%(1".6(.&+3#(&%0(2"$&'"%(7("%( '&)*&)"%#(&%0(.+*&) '&)*&)"%#(&%0(.+*&) " '"%"'+'(&%0('&8"'+'(,#2#,.(&)#( "%"'+'(&%0('&8"'+'(,#2#,.(&)#( .$"/+,&$#0(1-)($6#.#(1-)$"1"3&$"-% .$"/+,&$#0(1-)($6#.#(1-)$"1"3&$"-% 9&-(:;(<(=+-%* 9&-(:;(<(=+-%* >:(?@AABCD(E,-F&,(7*)"3+,$+)#( G%1-)'&$"-%(H#$5-)I(?E7GHC(J#/-)$K(!"#$%&'(L7GJM( N-+%$)4(J#/-)$(7%%+&,(@AABD( 25
  26. 26. M+''&)4 ! ! ! ;-.$(3-+%$)"#.(6&2#("%0"2"0+&,()#*+,&$"-%.( ;-.$(3-+%$)"#.(6&2#("%0"2"0+&,()#*+,&$"-%.( /#)'"$$"%*(2-,+%$&)4(1-)$"1"3&$"-%(5"$6( 2&)"-+.(2"$&'"%.(&%0('"%#)&,. =-5#2#)O(3-%."0#)&F,#(0"11#)#%3#.("%($6#( =-5#2#)O(3-%."0#)&F,#(0"11#)#%3#.("%($6#( 3-%."0#)&F,#( &//)-&36($-5&)0.()#*+,&$"%*(2-,+%$&)4( &//)-&36($-5&)0.()#*+,&$"%*(2-,+%$&)4( &00"$"-%(-1 ('"3)-%+$)"#%$.("%($6#(P(3-+%$)"#. M"*%"1"3&%$(0"11#)#%3#.("%( M"*%"1"3&%$(0"11#)#%3#.("%( " 1--0(2#6"3,#(/#)'"$$#0 " 2"$&'"%.(&%0('"%#)&,.(&%0(1-)'.( /#)'"$$#0( " '"%"'+'(&'-+%$()#Q+")#0 " '&8"'+'(/#)'"$$#0 " %+$)"#%$(3-%$#%$R3-'/&)&$"2#(3,&"'.( /#)'"$$#0 26
  27. 27. !"#$%&'()*+,'&'$,+(- + .&/0&'()*+-()'1-12&'1(/ 27
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
  30. 30. 2&$,3)14+5,#%"'+*6 2&$,3)14+5,#%"'+*6 • "$$+%+&#)&- )#*%'+,#%6)%&)-&&$6 • #*%'+,#%).&#%,#%).4"+5 30
  31. 31. !"#$"%&'(&)*+",&)*--$..""&*/&01.2$.$*/&3/+& !"#$"%&'(&)*+",&)*--$..""&*/&01.2$.$*/&3/+& 4**+5&6*2&78"9$3:&;$".32(&<5"5&=))047;<>& $/$.$3."+&$/&?@@A ! B.&5."8&C&*6 &.D"&82*9"+12"E&+$59155"+&3.&FC.D &.D"&82*9"+12"E&+$59155"+& +$59155"+&3.&FC 5"55$*/&$/&;"9"-'"2&?@G? ! H*2I$/J&+*91-"/.&6*2&FC&7"55$*/&*6 &))047;< 6.8KLL6.8M63*M*2J 6.8M63*M*2JL9*+",L-"".$/J5L))047;<L99/65+1 6.8KLL6.8M63*M*2JL9*+",L-"".$/J5L))047;<L99/65+1 FCL/6FCN@A"M8+6 ! 31
  32. 32. 32
  33. 33. !"##$%&'(#)*&'&$+& ! ,-'.#-/0($'1"0()%2$'&-'3)&0-%)4'5"&6-#0&0$7' #$7.-%7084$'*-#'($/$4-.0%1'1"0($40%$7')%(' 4$1)4'&$+&7'*-#'&6$'#)&0-%)4')%('7)*$')((0&0-%' 4$1)4'&$+&7'*-#'&6$'#)&0-%)4')%('7)*$')((0&0-%' -* '$77$%&0)4'%"&#0$%&7'&-'*--(7 ! 977$%&0)4'%"&#0$%&7':$)%7')%;'7"87&)%2$' %-#:)44;'2-%7":$(')7')'2-%7&0&"$%&'-* '*--(<' %$$($('*-#'1#-=&6')%('($/$4-.:$%&')%(' '40*$<')%('=6026'2)%%-&'8$' :)0%&$%)%2$'-* '40*$<')%('=6026'2)%%-&'8$' 7;%&6$70>$('0%')($?")&$'):-"%&7'8;'&6$'8-(;' ! 5..402)84$'&-'8-&6':)%()&-#;')%('/-4"%&)#;' 5..402)84$'&-'8-&6':)%()&-#;')%('/-4"%&)#;' )((0&0-% -* '$77$%&0)4'%"&#0$%&7' ! @-#&0*02)&0-%':$)%7'&6$')((0&0-%'-* '-%$'-#' :-#$'$77$%&0)4'%"&#0$%&7'&-')'*--('A=6$&6$#'-#' %-&'0&'07'%-#:)44;'2-%&)0%$('0%'&6$'*--(B 33
  34. 34. !-%24"(0%1'#$:)#C7 34

×