Considerations in Developing a Functional
Food Product & Making it Good for a
Dr. R. B. Smarta
Interlink Marketing Consultancy Pvt. Ltd.
Health Foods & Dietary Supplements Association (HADSA)
11th April 2014
1. By Creating Uniqueness
Functional Foods are usually Customized for the
Intended Population to increase their life expectancy
through Food Technology.
2. By New Way in Researches
Mechanism of Action of
Human Clinical Trails
Research in new areas
that would aid in
Role of Biomarkers
To Establish Dose-
Analysis of Vehicles for
2.a. By Analyzing Vehicles for Bio-active
Food vehicle plays an important role in the overall
success of Functional Food via Consumer Compliance.
Few Roles of Vehicles (for Bioactive Ingredients):
Provide stable environment for the Bioactive Ingredients
Maintenance of bioavailability of Bioactive ingredients
Provide desirable sensory/organoleptic characteristics
By Analyzing Vehicles for Bio-active ingredients
Examples of Bioactive Vehicles (3/3)
Dairy products - milk beverages and yoghurt are widely used as
vehicles to deliver non-dairy bioactives, such as phytosterols or
omega-3 fatty acids.
Coffee - can be used both as a drink and to deliver the well-known
bioactive molecule caffeine & other Chlorogenic acids (CGAs).
Nanotechnology - Casein micelles may be useful as nanovehicles
for sensitive hydrophobic bioactives.
2.b. Role of Biomarkers (1/2)
In Functional Food Research, biomarkers are usually
biological endpoints that directly correlate with health
status or with exposure to specific health benefits.
They are a specific Physical Trait used to measure or
indicate the effects or progress of a disease or
Research in new areas such as Nutrigenomics,
Proteomics, Metabolomics, and other disciplines may
help identify the biological basis by which food
components promote health and wellness.
2.c. Research in new areas that would aid in
Nutrigenomics is research focusing on identifying and
understanding molecular-level interaction
between nutrients and other dietary bioactives with
Nutrigenomics complements the personalized medicine of the
Proteomics is the study of the full set of proteins encoded and
expressed by a genome, identification of proteins in the organism,
mapping their interactions and analyzing the proteins’ biologic
Its use in food technology is presented, especially for characterization
and standardization of raw materials, process development,
detection of batch-to-batch variations and quality control of the final
Metabonomics is the quantitative measurement of the dynamic
multiparametric metabolic response of living systems to
pathophysiological stimuli or genetic modification.
It is being used to assess the adequacy and safety of xenobiotics,
pharmaceutical agents, nutrients and functional
Bioinformatics is an interdisciplinary scientific field that develops
methods for storing, retrieving, organizing and analyzing biological
The metabolite and gene expression patterns discovered with
emerging bioinformatics tools may be used to monitor sequential
metabolic changes in response to dietary components/bioactive
components in functional foods, detection and characterization of
food allergens, facilitating evaluation of the safety and efficacy.
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