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Protein protein interaction basic

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this presentation include info for stater students and have basic knowledge of pro pro interaction

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Protein protein interaction basic

  1. 1.  Ayesha Aftab Malik Amber Malik
  2. 2.  Proteins are the workhorses that facilitate most biological processes in a cell.
  3. 3.  The majority of proteins interact with other proteins for proper function Publication of the human genome Development of the field of proteomics,
  4. 4. Two types Stable Transient Both types can be weak or strong
  5. 5.  Alter the kinetic properties of enzymes Allow for substrate channeling Create a new binding site Inactivate or destroy a protein Change the specificity of a protein for interaction with different proteins Serve a regulatory role
  6. 6. SlowTime consumingNot accurateDifficult to handleCostlyLack of equipments
  7. 7. Primary databasesInt actMintBindstringMeta databasesPINAAPIP
  8. 8.  STRING: known and predicted protein interactions. Interactions physical and functional associations The database currently covers 5214234 proteins from 1133 organisms.
  9. 9.  K VOTE to create seven different integrated networks by using values of k ranging from 1-7. modularity, similarity-based modularity, clustering score, enrichment.
  10. 10.  Proteins rarely act alone
  • KarishmaPatel98

    May. 17, 2018
  • MenakaMenakaramasamy

    Apr. 18, 2018
  • jayashanthi1974

    Aug. 2, 2017
  • suresh117

    Nov. 10, 2016
  • savicalista

    Dec. 9, 2015

this presentation include info for stater students and have basic knowledge of pro pro interaction

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