Statistics and epidemiology
For the membership examination
Ian Forde
Syllabus
• One variable, one population
• What’s the distribution?
• Normal and skewed distributions
• One variable, two p...
Measure of central tendency
• Mean: Sum of the values divided by their numbers
• Mode: Most frequently occurring value(s)
...
Measure of spread
• Variance: average squared
distance from the mean
• Standard division: Square
root of the variance
= √ ...
Haemoglobin concentration was measured
in a sample of dialysis patient and gave
following results (g/dL): 8.3, 11.3, 10.4,...
Which of the following statement
is true?
Which of the following statement is
true?
The mode can not be calculated for this sample
The Median can not be calculated ...
Epidemiology and Clinical trials
Ian Forde
Syllabus
• Study Design
• Accuracy, reliability and precision
• Sensitivity and specificity
• Risk
• Prevention
• Bias
• I...
Exposure Outcome
COHORT STUDIES
• Prospective
• Best of rare exposure, common
outcome
• Allow us to look at many
outcomes ...
Which would be the study designs
would best be suited for the
situation described below?
Which would be the study designs would best
be suited for the situation described below?
A. A case control study to look a...
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Medical Statictics and Epidemiology - MRCP 1 - 123Doc Education

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Medical Statictics and Epidemiology, as part of the MRCP 1 course. These are slideshows only. The demonstration with video presentation and explanation that goes along with these slides, as well as free example exam questions and the paid full e-lecture can be viewed at https://www.123doc.com/electures/statistics-and-epidemiology/

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Medical Statictics and Epidemiology - MRCP 1 - 123Doc Education

  1. 1. Statistics and epidemiology For the membership examination Ian Forde
  2. 2. Syllabus • One variable, one population • What’s the distribution? • Normal and skewed distributions • One variable, two populations • Is the difference real or due to chance? • Hypothesis testing, errors and p-value • Two variables, one population • Are they correlated?
  3. 3. Measure of central tendency • Mean: Sum of the values divided by their numbers • Mode: Most frequently occurring value(s) • Median: the middle value when arranged in order of size
  4. 4. Measure of spread • Variance: average squared distance from the mean • Standard division: Square root of the variance = √ Variance Interquartile range: the middle 50 % of the values when arranged in order of size _ 2 Variance = ∑ (x-x) n is the standard way of representing the arithmetic mean pronounced x bar ∑ is the Greek capital latter sigma that means total of or sum of X is the value of the variable ‘x’ N is the number of the volume or data points
  5. 5. Haemoglobin concentration was measured in a sample of dialysis patient and gave following results (g/dL): 8.3, 11.3, 10.4, 12.1, 9.6, 8.3
  6. 6. Which of the following statement is true?
  7. 7. Which of the following statement is true? The mode can not be calculated for this sample The Median can not be calculated for this sample The mean and the median in this sample have the same value The mode and the median in this sample have the same value If the sample were normally distributed we would expect the mode, the median and the mean to have different value
  8. 8. Epidemiology and Clinical trials Ian Forde
  9. 9. Syllabus • Study Design • Accuracy, reliability and precision • Sensitivity and specificity • Risk • Prevention • Bias • Intention to treat analyses
  10. 10. Exposure Outcome COHORT STUDIES • Prospective • Best of rare exposure, common outcome • Allow us to look at many outcomes simultaneously CASE CONTROL STUDIES • Retrospective • Best of rare outcome, common exposure • Allow us to look at many exposure simultaneously • Susceptible to bias
  11. 11. Which would be the study designs would best be suited for the situation described below?
  12. 12. Which would be the study designs would best be suited for the situation described below? A. A case control study to look at the relationship between brain tumors and mobile phone use B. A case control study to look at the relationship between skin cancer and space flight C. A cohort study to look at the relationship between pure red cell aplasia and air travel D. A randomized control trail to look at the relationship between melanoma and sun block use E. A randomized control trail to look at the relationship between childhood television watching and amblyopia

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