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ReaMetrix Hiv Reagent Portfolio
 

ReaMetrix Hiv Reagent Portfolio

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ReaMetrix HIV Reagents

ReaMetrix HIV Reagents

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    ReaMetrix Hiv Reagent Portfolio ReaMetrix Hiv Reagent Portfolio Presentation Transcript

    • Management of HIV Infection in Resource Poor Settings Accurate & Affordable Reagent Alternatives
    • HIV in India – Current Status
      • HIV Prevalence rate in India 0.36%
        • 2.5 Million HIV Infections
      • By year 2010, estimates indicate that there will be between 8-15 million HIV infected individuals
      • Management of HIV Infection
        • Providing Anti Retroviral therapy (ART)
        • Immunophenotyping
          • CD4 T-Lymphocyte Count
        • Viral Load Assay –
          • PCR – quantitate virus levels in blood
      CD4 counts are the single most important criteria to guide clinical decision-making on when to use ART
    • ReaMetrix Solutions for CD4 Enumeration
      • Dry-Tri T-STAT CD348
      • 3 color single tube reagent for open flow Cytometers
      • eg. BD FACScan ™, BD FACSCalibur ™, BC EPICS XL™)
      • Dry-Tri T-STAT CD3445
      • 3 color single tube reagent for open flow Cytometers
      • (eg. BD FACScan™, BD FACSCalibur™, BC EPICS XL™)
      • ReaPan 34845
      • 4 color single tube reagent for open Flow Cytometers
      • (eg. BD FACSCalibur™)
      • Rea T count
      • 2 color dual tube reagent for FACScount ™ Platform
      • ReaPan 34G-38G
      • 2 Color dual tube reagent for the Guava™ Platform
    • ReaMetrix Assay Reagent Characteristics
      • Methodology
      • Absolute CD4 testing by flow Cytometry – gold standard method
      • Employ simple Lyse/no wash protocol - single platform technology
      • Convenience
      • Provided as a ready to use format. No additional dispensing
      • Unitized form
      • Pre-dispensed reagents in unitized form – reduces pipetting errors
      • Stability & storage
      • Dried down reagents – do not require cold storage. No aggregation of
      • antibodies & beads in dried form
      • Simplified work flow
      • Minimal hand on time - just require sample pipetting, reduced steps
    • ReaMetrix Assay Reagent Characteristics
      • Accurate & reproducible
      • Workshop approved antibody clones – provide excellent Analytical
      • Specificity & Analytical Sensitivity
      • Extensively validated reagents in various private & public labs in India
      • Sample stability
      • Processed samples can be stored for up to
      • 7 days prior to analysis ( CV = 5.7% ).
      • Affordable
      • All of these attributes without compromising affordability
      • Technical support
      • ReaMetrix provides training on Cytometer and reagent
      • ReaMetrix provides technical support online & through personal visits
    • Dry-Tri T-STAT CD348
      • 3 color single tube reagent
        • Anti CD4 – Atto488* (FITC eq. dye)
        • Anti CD8 – R-PE
        • Anti CD3 – R-PE-Dy649* (Cy5 eq. dye)
      • Provides absolute counts (Cells/µL) of CD3+, CD4+, CD8+ Cells & CD4/CD8 Ratio
      • Validated with commercial reagents at NARI, YRG Care
      • CE Marked reagent
      Reagents are suitable to run on open flow cytometers such as BD FACScan, BD FACSCalibur, Beckman Coulter EPICS-XL etc. Reagents supplied in Dry, Unitized Format * Dyes qualified by ReaMetrix to assure superior performance
    • Dry-Tri T-STAT CD3445
      • 3 color single tube reagent
        • Anti CD4 – Atto488* (FITC eq. dye)
        • Anti CD3 – R-PE-Dy649* (Cy5 eq. dye)
        • Anti CD45 – R-PE
      • Provides a bsolute counts (Cells/µL) of Absolute Lymphocyte Count (ALC), CD3+, CD4+, % CD4 Counts
      • Validated with commercial reagents at leading path labs in India
      • Suited for aged blood samples
      Reagents are suitable to run on open flow cytometers such as BD FACScan, BD FACSCalibur, Beckman Coulter EPICS-XL etc. Reagents supplied in Dry, Unitized Format * Dyes qualified by ReaMetrix to assure superior performance
    • ReaPan 34845
      • 4 color single tube reagent,
        • Anti CD4 – APC
        • Anti CD8 – R-PE
        • Anti CD3 – Atto488* (FITC eq. dye)
        • Anti CD45 – PerCP
      • Provides a bsolute counts (Cells/µL) of ALC, CD3+, CD4+, CD8+ Cells, % CD4 & CD4/CD8 Ratio
      • Validated with BD multiTEST 4 color reagent at leading path. Lab in India.
      • Suited for aged blood samples
      • Designed for BD FACSCalibur dual laser flow Cytometer
      • CE marked
      Reagents supplied in Dry, Unitized Format * Dyes qualified by ReaMetrix to assure superior performance
    • Rea T-Count Reagent
      • Rea T-count CD3/CD4 & CD3/CD8 re agent
        • Designed for BD FACSCount flow Cytometer
        • Available as 2 color dual tube reagent for
          • CD3+, CD4+, CD8+, CD4/CD8 ratio estimation
        • Available as 2 color single tube reagent for
          • CD3+, CD4+ estimation
        • Alternative for FACSCount reagent
        • Reagent validated at
          • National HIV Immunology laboratory, Canada
          • Zimbabwe
      Reagents supplied in Dry, Unitized Format
    • ReaPan Reagents for the Guava Platform
      • ReaPan 34G
        • 2 color single tube reagent
        • Provides absolute counts (Cells/µL) of CD3+, CD3+CD4+ counts
      • ReaPan 34G & 38G
        • 2 color single dual reagent
        • Provides absolute counts (Cells/µL) of CD3+, CD3+CD4+ & CD3+CD8+ counts
      • Validated with Guava Reagent at KIMS, Bangalore
      Reagents supplied in dry, unitized format
    • Summary…
      • ReaMetrix supplies all reagents with ReaLyse, a buffer for lysing and fixing samples or ReaFix, a buffer for fixing samples after staining
      • ReaMetrix has the capability to develop CD4+ enumeration solutions for any flow cytometer platform.
      • ReaMetrix can customize solutions as per your need.
      • Work is in progress for reagent development for other platforms.
    • Manufactured by ReaMetrix India Pvt. Ltd. 50-B, II Phase, Peenya Industrial Area Peenya, Bangalore 560058, India Ph: +91-80-28378693/5, Fax: +91-80-41172451 E-mail: info@reametrix.com www.reametrix.com Further details: