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Zahoormir

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  • 1. Title; nano materials to create a new delivery system that promises to solve thechallenge of the poor water solubility of todays most promising anti cancer drugs andthere by increase their effectiveness..The title of my project which I above mentioned.in this project we are going to evaluatethe nanoparticles for the use of cancer treatment and make nano particles modified battaching a ligand against a cancer cell specific receptor can make the nano particlesrecognizable by cancer cells. In common anticancer drugs which are poorly water soluble[e.g;cpt or taxol}must bemixed with solvents and delivered into the body. But these elements produce toxic sideveffects and infact decrease the potency of the cancer therapy,to over come these problemsdrug delivery system using pegylated polymers, liposomal particles or albumin basednanoparticles have been developed.Silica nano particles show promise for delivering compothecin and other water insolubledrugs.The beauty of my project is that these nanoparticles are biocompatiblecontain tubularpores and are relatively easy to modify.Refrencce:research of ULCAs California nano systems institute and Johnson cancercenter report a novel approach using silica based nanoparticles to deliver the anti cancerdrug{camptothecin} into human cance cells…study is led by fuju tamanoi,ULCA professor of microbiology, immunology andmolecular genetics and director of the Johnson cancer center signal transduction andtherapeutics,program area and Jeffrey zink, ULCA professor of chemistry andbiochemistry…

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