Platelets are blood cells that help control bleeding. When a blood vessel is damaged, platelets collect at the site of injury and temporarily repair the tear. They then activate substances in plasma which form a clot and allow the wound to heal.
Result in destruction of a large proportion of the patient's platelets and may render the remaining viable platelets to be dysfunctional. The indications for transfusion in such patients is controversial.
The most common of these is aspirin, and its similar drug class, the NSAIDs. Other antiplatelet drugs are commonly prescribed for patients with acute coronary syndromes.When surgery is undertaken following the administration of these drugs, bleeding can be serious.
An unconfirmed, but helpful, way to determine whether a patient is recovering from chemotherapy-induced thrombocytopenia is to measure "reticulated" platelets, or young RNA-containing platelets, which signifies that the patient is starting to make new platelets.