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Student generated Drug Presentation

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    • 1. Lysergic Acid Diethylamide
    • 2. Introduction to LSD• Hallucinogen• Potent mood-changing chemical• 20-80 micrograms of LSD per dose• Odorless, colorless, bitter taste• Usually taken by mouth• Tablets, capsules, liquid form, blotter paper• Given through intramuscular or intravenous injection (liquid)
    • 3. Dependence/Tolerance• LSD is not a highly addictive drug• Does produce cravings associated with physical addiction• People stop on their own• May become tolerant, up doses• Does not cause physical withdrawal symptoms
    • 4. Short-Term Effects• Hallucinations, general the user knows they are unreal• Distorted perception of depth, time, and size of objects• Synesthesia (hearing colors, seeing sounds)• Heightened senses• Works similarly to serotonin (mood,sleep,appetite)
    • 5. Short-Term Physical Effects
    • 6. Long Term Effects• No controlled studies• "Flashbacks" or visual hallucinations from past acid trips• Prolonged psychotic states• Deaths- overdose, suicides, accidental, murders• Prolonged anxiety and depression after use of the drug is stopped• Hallucinogen persisting perception disorder (HPPD) severe disorder which consists of constant flashbacks
    • 7. Potency/Type• LSD is a hallucinogen• Drug that causes profound distortions in a persons perception of reality• Very potent• One of the most potent mood-changing chemicals• Manufactured from lysergic acid, which is found in fungus that grows on certain grains• Threshold dose 20ug• Common 50-150ug• Lethal Overdose 12,000 ug
    • 8. Neuroscience of LSD• Unpredictable• Interferes with the brains serotonin receptors- inhibit neuro transmission, stimulate it, or both• Affects the way the retinas process information and the conduction of that info to the brain
    • 9. Antagonist or Agonist?• Both• Antagonist: blocks the receptors, preventing serotonin from having its normal effects• Agonist: LSD causes the same effects as serotonin therefore LSD acts a s a neurotransmitter because it has same properties as serotonin
    • 10. Bibliography http://science.howstuffworks.com/lsd4.htm

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