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Short case...Neurofibromatosis type 2
Short case...Neurofibromatosis type 2
Short case...Neurofibromatosis type 2
Short case...Neurofibromatosis type 2
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Short case...Neurofibromatosis type 2


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Short case...Neurofibromatosis type 2

Short case...Neurofibromatosis type 2

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  • 1. Short case publication... version 1.19 | Edited by professor Yasser Metwally | April 2008 Short case Edited by Professor Yasser Metwally Professor of neurology Ain Shams university school of medicine Cairo, Egypt Visit my web site at: A 22 years old male patient presented clinically with bilateral tinnitus, headache, bilateral diminution of hearing, bilateral papilledema, bilateral facial nerve palsy, bulbar cranial nerves dysfunction, right sided cerebellar manifestation and bilateral long tract dysfunction. DIAGNOSIS: NEUROFIBROMATOSIS TYPE 2
  • 2. Figure 1. Bilateral vestibular schwannomas. The bilateral cerebellopontine angle tumors are hypointense on the precontrast MRI T1 images (Antoni B schwannomas). Notice that the brain stem is bilaterally compressed and squeezed by the bilateral tumors. Also notice the CSF cleft that separates the bilateral tumors from the neural tissues (The tumors are extra-axial). Moderate degree of hydrocephalus is present. Figure 2. Bilateral vestibular schwannomas. Postcontrast MRI T1 images showing dense and uniform contrast enhancement of the bilateral tumors.
  • 3. Figure 3. Bilateral vestibular schwannomas. MRI T2 and FLAIR images. The tumors have heterogenous signal on both T2 and FLAIR images with hyperintense zones which, most probably, represent cystic (fluid -filled) areas (Antoni B tissues). Figure 4. Bilateral vestibular schwannomas. MRI FLAIR images. Notice the moderate hydrocephalic changes and the transependymal edema. Also notice the CSF cleft that separates the tumor from the brain stem. The tumor hyperintensity is due to the existence of cystic changes (Antoni B tissues).
  • 4. Addendum A new version of short case is uploaded in my web site every week (every Saturday and remains available till Friday.) To download the current version follow the link quot;;. You can download the long case version of this short case during the same week from: or visit web site: To download the software version of the publication (crow.exe) follow the link: At the end of each year, all the publications are compiled on a single CD-ROM, please contact the author to know more details. Screen resolution is better set at 1024*768 pixel screen area for optimum display For an archive of the previously reported cases go to, then under pages in the right panel, scroll down and click on the text entry quot;downloadable short cases in PDF formatquot; References 1. Metwally, MYM: Textbook of neurimaging, A CD-ROM publication, (Metwally, MYM editor) WEB-CD agency for electronic publishing, version 9.1a January 2008