RSC 325: Clinical Pathophysiology                        SYLLABUS                   Summer Semester 2012               Cou...
Massachusetts College of Pharmacy and Health Sciences                School of Radiologic Sciences                        ...
Course objectives:Upon completion of the course the student will be able to:1. Describe the pathophysiology for selected h...
Case StudiesStudents will respond to the case studies related to the online content of this course.For each of the case st...
The MCPHS School of Radiologic Sciences practice is to eliminate decimal points and toassign whole numbers as final course...
*Please email course faculty via accounts and not via Additionally, please allow 24-48...
classroom learning experiences directly correlates with successful course completion andrepresents a basic professional be...
RSC 325: Clinical Pathophysiology                                    Course Outline   Date                       Course Co...
Week 4      ONLINE SESSION (NOT in Class)                                  Gould/WB ChaptersThursday     Thromboembolic D...
o   Gallbladder disorders              o   Jaundice              o   Hepatitis              o   Cirrhosis              o  ...
Week 9      Quiz 4 Online Due (Content of Weeks 7 and 8)   Gould/WB Chapters 26Thursday     Disorders of the musculoskele...
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  1. 1. RSC 325: Clinical Pathophysiology SYLLABUS Summer Semester 2012 Course Coordinator and Faculty Dr. Mahmoud Kaddoura, PhD, CAGS, MSN, MEDRSC 325 1Summer 2012
  2. 2. Massachusetts College of Pharmacy and Health Sciences School of Radiologic Sciences RSC 325 Clinical Pathophysiology Summer 2012 4 CreditsCourse Coordinator and FacultyMahmoud Kaddoura PhD, CAGS, MSN, MEDOffice Hours: Mondaya and Thursdays 10:30 a.m. – 12 NoonGriffin 304Phone: 617-274-3381Email: Mahmoud.kaddoura@mcphs.eduCourse MeetingsDay/Time: Mondays and Thursdays 8 a.m. – 10:30 a.m. and as designated by faculty,OnlineLocation: Fennel, Room 113Campus: BostonCourse Description:Students build on prerequisite biological sciences courses and gain foundationalknowledge regarding normal and abnormal pathophysiological principles. Students learnthe etiology, pathogenesis and clinical manifestations of selected health problems acrossthe lifespan in diverse populations. Students explore current research findings relevant tothe pathophysiology of common illnesses. Students analyze laboratory data in light ofactual and potential pathophysiological processes. Special emphasis is given to the casestudy analysis of pathophysiological manifestations and related complications ofcommon health problems.RSC 325 2Summer 2012
  3. 3. Course objectives:Upon completion of the course the student will be able to:1. Describe the pathophysiology for selected health problems across the lifespan.2. Explain the developmental physiology, usual etiologies, pathogenesis, and clinical manifestations of commonly seen altered health states.3. Describe the genetic relationship, cultural and ethnic considerations of relevant health problems across the lifespan.4. Analyze the relationship between normal physiology and pathological phenomena produced by altered states across the life span.5. Explain the complications associated with selected health problems.6. Analyze evidence-based research literature and use it to explain the diagnosis, mechanisms of signs and symptoms, and treatment of selected case studies.Required texts and materials:Required:Gould, B. & Dyer, R. (2012). Pathophysiology for the Health Professions (4th ed.). St. Louis, MO: Saunders/Elsevier. ISBN-13: 978-1-4377-0965-0.Recommended:Gould, B. & Dyer, R. (2012). Study Guide for Pathophysiology for the HealthProfessions (4th ed.). St. Louis, MO: Saunders/Elsevier. ISBN-13: 978-1-4377-1456-2.Methods of Instruction:Methods of instruction for the course may include, lecture, on-line content, use oftechnology and media, guest speakers, discussion, weekly assignments, and case studies.Learning in the course will be enhanced by the use of Blackboard technology.Methods of Evaluation:1. Quizzes (4 total- 12.5% each) 50%2. Case Studies 20%3. Comprehensive Final Examination 20%4. Pop quizzes, prompt attendance and active participation 10% 100%QuizzesThere will be five quizzes that will measure student progress on a sequential basis duringthe course. Questions on the quizzes will be derived from the content of the course priorto each quiz, including questions from the text book, online content, power point slides,and/or other appropriate resources. The quizzes are not cumulative and will include onlythe content not tested on prior to each quiz. Some of the quizzes will be taken in class andsome others will be taken online, according to the discretion of the course faculty.RSC 325 3Summer 2012
  4. 4. Case StudiesStudents will respond to the case studies related to the online content of this course.For each of the case studies, students are required to read the assigned readings andrelated evidence-based research literature first, and then analyze the cases to answer theopen-ended questions related to the diagnosis, pathophysiology of signs and symptoms,and treatment of the clients in the selected case studies. The answers to each case studyshould be concise (less than one page per case using any format). Completed responsesshould be posted in the Case Studies Forum on blackboard and a hardcopy should behanded to the professor on or before the due deadline. Though this is not a group project,please take the opportunity to read other responses and feel free to add comments anddiscuss why you agree or disagree with the postings of your peers based on evidence-based practice and research. Please complete your answer to each case study within onepage, single spaced, and using 12 point font.Final ExaminationThe comprehensive final examination will measure students‟ understanding of the entirecontent covered throughout the course. Questions on the comprehensive final exam willbe derived from all sources of learning materials utilized in the course to include the textbook, online content, power point slides, and/or other appropriate resources.Pop quizzes, prompt attendance and active participationStudents are expected to have a pop quiz any time the professor decides, at the beginningof any session he chooses. The questions of the pop quizzes are derived from the assignedreadings for the day of the pop quiz. Students are required to attend all classes andparticipate actively in the discussion of each session to foster their active learning.Although the pop quizzes, prompt attendance, and active participation are allotted 10% ofthe final grade, the course coordinator and faculty reserves the right to add up to 10% tothe grade of those students who always show up to class on time and come very wellprepared, participate actively in the classroom discussion, perform excellently in the popquizzes, and reflect their adequate preparation and understanding of the content in class.Grading Criteria:A 4.0 100-94A- 3.7 93-90B+ 3.3 89-87B 3.0 86-83B- 2.7 82-80C+ 2.3 79-78C 2.0 77-73 (minimum passing grade is 75%)C- 1.7 72-70D 1.0 69-60F 0.0 <60RSC 325 4Summer 2012
  5. 5. The MCPHS School of Radiologic Sciences practice is to eliminate decimal points and toassign whole numbers as final course grades. The "rounding up” of a final grade is basedon 0.50 or above, not 0.49, 0.48, etc. For example, if the student grade is 72.49 or less,his/her final grade of record is 72. On the other hand, if the student grade is 72.50 orabove, then his/her final grade of record is 73.Course Requirements: It is the responsibility of the student to complete all readingassignments prior to lecture and lab. All students are expected to be punctual for everyclass and very well prepared to take a pop quiz at the beginning of each in class session.Cell phones or any other electronic device are not to be used in the lecture hall. Anystudent using one of these devices will be asked to leave the class immediately. Pleasenote; A ringing phone means you are using it. So turn phones off when you come toclass. Failure to comply will result in the student being asked to leave the class.Assessment of Student Learning and Teaching EffectivenessStudents will be asked to provide regular class evaluations via „minute paper‟ submission(anonymous) and through Socratic dialogue. In addition, students will participate incomputerized end of course evaluations (confidential).Students with DisabilitiesStudents with documented disabilities who wish to request reasonable accommodationsunder section 504 of the Rehabilitation Act and the Americans with Disabilities Actshould contact the Coordinator of Disability Support Services in the Academic Supportservices office (Boston Campus 617-732-2755) to discuss the accommodations process.PlagiarismStudents are expected to abide by the College‟s Academic Honesty Policy as explained inthe MCPHS Student Handbook. Plagiarism is considered a violation of this policy.Plagiarism is defined as submitting another person‟s work as one‟s own without properacknowledgment or using the words or ideas of others without crediting the source ofthose words or ideas.E-mail:All MCPHS students are required to open, utilize, and maintain (i.e. keep storage withinthe maximum set by IS) an MCPHS e-mail account. All students are responsible forregularly checking their MCPHS e-mail and for the information contained therein. Pleasecheck and empty your email accounts regularly, if your email account is full you will notreceive email sent by the instructor. Only MCPHS accounts will be used in all mattersrelated to academics, student life, and College notifications. The College does notforward MCPHS e-mail to personal e-mail accounts.*Please check and empty your email accounts regularly, if your email account is full youwill not receive email sent by the professor. This will not be considered an adequateexcuse for not completing assignments.RSC 325 5Summer 2012
  6. 6. *Please email course faculty via accounts and not via Additionally, please allow 24-48 hours for faculty response.Quiz/Exam ReviewsAll students will have the opportunity to review exams. This process is used to helpstudents determine how to improve the way they prepare for and take tests. After theexam is taken and the grade is posted by the respective faculty member, there will be adesignated time to allow students to review the exam. If the student has any questions orconcerns regarding the exam they should meet with respective faculty during postedoffice hours or by appointment. Once the review has taken place, students will haveno further access to their quizzes/exams for security reasons.Attendance and Absences from ExaminationsRegular class attendance is mandatory. Absences of more than six (6) didactic hourswill result in a final grade reduction of one full letter grade (e.g. B to C). Absences ofmore than nine (9) didactic hours will result in a failing grade for the course.In the case of illness or prolonged absence, it is the student‟s responsibility to notify theoffice of Academic Support Services (Boston) and his/her course faculty within 24-48hours from the first date of absence. With acceptable documentation from a student, anofficial memorandum will be issued notifying faculty of an excused absence. In the caseof an approved, excused absence, the course faculty will make reasonable attempts toassist the student to satisfy requirements of the course (e.g., make up exams).Students are expected to abide by instructions in each course syllabus regarding studentresponsibilities related to class absences. Students who fail to do so may be ineligible toreceive an excused absence, regardless of the reason for the absence. With respect tocompletion of work missed, if an acceptable agreement between the student and professorcannot be reached, the School Dean will serve as arbitrator (reference MCPHS Catalog2009-2012, p.71). The faculty has the right whether or not to allow make up tests.Late Papers (Case Studies)Students may only make up missed class assignments, quizzes, and exams if an “excusedabsence” has been granted and if the faculty approves. Graded work that is missed due toan “unexcused absence” will be assigned a grade of ZERO. Students are expected tosubmit all papers on the dates listed in the syllabus unless an extension has been grantedby course faculty. Late papers will be marked down by 5 points for each late day,including weekends and holidays. Issues/concerns regarding the completion and orsubmission of the assignment must be brought to the attention of the course faculty priorto the due date of the assignment. Grades will not be re-considered after submission ofthe assignment and subsequent posting of the grade.Attendance PolicyMCPHS supports a learner-centered environment. Attendance and participation inRSC 325 6Summer 2012
  7. 7. classroom learning experiences directly correlates with successful course completion andrepresents a basic professional behavior. Therefore, students are responsible to come toclass on time prepared, and engage in their own learning and professional comportment. Students are expected to attend all classes. Regardless of whether they attend all classes or not, students are responsible for all class content and assignments. Under no circumstances may lectures be recorded. Students may only make up missed class assignments, quizzes, and exams if an excused absence has been granted and if the faculty approves a makeup. Graded work that is missed due to an unexcused absence will be assigned a grade of “0”. The course faculty/school administrative assistant must be notified of an absence as soon as possible the morning of the day of the absence. If reasons prevent the student from providing prior notice, the students must inform the appropriate Dean and responsible faculty member/ administrative assistant of the absence as soon as possible, not after 3:00 pm of the same day.PunctualityPunctuality is expected of students for all classes. Neither tardiness nor leaving earlywill be tolerated, as it impacts adversely upon the student‟s learning experience and isdisruptive to fellow students and faculty. The faculty has adopted a standard practice tominimize disruption to the classroom learning environment by closing the classroom atthe start of the class session. Students who arrive to a class session after the door is closedmust wait to enter the classroom at the first break. Students will be held accountable forall missed material.Other policies pertaining to punctuality are as follows: Students who are late to class without an approved excused absence may be denied the opportunity to take a scheduled examination, quiz, or pop quiz at the faculty‟s discretion. Students with an excused absence, tardiness, or early departure are expected to complete the required work and obtain handouts, etc., from classmates, and are responsible for learning the missed material. Students are expected to stay for the entire duration of the class. If a student must leave early, it is expected that the student will present an approved excused reason for leaving early (approved by the appropriate Dean/Assistant Dean in advance). If a student leaves early without a prior excused reason for doing so, the final course grade will be dropped by ½ letter grade. More than one unexcused early departure may result in failure of the course.Disclaimer: Please note that this syllabus is not a contract. The course coordinator and faculty (Dr.Kaddoura) will make every possible attempt to abide by the information and policies/guidelines contained within this syllabus. In the event of a change to anything in thisdocument, students will be given advanced notice.RSC 325 7Summer 2012
  8. 8. RSC 325: Clinical Pathophysiology Course Outline Date Course Content Assigned ReadingWeek 1  Review of Syllabus and Course Requirements Gould/WB Chapter 1, 7, 12Monday14 May  Introduction to Pathophysiology o Cellular Structure and Function o Cellular responses to stress, injury and aging o Cell Proliferation and tissue regeneration and repair o Genetic control of cellular functionWeek 1  Disorders of Fluid and Electrolytes Gould/WB Chapter 6Thursday  Disorders of Nutrition17 MayWeek 2  Immune Disorders Gould/WB Chapter 3Monday o Hypersensitivity disorders21 May o Autoimmune diseases o Immunodeficiency disordersWeek 2  Pathophysiology of Inflammation , Inflammatory Gould/WB Chapters 2,4Thursday Response and fever24 May  Infection o Infectious Diseases o New and emerging infectious diseasesWeek 3 ONLINE SESSION (NOT in Class) MEMORIAL DAYMonday  Cancer and Oncology Disorders28 MayWeek 3 Quiz 1 Online Due (Content of Weeks 1 and 2)Thursday ONLINE SESSION (NOT in Class)31 May  Various Types of CancersWeek 4  Disorders of Hematology System Gould/WB Chapters 5,17Monday o Hematological system overview4 June o Disorders of red blood cells  Anemias  Polycythemia Vera  Age-related changes to RBC‟s o Disorders of white blood cells  Neutropenia o Neoplastic Disorders  Leukemias  Malignant lymphomas  Plasma Cell Dyscrasias RSC 325 8 Summer 2012
  9. 9. Week 4 ONLINE SESSION (NOT in Class) Gould/WB ChaptersThursday  Thromboembolic Disorders 17,18,19 (focus reading on7 June o Coagulopathies assigned topics) o Bleeding disorders o Coagulation disorders o DICWeek 5 Case Studies Due in Class Gould/WB Chapter 18Monday  Cardiovascular Disorders11 June o Acute Coronary Syndromes o Hypertension o Lipid Disorders o Heart Failure o Conduction disorders o ShockWeek 5 Quiz 2 Online Due (Content of Weeks 3 and 4) Gould/WB Chapter 13Thursday ONLINE SESSION (NOT in Class)14 June  Pain o Headache o Acute Pain o Chronic PainWeek 6  Diseases of the Respiratory System Gould/WB Chapter 19Monday o Asthma18 June o Chronic Obstructive Airway Disorders  Emphysema  Chronic Bronchitis o Respiratory Tract Infections  Pneumonia  Common Cold  Cystic Fibrosis  TuberculosisWeek 6  Diseases of Renal Function Gould/WB Chapter 21Thursday o Urinary Tract Infections21 June o Urolithiasis o Nephrosclerosis o Polycystic Kidney Disease o Renal Failure (Acute and Chronic)Week 7  Disorders of the Gastrointestinal tract, liver and biliary Gould/WB Chapter 20Monday system25 June o Hiatal Hernia o Gastroesophageal Reflux disease o Gastritis o Peptic Ulcer Disease o Dumping Syndrome RSC 325 9 Summer 2012
  10. 10. o Gallbladder disorders o Jaundice o Hepatitis o Cirrhosis o Acute Pancreatitis o Chronic Inflammatory Bowel Disorders o Appendicitis o Diverticular DiseaseWeek 7 Quiz 3 Online Due (Content of Weeks 5 and 6) Gould WB Chapters 22,23Thursday  Diseases of the Nervous System26 June o Review of the nervous system, structure and function o Disorders of neuromuscular function  ALS  MS  Myasthenia Gravis o Disorders of brain function  Stroke  Seizures  Parkinson‟s Disease  Alzheimer‟s DiseaseWeek 8  Diseases of Sensory Function Gould/WB Chapter 24Monday o Disorders of Eye2 July  Glaucoma  Cataracts  Macular degeneration o Disorders of the Ear  Hearing loss  Ear infectionsWeek 8 ONLINE SESSION (NOT in Class) INDEPENDENCE Gould/WB Chapters 21Thursday  Genitourinary and Reproduction5 July o Male genitourinary system o Disorders of the male genitourinary system o The female reproductive system o Disorders of the female reproductive system  Sexually transmitted infectionsWeek 9  Diseases of Endocrine Glands Gould/WB Chapter 25Monday o Pituitary and Growth Disorders9 July o Thyroid Disorders o Disorders of Adrenal Cortical Function  Diseases of the Pancreas o Diabetes Mellitus RSC 325 10 Summer 2012
  11. 11. Week 9 Quiz 4 Online Due (Content of Weeks 7 and 8) Gould/WB Chapters 26Thursday  Disorders of the musculoskeletal system12 July o Osteoporosis o Osteomalacia o Paget‟s Disease o Osteoarthritis o Rheumatoid Arthritis o Fibromyalgia o Multiple Sclerosis o GoutWeek 10  Diseases of the Skin Gould/WB Chapter 27Monday o Contact dermatitis16 July o Urticaria o Eczema o Psoriasis o Scleroderma o Skin CancersWeek 10 Final Exam ReviewThursday19 JulyWeek 11 Comprehensive Final ExamMonday All the Best and God Bless23 July RSC 325 11 Summer 2012