TYPO3 4.6 takes the opportunity to introduce new requirements and cleaning code from old, deprecated, options. This is made possible thanks to the 4.5 release which will be supported until 2014.
MS Internet Explorer 6 support has been dropped for the backend. So are older versions of GraphicsMagick and ImageMagick and PHP 5.3 is now a requirement.
But TYPO3 4.6 will be much more than a trimmed-down version of 4.5 as it includes a completely reworked localization handling based on XLIFF and Pootle that shall be used by the v5 as well.
In short, this talk is about presentating the changes, the new features and how to use them.