0
Holoprosencephaly

{

Living with HoPE
HPE


Birth defect which occurs during the first
few weeks of gestation.



Brain does not divide into separate
hemisphe...
HPE


Affects between 1 in 5,000-10,000 live births



Frequency may be as high as 1 in 200-250



< 3% of all fetuses...
HPE


Cause Unknown



Chromosomal abnormalities identified in some
patients



X-linked recessive in some families
HPE risk factors


Maternal diabetes



Drugs during pregnancy







Aspirin
Lithium
Anticonvulsants

Infections du...
HPE
Alobar
No Division
 Semilobar
Partial Division
 Lobar
Divided with areas of fusion
 MIV (middle interhemispheric va...
HPE symptoms


Excessive fluid in the brain



Varying degrees of mental retardation



Epilepsy



Other organ system...
HPE physical characteristics


Primarily Facial Deformities






Small head
Single-nostril nose
Close set eyes
Clef...



Control with medication
Telling other students what to expect




Unexpected seizures can be scary for everyone

Wh...


Tube feeding can be given in 3 different ways






Tube positioning








Pump
Gravity drip
Syringe
Jejunos...


Depending on degree of delay students may
experience difficulty with









Learning
Communication
Social & In...






Physical
Language and speech
Social and emotional
Adaptive
Cognitive

Early Intervention







Developmental teachers
Occupational therapists
Physical therapists
Speech and language pathologist/audiologis...


“In its simplest terms, occupational therapists and
occupational therapy assistants help people across
the lifespan par...


“Physical therapists can teach patients how to
prevent or manage their condition so that they
will achieve long-term he...
http://familiesforhope.org



The Carter Centers for Brain Research in Holoprosencephaly & Related
Malformations


http:...
Cognitive
http://www.nsnet.org/start/cognitive.pdf
Early Intervention
http://www.earlyinterventionsupport.com/therapyoptio...
Upcoming SlideShare
Loading in...5
×

Holoprosencephaly

665

Published on

Published in: Health & Medicine
0 Comments
1 Like
Statistics
Notes
  • Be the first to comment

No Downloads
Views
Total Views
665
On Slideshare
0
From Embeds
0
Number of Embeds
2
Actions
Shares
0
Downloads
27
Comments
0
Likes
1
Embeds 0
No embeds

No notes for slide
  • Physical development a child&apos;s ability to move, see and hearLanguage and speech development a child&apos;s ability to talk and communicateSocial and emotional development a child&apos;s ability to play, interact and relate to othersAdaptive development a child&apos;s ability to handle self-care functions, such as feeding and dressingCognitive development a child&apos;s ability to think and learn 
 
  • The occupational therapist is trained to modifying the physical environment as well as training the person to use assistive equipment to increase independence. They focus to help their patients engage in meaningful activities of daily living (ADLs). The physical therapist is trained to identifying and maximizing quality of life and movement potential within the spheres of promotion, prevention, diagnosis, treatment/intervention, and rehabilitation. They focus on the physical, psychological, emotional, and social well-being.
  • Transcript of "Holoprosencephaly"

    1. 1. Holoprosencephaly { Living with HoPE
    2. 2. HPE  Birth defect which occurs during the first few weeks of gestation.  Brain does not divide into separate hemispheres  Ranges from mild to severe
    3. 3. HPE  Affects between 1 in 5,000-10,000 live births  Frequency may be as high as 1 in 200-250   < 3% of all fetuses with HPE survive to delivery Majority won’t survive past 6 months ~Carter Centers for Brain Research in Holoprosencephaly and Related Malformations
    4. 4. HPE  Cause Unknown  Chromosomal abnormalities identified in some patients  X-linked recessive in some families
    5. 5. HPE risk factors  Maternal diabetes  Drugs during pregnancy     Aspirin Lithium Anticonvulsants Infections during pregnancy    Syphilis Toxoplasmosis Herpes
    6. 6. HPE Alobar No Division  Semilobar Partial Division  Lobar Divided with areas of fusion  MIV (middle interhemispheric variant) Mid brain not well divided 
    7. 7. HPE symptoms  Excessive fluid in the brain  Varying degrees of mental retardation  Epilepsy  Other organ system abnormalities   cardiac, skeletal, gastrointestinal Degree of delay correlates with severity of malformation
    8. 8. HPE physical characteristics  Primarily Facial Deformities      Small head Single-nostril nose Close set eyes Cleft lip/palate Cyclopia
    9. 9.   Control with medication Telling other students what to expect   Unexpected seizures can be scary for everyone What to do in an emergency Epilepsy
    10. 10.  Tube feeding can be given in 3 different ways     Tube positioning      Pump Gravity drip Syringe Jejunostomy Gastrostomy Nasogastric Keeping area around tube clean Usually the responsibility of the school nurse Gastrointestinal
    11. 11.  Depending on degree of delay students may experience difficulty with        Learning Communication Social & Independent skills Academic Leisure & Work skills Acquisition & Transfer of skills Difficulty with physical/motor Cognitive
    12. 12.      Physical Language and speech Social and emotional Adaptive Cognitive Early Intervention
    13. 13.       Developmental teachers Occupational therapists Physical therapists Speech and language pathologist/audiologists Vision consultants Hearing consultants 
 Early Intervention
    14. 14.  “In its simplest terms, occupational therapists and occupational therapy assistants help people across the lifespan participate in the things they want and need to do through the therapeutic use of everyday activities (occupations). Common occupational therapy interventions include helping children with disabilities to participate fully in school and social situations, helping people recovering from injury to regain skills, and providing supports for older adults experiencing physical and cognitive changes.”  - See more at: http://www.aota.org/AboutOccupational-Therapy.aspx#sthash.rvNWxQB7.dpuf Occupational Therapy
    15. 15.  “Physical therapists can teach patients how to prevent or manage their condition so that they will achieve long-term health benefits. PTs examine each individual and develop a plan, using treatment techniques to promote the ability to move, reduce pain, restore function, and prevent disability. In addition, PTs work with individuals to prevent the loss of mobility before it occurs by developing fitness- and wellness-oriented programs for healthier and more active lifestyles.”  http://www.apta.org/aboutPTs/ Physical Therapy
    16. 16. http://familiesforhope.org  The Carter Centers for Brain Research in Holoprosencephaly & Related Malformations  http://www.carterdatabase.org/hpe/ Information & Assistance
    17. 17. Cognitive http://www.nsnet.org/start/cognitive.pdf Early Intervention http://www.earlyinterventionsupport.com/therapyoptions/early/default.aspx Epilepsy http://www.epilepsyfoundation.org/livingwithepilepsy/parentsandcaregivers /parents/your-child-at-school.cfm Gastrointestinal http://www.health.qld.gov.au/nutrition/resources/etf_tfah.pdf Information and Assistance http://familiesforhope.org Occupational & Physical Therapy http://www.otplan.com/articles/differences-between-occupational-therapyand-physical-therapy.aspx http://www.aota.org/About-Occupational-Therapy.aspx http://www.apta.org/aboutPTs/ References
    1. A particular slide catching your eye?

      Clipping is a handy way to collect important slides you want to go back to later.

    ×