HARNESSING PHARMA  WORKFLOW WITH ELNs
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HARNESSING PHARMA

HARNESSING PHARMA
WORKFLOW WITH ELNs

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  • Merck implemented in 2000 Glaxo – 3500 R&D usersEli Lilly states productivity increase, ROI 5%
  • Rose liked this one
  • Thick/thin client; thick client needs application install Internet Exporer is thin Thick need an application to run; Skype

HARNESSING PHARMA WORKFLOW WITH ELNs Presentation Transcript

  • 1. HARNESSING PHARMA
    WORKFLOW WITH ELNs
    • ELECTRONIC LABORATORY NOTEBOOKS
    WANDA HARTMANN OEHRLI
  • 2. Contents
    20% growth rate per year
    one of the fastestgrowing technologies
  • 3. ELN
    • A daily record-keeping of the pharma process that includes at least the content of a paper notebook
    • 4. Helps to manage data from discovery to commercialization
  • Pharma Workflow Example
  • 5. Importance of Notebooks
  • 6. Necessity of ELNsACCELERATION OF DRUG DISCOVERY!
  • 7. Current ELN Users
    http://www.genengnews.com/articles/chitem.aspx?aid=2481
  • 8. Barriers to Implementation
  • 9. Resistance levels are low
  • 10. ELN Architecture
    Database
    Application/Web server
    Software mainly
    handles work process
    flow
    PDA laptop Computer
    Copies of files will reside locally, short and long term on webservers and DB
  • 11. Most Popular Vendor
  • 12. Predictions
  • 13. Recommendations
    :
  • 14. References
    http://www.informationliberation.com/files/anthraxVaccine.jpg
    http://www.healthsystem.virginia.edu/internet/uvamellon/images/DrugDiscovery.jpg
    http://www.clinical-trials-info.com/wp-content/uploads/2009/02/drug-discovery-11.jpg
    http://www.labtronics.com/Images/eln-small.jpg
    http://en.wikipedia.org/wiki/Electronic_lab_notebook
    http://acdlabs.typepad.com/my_weblog/2007/07/electronic-lab-.html
    http://www.krackeler.com/graphics/0007/jpg/63001000a1.jpg
    http://www.labtrack.com/files/q1_blank_screen.jpg
    http://www.genengnews.com/articles/chitem.aspx?aid=1075
    www.indiana.edu/~cheminfo/C571/ELNlecture20030825.ppt
    http://www.scientific-computing.com/products/product_details.php?product_id=302
    http://knol.google.com/k/shawn-mcclelland/electronic-lab-notebooks/3mhmqlqy4k0no/1#
    http://www.scientificcomputing.com/Electronic-Laboratory-Notebooks-Enter-Mainstream-Informatics.aspx
    Elliott, Michael H; Electronic Laboratory Notebooks: A Foundation for Scientific Knowledge Management Edition III; Atrium Research & Consulting LLC; Wilton, CT USA
    http://www.measurementdevices.com/index.php?name=News&file=article&sid=1597
    http://www.chem.agilent.com/en-US/Products/software/kalabieeln/Pages/default.aspx
    http://www.streetinsider.com/Earnings/Symyx+Announces+Electronic+Laboratory+Notebook+and+LIMS+Partnership+With+Thermo+Fisher+Scientific/4491417.html
    Some images are from Microsoft Clip Art
    http://www.medicalnewstoday.com/articles/29934.php (resistance to ELN)
    http://www.pr.com/press-release/44174 (LabTrak)
    http://www.ddw-online.com/industrynews/124013/new_enterprise_electronic_lab_notebook.html (Symex notebook)
    Networking will slow things down; cost http://pipeline.corante.com/archives/2008/02/07/write_it_down_write_it_down.php
    http://www.genengnews.com/articles/chitem.aspx?aid=2481
    http://www.phschool.com/science/science_news/articles/images/electron_runs_through_01.jpg
    http://www.sxst.it/siti/sxst/sxst.nsf/seminari/cambridgesoft/ELN-Intro.pdf
    Pharma company logs came from company websites.
    Google Keyword searches
    • review of ELN electronic laboratory notebook
    • 15. Market potential for electronic laboratory notebook at pharmaceutical companies
    • 16. cost of electronic laboratory notebooks
    • 17. cost of cambridgesofteln
    • 18. I would like to acknowledge help from IT experts, friends and family who reviewed this presentation.