Early Detection of Recurrent Breast Cancer Using Metabolite Profiling Reflection Even with all the advances of science to date, breast cancer is still the leading cause of death forwomen worldwide. Most methods and techniques used to detect breast cancer are imprecise andunreliable. For this reason, research is being done to find newer, more reliable methods to detect cancerat an early stage. Scientists are trying to identify cancer using blood based tumor markers. In her paper,Leidy Alvarado, presents research she is currently doing on markers for recurrent cancer. For this study,serum was acquired from several patients that were previously diagnosed with breast cancer, twenty ofthem having had recurrent breast cancer. In order to detect possible markers, several profiling methodswere used on the samples, such as nuclear magnetic resonance (NMR) and two-dimensional gaschromatography-mass spectrometry (GCxGC-MS). With these techniques, they were able to identify anumber of eleven potential biomarkers for breast cancer, and were able to develop a model to detectthe possibility of recurrence in cancer patients. These findings are revolutionary for the oncological field, for it allows a more accurate and moreeffective method to detect cancer in patients. This will also allow surviving cancer patients to determineif they are truly free of cancer and be able to detect a recurrence in early stage. These results representa closer step for cancer diagnosis and treatment.