Seminar 1: Stem Cells Wilmarie Morales During this seminar we were able to learn about recent studies being done with gliomatumors and stem cell biology. Jessian, our presenter for the day, made the presentation easierto follow by using images and tables along with his explanations. A few things we learned in thepresentation were that stem cells are biological cells found in all multicellular organisms, thatcan divide into, either, diverse specialized cell types or more stem cells. Stem cells can be foundin almost any vital organ in the body, like: the liver, lungs and colon. Stem cells can also befound in the brain, and are called glia. Gliomas are a type of tumor that start in the brain orspine. Gliomas have a very strong resemblance to glia cells. Glioblastoma multiform is the mostcommon and most dangerous of these tumors. In the seminar we were informed that these tumors are chemo resistant and thereforemortal. Currently researchers are trying to find a way to make these tumors susceptible tochemotherapy. They are trying to do this through the sonic hedgehog pathway and miRNA.Results of several experiments have confirmed that by adding miRNA to these cells they canbecome vulnerable to chemotherapy. These results have a profound significance for science. With these findings it may bepossible to find a way to treat and even cure the occurrence of glioma tumors. Not only dothese findings have an impact for further studies done on glioma tumors, but also for futureresearch that is being done in the fields of oncology (in finding new innovative treatments for
several other cancers) and neurology (using the knowledge of regenerating brain cells to treatmany neurological diseases).