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Poster List

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    • Poster List2010Elferink, M.G.L., Olinga P., van Leeuwen E.M., Bauerschmidt S., Polman J., Schoonen W.G., Heisterkamp S.H., Groothuis G.M.M. (2010a). Gene expression analysis of precision cut human liver slices indicate stable expression of ADME-Tox related genes. Eurotox, BarcelonaElferink, M.G.L., Olinga P., van Leeuwen E.M., Bauerschmidt S., Polman J., Schoonen W.G., Heisterkamp S.H., Groothuis G.M.M. (2010b). Gene expression analysis of precision cut human liver slices indicate stable expression of ADME-Tox related genes. Gordon conference.Vermeulen, N., Augustijn, A., Russel, F., Groothuis, G., Pieters, R., Water, van de B. Commandeur, J., Irth, H., Burg, van der B., Janssen, R., Joore, J., Brilleman, A., Emmen, H., Schoonen, W., and Koster, H. (2010). Translational biomarkers for adverse drug reactions. TI Pharma Meeting, April, Utrecht.2009Bovee, T.F.H., Thevis, M., Schoonen, W.G.E.J., Weigel, S., and Nielen, M.W.F. (2009). Bioassay screening of SERMs and SARMs in pharmacology, food supplements and sports doping. 4th International Symposium on Recent Advances in Food Analysis (RAFA 2009), 4 th to 6th November, Prague, Czech Republic.Gracanin, A., Sartorius, C.A., Koepfli, K.P., Wayne, R.K., Schoonen, W.G., and Mol, J.A. (2009). The fairy tail of canine progesterone receptor. Gordon Conference, Hormone action in development and cancer. 26 th to 31th July, Holderness, United States.Lauwers, A., Griffioen,G., Wera, S., Duhamel, H., Vandamme, N., Schoonen, W., and Westerink, W., (2009) A yeast-based screening method for genotoxic and clastogenic compounds compatible with S9 metabolic activation. 15th International Congress on In Vitro Toxicology, IVTIP 2009, 26 th October, Edegem (near Antwerp), Belgium.Schoonen, W.G.E.J., Westerink, W.M.A., Stevenson, J.C.R., and Horbach, G.J. (2009). RAD51C, Cystatin A, p53, and Nrf2 luciferase-based reporter assays in metabolic competent HepG2 cells for the rapid assessment of genotoxicity and oxidative stress in the early research phase. 46 th Congress of the European Societies of Toxicology, EUROTOX2009, 13 th to 16th September, Dresden, Germany.Westerink, W.M.A., Stevenson, J.C.R., Horbach, G.J. and Schoonen, W.G.E.J., (2009) . The development of RAD51C, Cystatin A, P53 and Nrf2 luciferase reporter assays in metabolic competent HepG2 cells for the assessment of mechanistic genotoxicity and of oxidative stress in the early research phase. 18th Netherlands Society of Toxicology (NVT) Anniversary Meeting, NVT2009, 18 th and 19th June, Veldhoven, The Netherlands.Westerink, W.M.A., Stevenson, J.C.R., Horbach, G.J. and Schoonen, W.G.E.J., (2009) . The development of RAD51C, Cystatin A, P53 and Nrf2 luciferase reporter assays in metabolic competent HepG2 cells for the assessment of mechanistic genotoxicity and of oxidative stress in the early research phase. INVITROM Meeting, 2009, 25th November, Edegem near Antwerp, Belgium.2008Lauwers, A., Griffioen,G., Wera, S., Duhamel, H., Vandamme, N., Schoonen, W., and Westerink, W., (2008) A yeast-based screening method for genotoxic and clastogenic compounds compatible with S9 metabolic activation. 15th International Congress on In Vitro Toxicology, ESTIV2008, 25 th to 28th September, Stockholm, Sweden.2007Elferink, M.G.L., Olinga, P., Draaisma, A.L., Merema, M.T., Zeinstra, M., Bauerschmidt, S., Polman, J, Schoonen, W.G. and Groothuis, G.G.M. (2007). Early markers of toxicity. Microarray analysis of hepatotoxicity in vivo and in vitro. Pharmaceutical Sciences World Congress.Elferink, M.G.L., Olinga, P., Draaisma, A.L., Merema, M.T., Bauerschmidt, S., Polman, J, Schoonen, W.G. and Groothuis, G.G.M. (2007). Early markers of toxicity. Microarray analysis of hepatotoxicity in vivo and in vitro. Eurotox, 7-10 October, 2007. Toxicology Letters 172, Suppl.1, S77.Westerink, W.M.A., Stevenson, J.C.R. and Schoonen W.G.E.J. (2007) CYP1A induction and species differences between human HepG2 and rat H4IIE cells. SSCT Salzau, Germany, 19-22 September, 2007.Westerink, W.M.A., Stevenson, J.C.R. and Schoonen W.G.E.J. (2007) CYP1A induction and species differences between human HepG2 and rat H4IIE cells. Amsterdam, The Netherlands, Eurotox, 7-10 October, 2007. Toxicology Letters 172, Suppl. 1, S98.Olinga, P., Elferink, M.G.L., Bauerschmidt, S., Polman, J., Schoonen, W.G.E.J., Draaisma, A.L., Merama, M.T., and Groothuis, G.M.M. (2007). Gene network analysis of acetaminophen and carbon tetrachloride treated
    • rat liver slices identifies hepatotoxicity mechanisms observed in vitro. Figon meeting, Lunteren 1-3 October 2007.Olinga, P., Elferink, M.G.L., Bauerschmidt, S., Polman, J., Schoonen, W.G.E.J., Draaisma, A.L., Merama, M.T., and Groothuis, G.M.M. (2007). Gene network analysis of acetaminophen and carbon tetrachloride treated rat liver slices identifies hepatotoxicity mechanisms observed in vitro. ISXX meeting 2007.2006Schoonen, W.G.E.J., Dijcks, F.A., de Gooyer, M.E., Peters, J.L.M. and Ederveen, A.G.H. (2006). Pharmacology of selective agonists and antagonists for estrogen receptor α and : in vitro activities in CHO and MCF-7 cells and in vivo activity in rats on female lordosis behavior. J.Steroid Biochem. Mol. Biol. Seefeld, Austria, 1-3 June 2006.Westerink, W.M.A. and Schoonen, W.G.E.J. (2006a). Phase I enzyme levels in cryopreserved primary human hepatocytes and HepG2 cells and their induction in HepG2 cells. Invitox, Oostende, 2-5 October 2006.Westerink, W.M.A. and Schoonen, W.G.E.J. (2006b). Phase II enzyme levels in cryopreserved primary human hepatocytes and HepG2 cells and their induction in HepG2 cells. Invitox, Oostende, 2-5 October 2006.2005Westerink, W. and Schoonen, W.G.E.J. (2005). Characterisation of phase I and II enzymes. Technician day, Solvay-Duphar, Weesp, 24 may, 2005.Westerink, W. and Schoonen, W.G.E.J. (2005). Characterisation of phase I and II enzymes. NVT meeting, Organon, Oss, 7-8 June 2005.Schoonen, W.G.E.J., Westerink, W.A.J., Horbach, G.J.M.J., Ploemen, J._P.H.T.M., Polman, J.E.M., and Proustki, V. (2005). Toxicogenomics on rat and human liver. NVT meeting, Organon, Oss, 7-8 June 2005.Schoonen W.G.E.J., Smit M.J., Zandberg P., Horbach G.J.M.J., Ploemen J._P.H.T.M., Kloks C.P.A.M., Mellema J.R., Thijssen-van Zuylen C., Vogels J.T.W.E., Tas C.A. and van Nesselrooij J.H.J. (2005). Uniform procedure of 1H NMR analysis of rat urine with respect to toxico-metabonomics. NVT meeting, Organon, Oss, 7-8 June 2005.Lierop van, M.J.C., Vleuten, van M., Smets, R., Klop, H., Boerakker, R., Evers S., Schoonen, W., Dijkema, R., Dokter, W. (2005). The in vitro transrepression / transactivation profile of RU486 does not lead to a dissociating glucocorticoid in vivo in mice. Keystone congres "Tissue-selective NR" (Sept 2005), Breckenridge, Colorado, USA.Schoonen, W.G.E.J., Smit, M.J., Zandberg, P., Horbach, G.J.M.J., Ploemen, J._P.H.T.M., Kloks, C.P.A.M., Mellema, J.R., Thijssen-van Zuylen, C., Vogels, J.T.W.E., Tas, C.A. and van Nesselrooij, J.H.J. (2005). Uniform procedure of 1H NMR analysis of rat urine with respect to toxico-metabonomics. Eurotox 2005, Krakau, September. Toxicology Letters 158, Suppl. 1, September 2005, P15-18.Westerink, W.M.A. and Schoonen, W.G.E.J. (2005). Characterisation of phase I and II enzymes in HepG2 cells. Figon Symposium, Lunteren, 4-5 Oct. 2005.Schoonen W.G.E.J., Smit M.J., Zandberg P., Horbach G.J.M.J., Ploemen J._P.H.T.M., Kloks C.P.A.M., Mellema J.R., Thijssen-van Zuylen C., Vogels J.T.W.E., Tas C.A. and van Nesselrooij J.H.J. (2005). Uniform procedure of 1H NMR analysis of rat urine with respect to toxico-metabonomics. Figon Symposium, Lunteren, 4-5 Oct. 2005.2003Schoonen, W.G.E.J., Westerink, W.M.A., de Roos, J.A.D.M. and Débiton, E. (2003). Cytotoxic effects of 100 reference compounds on Hep G2 and HeLa cells. Florence (poster), Eurotox 2003.2001Schoonen, W.G.E.J., Westerink, W.M.A., de Roos, J.A.D.M. and Débiton, E. (2001). The effects of several toxic reference compounds on Hep G2, HeLa, ECC-1 and CHO cells with Dichlorofluorescein diacetate, monochlorobimane and Calcein-AM mechanistic assays. Washington (poster), In vitro toxicology.Schoonen, W.G.E.J., Westerink, W.M.A., de Roos, J.A.D.M. and Débiton, E. (2001). Cytotoxic effects of several toxic reference compounds on Hep G2, HeLa, ECC-1 and CHO cells with ATP-Lite, Cyto-Lite, Alamar Blue and Hoechst 33342 assays. Washington (poster), In vitro toxicology.2000Schoonen, W.G.E.J., Deckers, G., Gooijer, de M.E., Ries de, R., Mathijssen-Mommers, G., Hamersma, H., and Kloosterboer, H.J. (2000): Contraceptive progestins: Various 11-substituents combined with four 17- substituents: 17-ethynyl, five- and six-membered spiromethylene ethers or six-membered spiromethylene lactones. 14th International Symposium of the Journal of steroid Biochemistry & Molecular Biology (poster), Quebec City, June 24-27, 2000. Abstract 40P.
    • 1999Schoonen, W.G.E.J., Ries de, R.J.H., Joosten, J.W.H., Mathijssen-Mommers, G. and Kloosterboer, H.J. (1999): Development of high throughput in vitro bioassays for steroid receptors. SBS conference Edinburgh (poster), Sept 13-16, Scotland. Abstract.1998Schoonen, W.G.E.J., Mosselman, S. and Kar, S.A.T (1998): Comparison of human estrogen receptor  and ß in binding and transactivation assays. Xth International congress on hormonal steroids. Quebec City (poster), June 17-21, Canada. Abstract 3, Page 108.1997Schoonen, W.G.E.J., Ries de, R.J.H., de Gooyer, M.E., Deckers, G.H. and Kloosterboer, H.J. (1997). Hormonal properties of norethisterone and its derivatives and the effect of a 7-methyl substitution. Symp.of J. Steroid Biochem. and Molec. Biol. (poster), May, Monaco.1996Vermeulen G.J., Schoonen W.G.E.J., Kloosterboer H.J. (1996): The effect of antiprogestagens on the interactions between progesterone receptor and DNA. Sex Hormones and Cancer (in association with the Journal of Steroid Biochemistry and Molecular Biology), San Francisco USA (poster), 9-11 June 1996.1995Dijkema R., Teuwen R., Struik van der E., Wagenaars J.L., Ries de R.J.H., Joosten J.W.H. and Schoonen W.G.E.J. (1995): Human progesterone receptor isoforms B and A: characterization of their individual ligand binding properties in relation to transcriptional activation. Symposium of Steroid Biochemistry and Molecular Biology (poster), May 1995, Berlin.Hakola K., Haavistol A.M., Boogaart P. v.d., Mulders J., Schoonen W., Heyst J. v., Swolfs A., Casteren J. v., Huhtaniemi I., Kloosterboer H. (1995): Characterization of recombinant rat LH. Abstract (poster), annual meeting of Finnish Endocrine Society.Mosselman S., Teuwen R., Schoonen W. and Dijkema R. (1995): The use of CHO cells stably transfected with the human androgen or progesterone receptor together with a reporter in profiling (anti)androgens and (anti-)progestagens. Abstract to be used at: Congress Mechanism of Action of retinoids, vitamin D and steroid hormones. Whistler, Canada, January 1995.Schoonen, W.G.E.J., de Ries, R.H.J., Mommers, G.J.W., de Gooyer, M.E., Struik E., Dijkema R. (1995): The human glucocorticoid receptor: comparison of binding and transcription modulation with CHO hGR- MMTV-LUC cells versus binding with IM-9 cells.Keystone Symposium 96 Steroid receptors (poster), California, USA.1994Dijkema R., Teuwen R. , Swinkels J.C. and Schoonen W.G.E.J. (1994): The human progesterone B receptor: Inhibition of transcription activation by antagonists in CHO cells stably transfected with receptor and reporter. [Keystone Symp, Steroid/thyroid/retinoic acid super gene family, Taos, New Mexico, February 7- 13, 1994]. J. Cell. Biochem. Suppl 18B, 342, Abstract K 111 (poster).Orlemans E.O.M., Deckers, G.H., Schoonen, W.G.E.J., Kloosterboer H.J. (1994): Pharmacology of the very selective antiprogestin Org 31710 and comparison with the antiprogestins RU38486 and ZK98299. Poster IX International Congress on Hormonal Steroids, Sept. 24-29, Dallas, USA (poster).Schoonen, W.G.E.J., Joosten, J.W.H. and Kloosterboer, H.J. (1994): Effects of progestagens on cell growth of human breast tumor cells. Keystone Symposium, Steroid/thyroid/ retinoic acid super gene family, Taos, New Mexico, February 7-13, 1994. J. Cell. Biochem. Suppl. 18B, 372, Abstract K 347 (poster).1993Schoonen W.G.E.J., Joosten J.W.H. and Kloosterboer H.J. (1993): Effects of progestagens on cell growth of human breast tumor cells. Poster presentatie 11th International Symposium of Steroid Boichemistry and Molecular Biology, Seefeld, Austria, May 30 - June 2, 1993.1992Slootweg M.C., Ederveen A.G.H., Schot L.P.C., Schoonen W.G.E.J. and Kloosterboer H.J. (1992): Estrogen and progestagen synergistically stimulate osteoblast proliferation. (Abstract, XI th ICCRH, Florence).Kloosterboer H.J., Schoonen W.G.E.J. and Deckers G.H. (1992): Effects of synthetic steroids in in vitro and in vivo tumor models. Meeting of Internat. Study Group of Steroid Hormones, Vienna, Austria.
    • 1989Schoonen, W.G.E.J., Wanamarta, A.H., and Joenje, H. (1989). Inactivation of specific mitochondrial enzymes by hyperoxia in Chinese hamster ovary cells. Symposium on: Free radicals and cancer, 8-9 December 1989 (poster), Tübingen, Germany.Wanamarta, A.H., Schoonen, W.G.E.J., and Joenje, H. (1989). Inactivation of specific mitochondrial enzymes by hyperoxia in HeLa cells. Symposium on: Free radicals and cancer, 8-9 December 1989 (poster), Tübingen, Germany.1988Schoonen, W.G.E.J., Wanamarta, A.H., and Joenje, H. (1988). Effect of hyperoxia on respiratory activity of CHO cells. Symposium on: Free radicals and cancer, November 1988 (poster), Vienna, Austria.1986Schoonen, W.G.E.J., Penders, M.T., van Dam, G.H. and Lambert, J.G.D. (1986). 5ß-Pregnane-3,6,17,20ß- tetrol and 5ß-pregnane-3,6,17-triol-20-one: steroids of ovarian origin in the African catfish, Clarias gariepinus, during oocyte maturation. Symposium of Comparative Endocrinology (poster). Belgrad, Yugoslavia.1985Schoonen, W.G.E.J. and Lambert, J.G.D. (1985). Steroidogenesis in the testes and seminal vesicles of Clarias gariepinus in spawning and non-spawning animals under natural conditions and in non-spawning animals kept in ponds. Symposium on Fish Culture by the European Society for Comparative Physiology and Biochemistry (poster). 26-28 August, Barcelona, Spain.1981Schoonen, W.G.E.J., Oudejans, R.C.H.M., and Voogt, P.A. (1981). Production of NADPH and acetyl CoA for lipid biosynthesis in the pyloric caeca of the sea star, Asterias rubens. (poster) Newcastle upon Tyne, United Kingdom.