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Amp keynote wilbanks

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Opening talk at the reproducible research workshop at AMP 2011, Vancouver.

Opening talk at the reproducible research workshop at AMP 2011, Vancouver.

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  • 1. freedom (to reproduce) john wilbanks @creativecommons @wilbanks 14 July 2011
  • 2. freedom .
  • 3. 1. reproducibility > sharing. 2. best practices.3. freedom (as in “to reproduce”).
  • 4. non-reproducible = people die.
  • 5. CITATIONS 500 1000 1500 2000 2500 3000 0 ERa AR PPARa PPARg PR GR RARa VDR MR PXR LXRa available LXRb PPARd FXR Chemical probe TRb CAR RORg NGFIBa ERb NGFIBb HNF4a RORa SHP ERRa SF1 DAX Rev-erba RARb COUP2 RARg TRa ERRg LRH1 COUP1 availableNUCLEAR HORMONE RECEPTOR NGFIBg Rev-erbb RXRa RXRb No chemical probes RXRg the easier it is to reproduce chemically… PNR ERRb (slide courtesy of RORb GCNF Aled Edwards, SGC) TLX TR2 TR4 COUP3 HNF4g
  • 6. reproducibility as collaboration.
  • 7. http://www.flickr.com/photos/creativecommons/
  • 8. note: not a scientist.
  • 9. 1. reproducibility > sharing. 2. best practices.3. freedom (as in “to reproduce”).
  • 10. old school
  • 11. new school
  • 12. 1. reproducibility > sharing. 2. best practices.3. freedom (as in “to reproduce”).
  • 13. reality.
  • 14. “open” and “closed” aren’t even on the menu here.
  • 15. re-identification
  • 16. consenting to uncertainty.
  • 17. Browser WindowFreedoms you are granting✓ Right to do research with your data✓ Right to redistribute your data✓ Right to publish results of research from your data✓ Right to commercialize products derived from research on your data
  • 18. Browser WindowObligations you are imposing✓ I don’t want to be re-identified✓ Only health research allowed.
  • 19. Browser WindowCheck to confirm that:✓ I understand the risks✓ I consent that my data can be used for research. Although I can withdraw at any time,✓ versions of my data that are already distributed may not be retrievable. Warning You must click yes on each element to proceed.
  • 20. freedom .
  • 21. freedom isn’t always about politics.

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